336 studies found for:    HSV
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Rank Status Study
1 Recruiting Study of the Safety of a Particular Herpes Vaccine in Adults With or Without Herpes Infection
Conditions: Genital Herpes;   Herpes Simplex Virus;   Herpes Simplex Virus Vaccines;   HSV Vaccines;   Herpesvirus Vaccines
Intervention: Biological: HSV529
2 Completed Humoral and Cellular Immune Response of Herpes Simplex (gD) Candidate Vaccines From 2 Different Cell Lines
Condition: Prophylaxis Herpes Simplex
Interventions: Biological: Adjuvanted herpes simplex (gD) candidate vaccine GSK 208141;   Biological: Herpes simplex virus containing gD-Alum
3 Completed Evaluation of Immunogenicity, Reactogenicity and Safety of Herpes Simplex (gD) Candidate Vaccine With/Without Adjuvant
Condition: Prophylaxis Herpes Simplex
Interventions: Biological: Herpes simplex candidate vaccine GSK208141 - non-MPL-containing adjuvant;   Biological: Herpes simplex candidate vaccine GSK208141- MPL-containing adjuvant
4 Completed HSV-2 Suppression to Reduce HIV-1 Levels in HIV-1, HSV-2 Co-infected Men.
Conditions: HIV Infection;   Herpes Simplex;   Sexually Transmitted Diseases
Interventions: Drug: valacyclovir;   Drug: matching placebo
5 Completed Safety Evaluation of Herpes Simplex Candidate Vaccine (gD2t) With Adjuvant in HSV Seropositive / Seronegative Subjects
Condition: Prophylaxis for Herpes Simplex
Interventions: Biological: Herpes simplex candidate vaccine- adjuvanted GSK 208141;   Biological: Placebo
6 Recruiting Identification of Herpes Simplex Virus (HSV) Shedding in the Female Genital Tract of Pregnant and Nonpregnant Women by GeneXpert PCR, Routine PCR, and Culture
Condition: Herpes Simplex Virus
Intervention: Device: Genexpert assay
7 Completed Safety of a Herpes Simplex Candidate Vaccine (gD2t) With MPL and Its Efficacy to Prevent Genital Herpes Disease
Condition: Prophylaxis Herpes Simplex
Interventions: Biological: Herpes simplex candidate vaccine- adjuvanted GSK208141;   Biological: Placebo injection
8 Completed
Has Results
Trial to Study the Effect of Dose of Herpes Simplex Virus-2 (HSV-2) Suppressive Therapy on HSV and HIV
Conditions: Genital Herpes;   HIV Infection
Interventions: Drug: valacyclovir;   Drug: acyclovir
9 Terminated A Study of HSV Testing Among Pregnant Women
Conditions: Herpes Simplex;   Pregnancy
Interventions: Behavioral: Safer-sex counseling;   Procedure: Type specific serologic HSV testing
10 Active, not recruiting Seroprevalence of HSV-2 in HIV Infected Subjects and the Effect of Daily Valacyclovir in the Reduction of HSV-2 Recurrence and Viral Shedding
Conditions: HSV-2;   HIV;   HIV Infections
Interventions: Drug: Valacyclovir;   Drug: Placebo
11 Recruiting Intrapleural Administration of HSV1716 to Treat Patients With Malignant Pleural Mesothelioma.
Condition: Malignant Pleural Mesothelioma
Intervention: Biological: HSV1716 Intra-pleural delivery
12 Recruiting HSV1716 in Patients With Non-Central Nervous System (Non-CNS) Solid Tumors
Condition: Non-CNS Solid Tumors
Intervention: Biological: HSV1716
13 Completed Safety Study of HSV2 DNA Vaccine to Treat Patients With Recurrent Genital Herpes Caused by HSV-2
Condition: HSV-2
Intervention: Biological: pPJV7630 administered by PMED
14 Completed Usage of Acyclovir for Suppression of HIV-1 and HSV-2 Coinfected Persons in Cameroon
Conditions: HIV-1 and HSV-2 Coinfection;   HIV Infections
Intervention: Drug: Acyclovir
15 Recruiting Dose Ranging Safety and Efficacy of Therapeutic HSV-2 Vaccine
Condition: Genital Herpes Simplex Type 2
Interventions: Biological: Matrix-M2 Adjuvant;   Biological: GEN-003 Vaccine;   Drug: Placebo
16 Recruiting Oncolytic HSV-1716 in Treating Younger Patients With Refractory or Recurrent High Grade Glioma That Can Be Removed By Surgery
Conditions: Recurrent Childhood Anaplastic Astrocytoma;   Recurrent Childhood Anaplastic Oligoastrocytoma;   Recurrent Childhood Anaplastic Oligodendroglioma;   Recurrent Childhood Giant Cell Glioblastoma;   Recurrent Childhood Glioblastoma;   Recurrent Childhood Gliomatosis Cerebri;   Recurrent Childhood Gliosarcoma
Interventions: Biological: oncolytic HSV-1716;   Drug: dexamethasone;   Procedure: therapeutic conventional surgery;   Other: laboratory biomarker analysis
17 Completed
Has Results
HerpeVac Trial for Young Women
Condition: Herpes Simplex Infection
Interventions: Biological: HSV vaccine or SB208141, GSK Biologicals' glycoprotein D (gD)-Alum/3-deacylated form of Monophosphoryl Lipid A (MPL) candidate genital herpes vaccine;   Biological: Havrix™, GlaxoSmithKline (GSK) Biologicals' licensed Hepatitis A vaccine
18 Recruiting Herpes Simplex Type 1 Suppression in Hepatitis C
Condition: Chronic Hepatitis C Infection
Interventions: Drug: Valacyclovir;   Drug: Placebo
19 Not yet recruiting A Multiple Ascending Dose-Finding Pharmacokinetic and Pharmacodynamic Study of a Novel Antiviral Drug in Infants With Neonatal Herpes Simplex Virus (HSV)
Condition: Herpes Simplex Virus
Interventions: Drug: Novel Antiviral Drug;   Drug: Placebo
20 Completed Study to Compare Safety and Immunogenicity of Commercial Scale Consistency Lots of Herpes Simplex Vaccine
Condition: Herpes Simplex
Intervention: Biological: GSK208141 vaccine

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Indicates status has not been verified in more than two years