166 studies found for:    GLP-1R
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Rank Status Study
1 Recruiting DIabetes REsearCh on Patient sTratification (DIRECT): GLP-1R Agonists
Condition: Diabetes
Intervention: Drug: Exenatide, Liraglutide
2 Completed
Has Results
GLP1R Polymorphisms and Response to GLP1
Condition: Diabetes
Intervention: Drug: GLP-1
3 Terminated TANTALUS Therapy in Type 2 Diabetic Patients Intolerant or Inadequately Responsive to GLP-1 Receptor Agonist Therapy
Condition: Diabetes Mellitus, Type 2
Intervention: Device: TANTALUS System
4 Recruiting Effect of GLP-1 Receptor (GLP-1R) Agonists on Cardiac Function and on Epicardial Adipose Tissue (EAT) Volume and on Myocardial TG Content in Obese Diabetics
Conditions: Obesity;   Diabetes
Interventions: Drug: BYETTA treatment;   Drug: Metformine
5 Completed Glucagon-like Peptide (GLP) Utilization and Safety
Condition: Diabetes Mellitus, Type 2
Interventions: Other: The GLP-1 receptor agonist users;   Other: DPP-4 inhibitor users;   Other: Other ADA users
6 Not yet recruiting Effects of GLP-1 Receptor Agonist on Fat Redistribution and Inflammatory Status
Condition: Obesity
Intervention: Drug: Exenatide
7 Recruiting Changes in Bone Turnover With Exposure to a GLP-1 Receptor Agonist
Condition: Type 2 Diabetes Mellitus
Interventions: Drug: exenatide;   Drug: placebo
8 Recruiting SAFEGUARD: Pleiotropic Effects of Incretin Based Therapies
Condition: Type 2 Diabetes
Interventions: Drug: Liraglutide;   Drug: Sitagliptin;   Drug: Exenatide;   Drug: Liraglutide placebo;   Drug: Sitagliptin placebo;   Drug: Exenatide placebo;   Drug: L-NMMA
9 Active, not recruiting The Effects of Physical Training and GLP-1 Receptor Agonist Liraglutide Treatment in Patients With Type 2 Diabetes
Condition: Type 2 Diabetes
Interventions: Other: Training and liraglutide;   Other: Training and placebo
10 Completed The Efficacy of Insulin Degludec/Liraglutide in Controlling Glycaemia in Adults With Type 2 Diabetes Inadequately Controlled on GLP-1 Receptor Agonist and OAD Therapy
Conditions: Diabetes;   Diabetes Mellitus, Type 2
Interventions: Drug: insulin degludec/liraglutide;   Drug: liraglutide;   Drug: exenatide
11 Recruiting PROMASTER - PROspective Cohort MRC ABPI STratification and Extreme Response Mechanism in Diabetes
Condition: Diabetes
Intervention: Drug: second- or third-line glucose-lowering diabetes treatment
12 Recruiting Does a GLP-1 Receptor Agonist Change Glucose Tolerance in Antipsychotic-treated Patients?
Condition: Impaired Glucose Tolerance Associated With Drugs
Interventions: Drug: Liraglutide;   Drug: Liraglutide Placebo
13 Completed The Effect of GLP-1 Receptor Activation on Central Reward and Satiety in Obesity and Diabetes
Conditions: Diabetes Mellitus;   Diabetes Mellitus, Type 2;   Obesity
Interventions: Drug: exenatide;   Drug: exenatide + exendin (9-39);   Drug: placebo
14 Recruiting A Comparative Effectiveness Study of Major Glycemia-lowering Medications for Treatment of Type 2 Diabetes
Conditions: Type 2 Diabetes;   Comparative Effectiveness of Glycemia-lowering Medications
Interventions: Drug: Sulfonylurea (glimepiride);   Drug: DPP-4 inhibitor (sitagliptin);   Drug: GLP-1 receptor agonist (liraglutide);   Drug: Insulin (glargine)
15 Completed
Has Results
Evaluation of the Glucoregulatory Effects of Glucagon-like Peptide-1 Receptor (GLP-1 Receptor) Activation in Participants With Type 2 Diabetes Mellitus (MK-0000-222)
Condition: Type 2 Diabetes Mellitus
Interventions: Drug: Oxyntomodulin;   Drug: Liraglutide 0.6 mg;   Drug: Liraglutide 1.2 mg;   Drug: Placebo for Oxyntomodulin;   Drug: Placebo for Liraglutide
16 Unknown  GLP-1 Receptors in Normal Skin and Skin From Patients With Psoriasis
Condition: Reduction of Psoriasis Following Liraglutide Therapy in Terms of PASI and DLQI
Interventions: Drug: Liraglutide;   Drug: Placebo
17 Unknown  Whole Body 111In-exendin-4 Imaging Study in Insulinoma Patients
Conditions: Hyperinsulinism;   Hypoglycemia;   Insulinoma
Intervention: Other: 111In-exendin-4 imaging
18 Active, not recruiting Role of Glucagon-Like Peptide-1 in Postprandial Hypoglycemia
Condition: Postprandial Hypoglycemia
Interventions: Drug: exendin-(9-39);   Other: placebo normal saline
19 Completed Exendin(9-39)Amide as a Glucagon-like Peptide-1 (GLP-1) Receptor Antagonist in Humans
Condition: Hyperglycemia
Interventions: Drug: GLP-1 control;   Drug: GLP-1 and Exendin(9-39) 300;   Drug: saline control;   Drug: GLP-1 and Exendin(9-39) 600;   Drug: GLP-1 and Exendin(9-39) 900;   Drug: GLP-1 and Exendin(9-39) 1200
20 Recruiting Effect on Beta Cell Function and Glycaemic Control After Insulin and Exenatide Sequential Therapy
Condition: Type 2 Diabetes
Interventions: Drug: Exenatide;   Drug: Metformin

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Indicates status has not been verified in more than two years