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1062 studies found for:    Open Studies | "Antineoplastic Agents, Alkylating"
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Rank Status Study
1 Recruiting Post-transplantation Cyclophosphamide as GVHD Prophylaxis After HSCT
Conditions: Acute Myeloid Leukemia;   Acute Lymphoid Leukemia;   Lymphoma;   Myelodysplastic Syndromes;   Chronic Lymphocytic Leukemia;   Immune System Diseases
Interventions: Drug: Cyclophosphamide;   Drug: Busulfan;   Drug: Fludarabine monophosphate;   Drug: Tacrolimus;   Drug: Mycophenolate mofetil;   Procedure: Allogeneic hematopoietic stem cell transplantation
2 Recruiting Randomized Study of Combination Chemotherapy With or Without Focused Microwave Thermotherapy Before Surgery in Treating Women With Large Breast Cancer Tumors
Condition: Breast Cancer
Interventions: Device: Focused Microwave Thermotherapy;   Drug: Chemotherapy (control)
3 Recruiting Lenalidomide vs Placebo Maintenance Therapy Following Melphalan Prednisone Velcade® Induction Therapy in NDMM
Condition: Multiple Myeloma
Interventions: Drug: Lenalidomide;   Drug: Placebo
4 Not yet recruiting A Phase II Trial of Oncolytic Virotherapy by Systemic Administration of Edmonston Strain of Measles Virus
Condition: Multiple Myeloma
Intervention: Drug: MV-NIS
5 Recruiting Multidisciplinary Approach for Poor Prognosis Sinonasal Tumors in Operable Patients
Condition: Sinonasal Tumors
Interventions: Drug: Cisplatin;   Drug: Docetaxel;   Drug: 5-fluorouracil;   Drug: Etoposide;   Drug: Adriamycin;   Drug: Ifosfamide;   Drug: Leucovorin;   Radiation: Radiotherapy - Patients needing Elective Nodal Volume (ENI);   Radiation: Radiotherapy - Patients not needing ENI;   Radiation: Radiotherapy - Patients needing curative neck irradiation
6 Recruiting Sirolimus With Cyclophosphamide and Topotecan for Pediatric/Adolescent Relapsed and Refractory Solid Tumors
Conditions: Malignant Solid Tumor;   Childhood Solid Tumor
Intervention: Drug: Sirolimus, Cyclophosphamide, Topotecan
7 Recruiting Study of IPI-145 in Combination With Bendamustine, Rituximab or Bendamustine/Rituximab in Hematologic Malignancies
Conditions: Lymphoma;   Chronic Lymphocytic Leukemia;   Non-Hodgkin Lymphoma;   T-cell Lymphoma
Interventions: Drug: IPI-145;   Drug: Rituximab;   Drug: Bendamustine
8 Recruiting SCD-Haplo: A Phase II Study of HLA-Haploidentical Stem Cell Transplantation to Treat Clinically Aggressive Sickle Cell Disease
Condition: Sickle Cell Disease
Interventions: Procedure: Haploidentical Transplant;   Drug: Alemtuzumab;   Radiation: Total Body Irradiation;   Drug: Cyclophosphamide;   Drug: Sirolimus
9 Recruiting Temozolomide With or Without Capecitabine in Treating Patients With Advanced Pancreatic Neuroendocrine Tumors
Conditions: Gastrinoma;   Glucagonoma;   Insulinoma;   Islet Cell Carcinoma;   Pancreatic Polypeptide Tumor;   Recurrent Islet Cell Carcinoma;   Somatostatinoma
Interventions: Drug: temozolomide;   Drug: capecitabine;   Other: laboratory biomarker analysis
10 Recruiting Study to Compare Busulfan-fludarabine With Thiotepa-fludarabine Regimen in Allogeneic Transplantation for Myelofibrosis
Condition: Myelofibrosis
Interventions: Drug: A: Fludarabine + Busulphan;   Drug: B: Fludarabine + Thiotepa
