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121 studies found for:    Brain and Spinal Tumors

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Rank Status Study
21 Recruiting Vorinostat, Temozolomide, or Bevacizumab in Combination With Radiation Therapy Followed by Bevacizumab and Temozolomide in Young Patients With Newly Diagnosed High-Grade Glioma
Conditions: Childhood High-grade Cerebellar Astrocytoma;   Childhood High-grade Cerebral Astrocytoma;   Childhood Spinal Cord Neoplasm;   Untreated Childhood Brain Stem Glioma;   Untreated Childhood Cerebral Astrocytoma
Interventions: Drug: vorinostat;   Biological: bevacizumab;   Drug: temozolomide
22 Terminated Intrathecal Gemcitabine to Treat Neoplastic Meningitis, IT Gemcitabine
Conditions: Meningitis;   Neoplasms
Intervention: Drug: Gemcitabine
23 Recruiting Radiation Therapy or Combination Chemotherapy in Treating Patients With Clinically or Radiologically Progressive Low-Grade Gliomas
Condition: Brain and Central Nervous System Tumors
Interventions: Drug: vincristine, carboplatin;   Drug: vincristine, carboplatin, etoposide;   Radiation: radiation therapy
24 Active, not recruiting Erlotinib and Radiation Therapy in Treating Young Patients With Newly Diagnosed Glioma
Condition: Brain and Central Nervous System Tumors
Intervention: Drug: Erlotinib hydrochloride
25 Completed Cyberknife Precision Radiation Delivery System for Tumors of the Spine
Conditions: Spinal Cord Cancer;   Brain (Nervous System) Cancers
Intervention: Procedure: Stereotactic radiosurgery
26 Completed Phase 1 Intrathecal Topotecan for Neoplastic Meningitis
Condition: Neoplastic Meningitis
Intervention: Drug: Topotecan
27 Completed DepoCyt Therapy in Patients With Neoplastic Meningitis From Lymphoma or a Solid Tumor
Condition: Meningeal Neoplasms
Interventions: Drug: Intrathecal (injected into the spinal fluid) DepoCyt;   Drug: Intrathecal methotrexate;   Drug: Intrathecal cytarabine (also known as ara-C)
28 Recruiting Risk-Adapted Therapy for Young Children With Embryonal Brain Tumors, Choroid Plexus Carcinoma, High Grade Glioma or Ependymoma
Condition: Brain and Central Nervous System Tumors
Interventions: Drug: Induction Chemotherapy;   Drug: Low-Risk Therapy;   Drug: High-Risk Therapy;   Drug: Intermediate-Risk Therapy
29 Terminated Study Bendamustine Concurrent Whole Brain Radiation Brain Metastases From Solid Tumors
Condition: Brain Metastases
Intervention: Drug: Bendamustine
30 Completed Direct Injection of Alcohol for the Treatment of Spinal Tumors
Conditions: Hemangioma;   Neoplasm Metastasis;   Spinal Neoplasm
Intervention:
31 Active, not recruiting
Has Results 		Donepezil in Treating Young Patients With Primary Brain Tumors Previously Treated With Radiation Therapy to the Brain
Conditions: Brain and Central Nervous System Tumors;   Cognitive/Functional Effects;   Long-term Effects Secondary to Cancer Therapy in Children;   Neurotoxicity;   Psychosocial Effects of Cancer and Its Treatment;   Radiation Toxicity
Intervention: Drug: Donepezil
32 Completed SCH 66336 in Treating Children With Recurrent or Progressive Brain Tumors
Condition: Brain and Central Nervous System Tumors
Intervention: Drug: lonafarnib
33 Completed Alpha-Lipoic Acid in Preventing Peripheral Neuropathy in Patients Receiving Chemotherapy for Cancer
Conditions: Neurotoxicity;   Unspecified Adult Solid Tumor, Protocol Specific;   Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: Drug: alpha-lipoic acid;   Other: placebo
34 Recruiting Dose Escalation/De-escalation Study of Pre-operative Stereotactic Radiosurgery for Brain Metastases(RAD 1002)
Condition: Brain Metastases
Intervention: Radiation: Stereotactic Radiosurgery
35 Recruiting A Trial of Poly-ICLC in the Management of Recurrent Pediatric Low Grade Gliomas
Condition: Brain Tumors
Intervention: Drug: Poly ICLC
36 Recruiting Eligibility Screening for a NCI Pediatric Oncology Branch Research Study
Condition: Neoplasm
Intervention:
37 Active, not recruiting
Has Results 		Bevacizumab and Irinotecan in Treating Young Patients With Recurrent, Progressive, or Refractory Glioma, Medulloblastoma, Ependymoma, or Low Grade Glioma
Condition: Brain and Central Nervous System Tumors
Interventions: Biological: bevacizumab;   Drug: irinotecan hydrochloride
38 Completed Cyproheptadine and Megestrol in Preventing Weight Loss in Children With Cachexia Caused By Cancer or Cancer Treatment
Conditions: Brain Tumor;   Central Nervous System Tumors;   Cachexia;   Leukemia;   Lymphoma;   Myelodysplastic Syndromes;   Myelodysplastic/Myeloproliferative Diseases;   Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: Drug: cyproheptadine hydrochloride;   Drug: megestrol acetate
39 Terminated (11C)dLop as a Marker of P-Glycoprotein Function in Patients With Gliomas
Conditions: Low Grade Glioma;   Glioblastoma Multiforme;   Anaplastic Astrocytoma;   Anaplastic Oligodendroglioma;   Oligoastrocytoma
Intervention:
40 Terminated MK0752 in Treating Young Patients With Recurrent or Refractory CNS Cancer
Condition: Brain and Central Nervous System Tumors
Intervention: Drug: MK-0752
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† Indicates status has not been verified in more than two years