25 studies found for:    AMG479
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AMG479 (25 records)
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Rank Status Study
1 Completed Study of AMG 479 With Biologics or Chemotherapy for Subjects With Advanced Solid Tumors
Conditions: Advanced Malignancy;   Advanced Solid Tumors;   Cancer;   Solid Tumors;   Tumors
Intervention: Drug: AMG 479
2 Recruiting Open Label Extension Study of Conatumumab and AMG 479
Conditions: Advanced Solid Tumors;   Carcinoid;   Colorectal Cancer;   Locally Advanced;   Lymphoma;   Metastatic Cancer;   Non-Small Cell Lung Cancer;   Sarcoma;   Solid Tumors
Interventions: Drug: FOLFOX6;   Biological: Conatumumab;   Biological: Ganitumab;   Biological: Bevacizumab
3 Terminated Phase 1b/2 Study of AMG 479 in Combination With Paclitaxel and Carboplatin for 1st Line Treatment of Advanced Squamous Non-Small Cell Lung Cancer
Condition: Advanced Squamous Non-Small Cell Lung Cancer
Interventions: Biological: AMG 479;   Drug: Carboplatin;   Drug: Paclitaxel
4 Recruiting A Trial of AMG 479, Everolimus (RAD001) and Panitumumab in Patients With Advanced Cancer
Condition: Advanced Solid Tumors, Non-small Cell Lung Cancer
Intervention: Drug: AMG 479, Everolimus, Panitumumab
5 Recruiting Study of RAD001 + AMG479 for Patients With Advanced Solid Tumors
Condition: Neoplasm Metastases
Intervention: Drug: RAD001 + AMG479
6 Terminated Gemcitabine and AMG 479 in Metastatic Adenocarcinoma of the Pancreas
Conditions: Adenocarcinoma of the Pancreas;   Advanced Solid Tumors;   Cancer;   Cancer of Pancreas;   Cancer of the Pancreas;   Metastases;   Metastatic Cancer;   Metastatic Pancreatic Cancer;   Pancreas Cancer;   Pancreatic Cancer;   Bone Metastases;   Endocrine Cancer;   Oncology;   Oncology Patients;   Solid Tumors;   Advanced Malignancy
Interventions: Drug: AMG 479;   Drug: Placebo;   Drug: gemcitabine
7 Completed Panitumumab Combination Study With AMG 102 or AMG 479 in Wild-type KRAS mCRC
Conditions: Colon Cancer;   Colorectal Cancer;   Gastrointestinal Cancer;   Metastatic Colorectal Cancer;   Rectal Cancer
Interventions: Drug: Panitumumab + AMG 102;   Drug: Panitumumab + AMG 479;   Drug: AMG 479;   Drug: AMG 102;   Drug: Panitumumab
8 Terminated AMG 655 in Combination With AMG 479 in Advanced, Refractory Solid Tumors
Conditions: Colorectal Cancer;   Locally Advanced;   Metastatic Cancer;   Non-Small Cell Lung Cancer;   Ovarian Cancer;   Pancreatic Cancer;   Sarcoma;   Solid Tumors
Interventions: Biological: AMG 479;   Biological: AMG 655
9 Completed A Phase 1b/2 Trial of AMG 479 or AMG 102 in Combination With Platinum-based Chemotherapy as First-Line Treatment for Extensive Stage Small Cell Lung Cancer
Conditions: Lung Cancer;   Small Cell Lung Cancer;   Solid Tumors;   Extensive-stage Small Cell Lung Cancer
Interventions: Drug: AMG 479 in combination with Cisplatin/Etoposide;   Drug: AMG 479 in combination with Carboplatin/Etoposide;   Drug: Placebo in combination with Cisplatin/Etoposide;   Drug: AMG 102 in combination with Cisplatin/Etoposide;   Drug: Placebo in combination with Carboplatin/Etoposide;   Drug: AMG 102 in combination with Carboplatin/Etoposide
10 Active, not recruiting AMG 479 in Advanced Carcinoid and Pancreatic Neuroendocrine Tumors
Conditions: Neuroendocrine Tumor;   Carcinoid Tumor;   Pancreatic Neuroendocrine Tumor
Intervention: Drug: AMG 479
11 Recruiting A Phase Ib/II Study of the Combination of BYL719 Plus AMG 479 in Adult Patients With Selected Solid Tumors
Conditions: PIK3CA Mutated Advanced Solid Tumors,;   PIK3CA Amplified Advanced Solid Tumors
Interventions: Drug: BYL719;   Drug: AMG 479
12 Completed A Phase 2 Study of AMG 479 in Relapsed or Refractory Ewing's Family Tumor and Desmoplastic Small Round Cell Tumors
Conditions: Askin's Tumors;   Desmoplastic Small Round Cell Tumors;   Estraosseous Ewing's Tumor;   Ewing's Family Tumor;   Ewing's Sarcoma;   Primitive Neuroectodermal Tumors (PNETs);   Sarcoma
Intervention: Drug: AMG 479
13 Active, not recruiting A Study of MEK162 and AMG 479 in Patients With Selected Solid Tumors
Conditions: KRAS Mutated Colorectal Adenocarcinoma.;   Metastatic Pancreatic Adenocarcinoma;   BRAF Mutated Melanoma
Intervention: Drug: MEK162 + AMG 479
14 Withdrawn Trastuzumab in Combination With AMG 479 in HER-2 Overexpressing MBC Progressing on Trastuzumab
Condition: Breast Cancer
Interventions: Drug: AMG 479;   Drug: Trastuzumab
15 Completed A Study of AMG 655 or AMG 479 in Combination With Gemcitabine for Treatment of Metastatic Pancreatic Cancer
Conditions: Adenocarcinoma of the Pancreas;   Metastatic Pancreatic Cancer;   Pancreatic Cancer
Interventions: Other: Placebo;   Drug: AMG 479;   Drug: AMG 655
16 Completed Safety & Efficacy of FOLFIRI With AMG 479 or AMG 655 vs FOLFIRI Alone in KRAS-mutant Metastatic Colorectal Carcinoma
Condition: Metastatic Colorectal Cancer
Interventions: Other: FOLFIRI;   Biological: AMG 655;   Other: Placebo;   Biological: AMG 479
17 Terminated Ganitumab in Locally Advanced Unresectable Adenocarcinoma of the Pancreas
Conditions: Adenocarcinoma of the Pancreas;   Locally Advanced;   Unresectable
Interventions: Drug: Gemcitabine;   Drug: AMG 479;   Drug: Placebo
18 Completed Ganitumab and Gemcitabine Hydrochloride Followed by Radiation Therapy, Ganitumab, Capecitabine, and Maintenance Therapy in Treating Patients With Locally Advanced Cancer of the Pancreas
Condition: Pancreatic Cancer
Interventions: Biological: ganitumab;   Drug: capecitabine;   Drug: gemcitabine hydrochloride;   Radiation: 3-dimensional conformal radiation therapy
19 Completed Study of AMG 479 as Second Line Therapy in Patients With Recurrent Platinum-sensitive Ovarian Cancer
Condition: Ovarian Neoplasms
Intervention: Biological: AMG 479
20 Completed A Study of AMG 479 With Exemestane or Fulvestrant in Postmenopausal Women With Hormone Receptor Positive Locally Advanced or Metastatic Breast Cancer
Conditions: Breast Cancer;   Breast Tumors;   Metastatic Cancer
Intervention: Drug: AMG 479 or placebo administered with either exemestane or fulvestrant

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Indicates status has not been verified in more than two years