25 studies found for:    AMG479
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21 Completed Ph2 Biomarker (Mechanism of K-ras Dependency) in Wt KRAS Metastatic Colorectal Cancer Patients
Condition: Metastatic Colorectal Cancer
Interventions: Drug: Panitumumab;   Drug: AMG 479;   Drug: Irinotecan
22 Completed AMG-479 in Treating Patients With Advanced Solid Tumors or Non-Hodgkin Lymphoma
Conditions: Lymphoma;   Prostate Cancer;   Sarcoma;   Small Intestine Cancer;   Unspecified Adult Solid Tumor, Protocol Specific
Interventions: Biological: ganitumab;   Other: laboratory biomarker analysis;   Other: pharmacological study;   Procedure: biopsy
23 Recruiting I-SPY 2 TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer
Conditions: Breast Neoplasms;   Breast Cancer;   Breast Tumors
Interventions: Drug: Standard Therapy;   Drug: AMG 386;   Drug: AMG 479 (Ganitumab) plus Metformin;   Drug: MK-2206 with or without Trastuzumab;   Drug: AMG 386 and Trastuzumab;   Drug: T-DM1 and Pertuzumab;   Drug: Pertuzumab and Trastuzumab
24 Completed Ganitumab and Gemcitabine Hydrochloride Followed by Radiation Therapy, Ganitumab, Capecitabine, and Maintenance Therapy in Treating Patients With Locally Advanced Cancer of the Pancreas
Condition: Pancreatic Cancer
Interventions: Biological: ganitumab;   Drug: capecitabine;   Drug: gemcitabine hydrochloride;   Radiation: 3-dimensional conformal radiation therapy
25 Withdrawn Combination Chemotherapy With or Without Ganitumab in Treating Patients With Previously Untreated Metastatic Pancreatic Cancer
Condition: Pancreatic Cancer
Interventions: Biological: ganitumab;   Drug: fluorouracil;   Drug: irinotecan hydrochloride;   Drug: leucovorin calcium;   Drug: oxaliplatin;   Other: placebo;   Other: questionnaire administration

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Indicates status has not been verified in more than two years