124 studies found for:    Brain and Spinal Tumors
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Rank Status Study
21 Active, not recruiting
Has Results
Donepezil in Treating Young Patients With Primary Brain Tumors Previously Treated With Radiation Therapy to the Brain
Conditions: Brain and Central Nervous System Tumors;   Cognitive/Functional Effects;   Long-term Effects Secondary to Cancer Therapy in Children;   Neurotoxicity;   Psychosocial Effects of Cancer and Its Treatment;   Radiation Toxicity
Intervention: Drug: Donepezil
22 Recruiting MyChoice: An Application of the TFEQ-R18v2
Condition: Central Nervous System Neoplasms
Interventions: Behavioral: Three-Factor Eating Questionnaire (TFEQ)-R18v2;   Behavioral: Multifactor Screener;   Behavioral: Eating Questionnaire-EMA (EQ-EMA)
23 Recruiting Prospective Trial for the Diagnosis and Treatment of Intracranial Germ Cell Tumors
Condition: Intracranial Germ Cell Tumors
Interventions: Radiation: craniospinal irradiation;   Drug: Carboplatin, Etoposide, Ifosfamide;   Radiation: ventricular irradiation;   Drug: Cisplatin, etoposide, Ifosfamide (standard);   Drug: Cisplatin, Etoposide, Ifosfamide (high dose);   Radiation: focal irradiation
24 Active, not recruiting Vorinostat, Temozolomide, or Bevacizumab in Combination With Radiation Therapy Followed by Bevacizumab and Temozolomide in Young Patients With Newly Diagnosed High-Grade Glioma
Conditions: Childhood High-grade Cerebellar Astrocytoma;   Childhood High-grade Cerebral Astrocytoma;   Childhood Spinal Cord Neoplasm;   Untreated Childhood Brain Stem Glioma;   Untreated Childhood Cerebral Astrocytoma
Interventions: Drug: vorinostat;   Biological: bevacizumab;   Drug: temozolomide
25 Recruiting Risk-Adapted Therapy for Young Children With Embryonal Brain Tumors, Choroid Plexus Carcinoma, High Grade Glioma or Ependymoma
Condition: Brain and Central Nervous System Tumors
Interventions: Drug: Induction Chemotherapy;   Drug: Low-Risk Therapy;   Drug: High-Risk Therapy;   Drug: Intermediate-Risk Therapy
26 Recruiting Circulating Tumor DNA in Cerebrospinal Fluid as an Early Biomarker of Leptomeningeal Metastasis (LM)
Condition: Leptomeningeal Metastasis
Intervention:
27 Completed Cyproheptadine and Megestrol in Preventing Weight Loss in Children With Cachexia Caused By Cancer or Cancer Treatment
Conditions: Brain Tumor;   Central Nervous System Tumors;   Cachexia;   Leukemia;   Lymphoma;   Myelodysplastic Syndromes;   Myelodysplastic/Myeloproliferative Diseases;   Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: Drug: cyproheptadine hydrochloride;   Drug: megestrol acetate
28 Terminated MK0752 in Treating Young Patients With Recurrent or Refractory CNS Cancer
Condition: Brain and Central Nervous System Tumors
Intervention: Drug: MK-0752
29 Suspended PTC299 in Treating Young Patients With Refractory or Recurrent Primary Central Nervous System Tumors
Condition: Brain and Central Nervous System Tumors
Intervention: Drug: VEGF inhibitor PTC299
30 Completed DepoCyt Therapy in Patients With Neoplastic Meningitis From Lymphoma or a Solid Tumor
Condition: Meningeal Neoplasms
Interventions: Drug: Intrathecal (injected into the spinal fluid) DepoCyt;   Drug: Intrathecal methotrexate;   Drug: Intrathecal cytarabine (also known as ara-C)
31 Completed Alpha-Lipoic Acid in Preventing Peripheral Neuropathy in Patients Receiving Chemotherapy for Cancer
Conditions: Neurotoxicity;   Unspecified Adult Solid Tumor, Protocol Specific;   Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: Drug: alpha-lipoic acid;   Other: placebo
32 Completed Cyberknife Precision Radiation Delivery System for Tumors of the Spine
Conditions: Spinal Cord Cancer;   Brain (Nervous System) Cancers
Intervention: Procedure: Stereotactic radiosurgery
33 Completed Valproic Acid in Treating Young Patients With Recurrent or Refractory Solid Tumors or CNS Tumors
Conditions: Brain and Central Nervous System Tumors;   Unspecified Childhood Solid Tumor, Protocol Specific
Intervention: Drug: valproic acid
34 Withdrawn Talotrexin in Treating Young Patients With Recurrent Solid Tumors or Leukemia That is Recurrent or Does Not Respond to Treatment
Conditions: Brain and Central Nervous System Tumors;   Leukemia;   Lymphoma;   Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: Drug: talotrexin;   Procedure: chemotherapy
35 Recruiting Crizotinib in Treating Young Patients With Relapsed or Refractory Solid Tumors or Anaplastic Large Cell Lymphoma
Conditions: Brain and Central Nervous System Tumors;   Lymphoma;   Neuroblastoma;   Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: Drug: crizotinib;   Other: pharmacogenomic studies;   Other: pharmacological study
36 Active, not recruiting Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid Tumors
Conditions: Brain and Central Nervous System Tumors;   Childhood Germ Cell Tumor;   Extragonadal Germ Cell Tumor;   Kidney Cancer;   Liver Cancer;   Lymphoma;   Neuroblastoma;   Ovarian Cancer;   Sarcoma;   Testicular Germ Cell Tumor;   Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: Drug: carboplatin;   Drug: dasatinib;   Drug: etoposide phosphate;   Drug: ifosfamide;   Genetic: microarray analysis;   Genetic: western blotting;   Other: immunohistochemistry staining method;   Other: laboratory biomarker analysis;   Procedure: therapeutic conventional surgery;   Radiation: radiation therapy
37 Terminated Study Bendamustine Concurrent Whole Brain Radiation Brain Metastases From Solid Tumors
Condition: Brain Metastases
Intervention: Drug: Bendamustine
38 Completed Chemotherapy and Radiation Therapy After Surgery in Treating Children With Newly Diagnosed Astrocytoma, Glioblastoma Multiforme, Gliosarcoma, or Diffuse Intrinsic Pontine Glioma
Condition: Brain and Central Nervous System Tumors
Interventions: Drug: temozolomide;   Procedure: adjuvant therapy;   Radiation: radiation therapy
39 Unknown  Polyvinylpyrrolidone-Sodium Hyaluronate Gel in Reducing Pain From Oral Mucositis in Young Patients With Cancer
Conditions: Brain and Central Nervous System Tumors;   Chordoma;   Kidney Cancer;   Leukemia;   Lymphoma;   Mucositis;   Neuroblastoma;   Pain;   Sarcoma;   Unspecified Childhood Solid Tumor, Protocol Specific
Intervention: Drug: polyvinylpyrrolidone-sodium hyaluronate gel
40 Unknown  Combination Chemotherapy and Radiation Therapy With or Without Methotrexate in Treating Young Patients With Newly Diagnosed Gliomas
Condition: Brain and Central Nervous System Tumors
Interventions: Drug: cisplatin;   Drug: etoposide;   Drug: ifosfamide;   Drug: lomustine;   Drug: methotrexate;   Drug: prednisone;   Drug: vincristine sulfate

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Indicates status has not been verified in more than two years