76 studies found for:    Open Studies | methadone
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1 Recruiting Methadone in Pediatric Anesthesiology II
Condition: Pain
Interventions: Drug: Group 1- 0.4mg/kg IV methadone HCl;   Drug: Group 2 - 0.5mg/kg IV methadon HCI;   Other: Group 3 - control no methadone
2 Unknown  Compare Methadone Combined With N-Acetyl-Cysteine (NAC) and Methadone Alone for Opioids Astaining
Condition: Opioids Use
Interventions: Drug: Methadone; NAC;   Drug: Methadone
3 Recruiting CYP2B6 Polymorphisms in Methadone
Condition: Healthy Volunteers
Interventions: Drug: racemic methadone HC1;   Drug: Oral deuterated racemic methadone HCl,
4 Unknown  Methadone Versus Morphine for Orthopedic Surgery Patients
Conditions: Fracture;   Pain, Postoperative
Interventions: Drug: Methadone;   Drug: Morphine
5 Recruiting The Use of Methadone in Newborn Infants
Conditions: Premature Birth of Newborn;   Critically Ill
Intervention: Drug: Methadone
6 Recruiting Methadone vs Magnesium in Spinal Fusion
Condition: Idiopathic Scoliosis
Interventions: Drug: Methadone hydrochloride;   Drug: Magnesium Sulfate;   Drug: Remifentanil
7 Recruiting Treatment of Pain in Head-and-Neck Cancer Patients: is Methadone More Effective?
Conditions: Pain;   Cancer of Head and Neck
Interventions: Drug: fentanyl;   Drug: methadone
8 Recruiting Conversion From Parenteral to Oral Methadone.
Condition: Pain
Interventions: Drug: Parenteral /oral methadone ratio 1:2;   Drug: Parenteral /oral methadone ratio 1:1.2
9 Unknown  Perioperative Opioid-induced Hyperalgesia and Its Prevention With Ketamine and Methadone
Conditions: Post Operative Pain;   Hyperalgesia
Interventions: Drug: ketamine infusion;   Drug: Methadone PCA
10 Recruiting Efficacy Methadone for Management Postoperative Pain After the Use of Anesthesia Intravenous in Laparoscopic Cholecystectomy
Condition: Pain, Postoperative
Interventions: Drug: Morphine;   Drug: Methadone;   Drug: TIVA
11 Recruiting Evaluation of the Efficacy and Safety of Two Methadone Titration Methods for the Treatment of Cancer-related Pain With Inadequate Pain Relief or Intolerable Side Effects When Treated With Level 3 Opioids.
Condition: Pain Related to Cancer
Intervention: Drug: Methadone
12 Recruiting Methadone in Pediatric and Adult Sickle Cell Patients
Condition: Sickle Cell Disease
Interventions: Drug: Morphine;   Drug: Methadone
13 Unknown  Switching From Morphine to Oral Methadone Plus Acetaminophen in the Treatment of Cancer Pain
Conditions: Cancer;   Pain;   Palliative Care
Intervention: Drug: Methadone plus Acetaminophen or Placebo
14 Not yet recruiting A Prospective Comparison of Methadone, Fentanyl, and Morphine for Post-laparotomy Epidural Analgesia
Condition: Post Laparotomy Pain Treatment
Interventions: Drug: epidural morphine via PCEA;   Drug: epidural fentanyl via PCEA;   Drug: epidural methadone via PCEA;   Drug: intravenous morphine via PCA
15 Recruiting Pupillometry and Pain Thresholds Patients Substituted by Methadone and Buprenorphine
Conditions: Opiate Dependent;   Previous Illicit Drug Use
Intervention: Drug: Buprenorphine and Methadone Hydrochloride
16 Recruiting Methadone and Hydromorphone For Spinal Surgery
Conditions: Hydromorphone Use;   Acute Postoperative Pain;   Patient Satisfaction;   Chronic Persistent Surgical Pain
Interventions: Drug: Methadone;   Drug: Hydromorphone
17 Recruiting Improving Outcomes in Neonatal Abstinence Syndrome
Conditions: Neonatal Abstinence Syndrome;   Neonatal Opioid Withdrawal
Interventions: Drug: Neonatal Morphine Solution;   Drug: Methadone;   Drug: Phenobarbital
18 Unknown  Efficacy & Safety Study of Nonracemic Methadone for the Relief of Chronic Peripheral Neuropathic Pain
Condition: Diabetic Peripheral Neuropathic Pain
Intervention: Drug: Non-racemic mixture of methadone HCl
19 Recruiting Pharmacokinetics of Multiple Dose Methadone in Children Treated for Opiate Withdrawal
Condition: Opiate Withdrawal Syndrome
Intervention: Drug: Methadone
20 Unknown  QTc and Perceived Sleep Follow up Among Chronic Pain Patients With Opiate Medication
Condition: Chronic Pain
Intervention: Drug: Methadone

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