11 Not yet recruiting Intravenous Chemotherapy or Oral Chemotherapy in Treating Patients With Previously Untreated Stage III-IV HIV-Associated Non-Hodgkin Lymphoma
Conditions: AIDS-related Diffuse Large Cell Lymphoma;   AIDS-related Diffuse Mixed Cell Lymphoma;   AIDS-related Diffuse Small Cleaved Cell Lymphoma;   AIDS-related Immunoblastic Large Cell Lymphoma;   AIDS-related Lymphoblastic Lymphoma;   AIDS-related Peripheral/Systemic Lymphoma;   AIDS-related Small Noncleaved Cell Lymphoma;   Stage III AIDS-related Lymphoma;   Stage IV AIDS-related Lymphoma
Interventions: Drug: cyclophosphamide;   Drug: doxorubicin hydrochloride;   Drug: vincristine sulfate;   Drug: prednisone;   Drug: lomustine;   Drug: etoposide;   Drug: procarbazine hydrochloride;   Other: laboratory biomarker analysis
12 Unknown  Bevacizumab and Trastuzumab With Weekly Paclitaxel Followed, After Surgery, by Encapsuled Liposomal Doxorubicin, Cyclophosphamide and Trastuzumab as Adjuvant Treatment After Surgery on Women With Her2+ Breast Cancer
Condition: Breast Cancer
Intervention: Drug: Bevacizumab,Trastuzumab,Paclitaxel,Cyclophosphamide,Myocet
13 Recruiting Temozolomide Plus Endostatin in Advanced Pancreatic Neuroendocrine Tumor
Condition: Advanced Well-differentiated Pancreatic Neuroendocrine Tumor
Intervention: Drug: temozolomide combined with endostatin
14 Recruiting Targeted Busulfan, Fludarabine Conditioning Regimen for Hematopoietic Stem Cell Transplantation in Chronic Granulomatous Disease(CGD)
Condition: Chronic Granulomatous Disease
Intervention: Drug: Busulfan
15 Recruiting Trabectedin First Line Therapy In Unfit Sarcoma Study
Conditions: Metastatic and Locally Advanced Soft Tissue Tumor Patients Unfit to Receive;   Standard Chemotherapy
Intervention: Drug: Trabectedin
16 Recruiting Phase II Trial of Low-Dose Whole Brain Radiotherapy With Concurrent Temozolomide and Adjuvant Temozolomide in Patients With Newly-Diagnosed Glioblastoma Multiforme
Condition: Histologically Proven Diagnosis of Glioblastoma or Gliosarcoma (WHO Grade IV)
Interventions: Drug: Chemotherapy with Temodar.;   Radiation: Radiation therapy
17 Recruiting LAL-BR/2001: Study Treatment to Low Risk ALL
Condition: Acute Lymphoblastic Leukemia
Interventions: Drug: Prednisone;   Drug: Vincristine;   Drug: Daunorubicin;   Drug: L-Asparaginase;   Drug: Cyclophosphamide;   Drug: Methotrexate;   Drug: Cytosine Arabinoside;   Drug: Mercaptopurine;   Drug: VP-16
18 Not yet recruiting Efficacy and Safety of Idelalisib in Combination With Obinutuzumab Compared to Chlorambucil in Combination With Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia
Condition: Chronic Lymphocytic Leukemia
Interventions: Drug: Idelalisib;   Drug: Chlorambucil;   Drug: Obinutuzumab
19 Recruiting the Effects and Safety of Idarubicin-strengthened Pretreatment Program and Conventional Busulfan Cyclophosphamide Pretreatment Program on High-risk Acute Myeloid Leukemia Patient
Condition: Acute Myeloid Leukemia
Intervention: Drug: Cyclosporin A,mycophenolate mofetil,Methotrexate
20 Recruiting Carfilzomib, Cyclophosphamide and Dexamethasone In Newly Diagnosed Multiple Myeloma Patients
Condition: Multiple Myeloma

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