26 studies found for:    Alpers' Disease
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Rank Status Study
1 Recruiting Prehospital Resuscitation Intranasal Cooling Effects Seen in Magnetic Resonance Imaging of the Brain After Cardiac Arrest
Condition: Cardiac Arrest
Intervention:
2 Recruiting Open-Label, Dose-Escalating Study to Assess Safety, Tolerability, Efficacy, PK and PD of RP103 in Children With Inherited Mitochondrial Disease
Condition: Inherited Mitochondrial Disease, Including Leigh Syndrome
Intervention: Drug: Cysteamine Bitartrate Delayed-release Capsules (RP103)
3 Recruiting North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)
Conditions: Mitochondrial Disorders;   Mitochondrial Genetic Disorders;   Mitochondrial Diseases;   Disorder of Mitochondrial Respiratory Chain Complexes;   Deletion and Duplication of Mitochondrial DNA
Intervention:
4 Active, not recruiting EPI-743 for Mitochondrial Respiratory Chain Diseases
Condition: Mitochondrial Diseases
Intervention: Drug: EPI-743
5 Unknown  Serum Sclerostin Levels, Cardiovascular Parameters and Carpal Tunnel Syndrome in Maintenance Hemodialysis Patients
Conditions: Chronic Kidney Disease;   Renal Osteodystrophy;   Left Ventricular Hypertrophy
Intervention:
6 Terminated
Has Results
Study of Apremilast to Evaluate the Safety and Effectiveness for Patients With Rheumatoid Arthritis
Condition: Rheumatoid Arthritis
Interventions: Drug: Apremilast 30 mg;   Drug: Apremilast 20 mg;   Drug: Placebo
7 Unknown  Mechanisms of Panic Disorders Treatment
Conditions: Panic Disorder;   Agoraphobia;   Panic Attacks
Intervention: Behavioral: Cognitive Behavioural Therapy (CBT)
8 Recruiting Furlow Palatoplasty With Tensor Tenopexy
Conditions: Otitis Media;   Cleft Palate
Intervention: Procedure: palatoplasty
9 Recruiting Safety and Efficacy Study of Apremilast to Treat Psoriatic Arthritis
Condition: Psoriatic Arthritis
Interventions: Drug: Apremilast 30 mg;   Drug: Placebo
10 Active, not recruiting Middle Ear Pressure Disregulation in Cleft Palate Patients
Condition: Cleft Palate
Intervention:
11 Recruiting Balloon Dilation in Selected Subjects With Refractory Eustachian Tube Dysfunction
Condition: Eustachian Tube Dysfunction
Intervention: Procedure: Balloon dilation of the Eustachian tube
12 Unknown  Fibroblast Growth Factor-23 (FGF-23) is Independently Associated With Left Ventricular Mass Index (LVMI) and Myocardial Performance Index (MPI) in Haemodialysis Patients
Condition: Fibroblast
Intervention:
13 Unknown  The Role of FGF23 and Asymmetric Dimethylarginine (ADMA) in Chronic Kidney Disease
Conditions: Metabolic Diseases;   Chronic Kidney Disease
Intervention:
14 Recruiting TransMEM Gas Exchange -- Project 1, Aim 2
Conditions: Middle Ear Disease;   Nasal Allergy
Interventions: Biological: ragweed;   Biological: histamine;   Drug: pseudoephedrine;   Drug: Oxymetazoline
15 Recruiting Gas Supply, Demand and Middle Ear Gas Balance -- Diagnosis of Eustachian Tube Dysfunction
Condition: Eustachian Tube Dysfunction
Interventions: Other: ET Stress test;   Other: Sonotubometry;   Other: Forced Response Test (FRT);   Other: Inflation Deflation Test (IDT);   Other: Maneuver Sequence;   Other: 9-Step Test;   Other: Tubomanometry;   Other: Videoendoscopic assessment of ETF;   Other: Pressure chamber ET test
16 Recruiting A Comparison of the Perioperative Hemodynamic Effects of Remifentanil and Esmolol in Intracranial Surgery
Conditions: Tachycardia;   Hypertension;   Myocardial Ischemia
Interventions: Drug: Esmolol;   Drug: Remifentanil
17 Recruiting Adherence in Pediatric Multiple Sclerosis
Condition: Multiple Sclerosis
Interventions: Behavioral: Motivational Interview;   Other: Video Attention Control
18 Recruiting Trans-Middle-Ear Mucosal Gas Exchange Project 1, Specific Aim 1
Condition: Middle Ear Gas Exchange
Interventions: Drug: 6%CO2, 25%O2, balance N2;   Drug: 6% CO2, 0%O2, balance N2;   Drug: 20%CO2, 6%O2, balance N2;   Drug: 0%CO2, 6%O2, balance N2;   Drug: 6% CO2, 6%O2, balance N2;   Drug: 6%CO2, 6%O2, 0%N2, balance argon
19 Not yet recruiting Gas Supply, Demand and Middle Ear Gas Balance: Specific Aim 3
Condition: Middle-ear Function
Interventions: Other: varied middle-ear pressure;   Drug: varied middle-ear gas composition;   Other: varied ear-canal pressure
20 Recruiting Eustachian Tube Function and Myringoplasty/Tympanoplasty
Condition: Tympanic Membrane Perforation
Intervention: Other: Eustachian tube function testing

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Indicates status has not been verified in more than two years