11 studies found for:    GlyT-1
Show Display Options
Rank Status Study
1 Completed GlyT-1 Inhibitor Treatment for Refractory Schizophrenia
Conditions: Schizophrenia;   Treatment Refractory
Interventions: Drug: GlyT-1 inhibitor-1;   Drug: Placebo
2 Completed Research Involving Subjects With Parkinson's Disease, Alzheimer Disease and Healthy Controls
Conditions: Parkinson Disease;   Alzheimer Disease
Intervention: Drug: [18F] CFPyPB
3 Recruiting Translational Neuroscience Optimization of GlyT1 Inhibitor
Condition: Cognitive Impairments Associated With Schizophrenia
Interventions: Drug: PF-03463275;   Drug: Placebo
4 Terminated A Repeat Dose Study With GSK1018921 to Assess Safety, Tolerability, Pharmacokinetics, Pharmacodynamics in Healthy Volunteers and Patients With Schizophrenia and to Evaluate Its Effect on PK of Midazolam.
Condition: Schizophrenia
Intervention: Drug: Glycine Transporter-1 inhibitor
5 Unknown  Effect of Sarcosine on Symptomatology, Quality of Life, Oxidative Stress and Glutamatergic Parameters in Schizophrenia
Condition: Schizophrenia
Intervention: Dietary Supplement: Sarcosine
6 Completed Sarcosine or D-Serine Add-on Treatment for Chronic Schizophrenia
Conditions: Schizophrenias;   Psychoses;   Psychotic Disorders;   Schizophrenic Disorders
Intervention: Drug: Sarcosine and D-serine
7 Completed First Time in Human Study With GSK1018921
Condition: Schizophrenia
Interventions: Drug: active Comparator Nicotine;   Drug: GSK1018921
8 Completed D-amino Acid Oxidase Inhibition (DAAOI-1) add-on Treatment for Chronic Schizophrenia
Conditions: Schizophrenias;   Psychoses;   Psychotic Disorders;   Schizophrenic Disorders
Interventions: Drug: D-amino acid oxidase inhibition (DAAOI-1);   Drug: placebo
9 Completed A Study of the Effects of Sarcosine on Symptoms and Brain Glycine Levels in People With Schizophrenia
Condition: Schizophrenia
Intervention: Dietary Supplement: Sarcosine
10 Completed
Has Results
The Impact of Pharmacological and Electric Modulation of NMDA Pathway on the Cognitive Flexibility and Volitional Movement Preparation in Patients With Parkinson's Disease
Condition: Parkinson's Disease With Dementia
Interventions: Dietary Supplement: Sarcosine Capsule;   Dietary Supplement: Placebo Capsule
11 Recruiting Phase I Study to Investigate Safety, Tolerability, and Pharmacokinetics of VVZ-149 Injection
Condition: Healthy
Interventions: Drug: VVZ-149 Injection;   Drug: placebo (water for injection)

Indicates status has not been verified in more than two years