205 studies found for:    Open Studies | "Triplets"
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21 Recruiting A Phase II Study of the Aurora and Angiogenic Kinase Inhibitor ENMD-2076 in Previously Treated Locally Advanced and Metastatic Triple-Negative Breast Cancer
Condition: Triple Negative Breast Cancer
Intervention: Drug: ENMD-2076
22 Recruiting Cediranib Maleate and Olaparib in Treating Patients With Recurrent Ovarian, Fallopian Tube, Peritoneal Cancer, or Triple-Negative Breast Cancer
Conditions: Estrogen Receptor-negative Breast Cancer;   HER2-negative Breast Cancer;   Ovarian Endometrioid Adenocarcinoma;   Ovarian Papillary Serous Carcinoma;   Ovarian Serous Cystadenocarcinoma;   Progesterone Receptor-negative Breast Cancer;   Recurrent Breast Cancer;   Recurrent Fallopian Tube Cancer;   Recurrent Ovarian Epithelial Cancer;   Recurrent Primary Peritoneal Cavity Cancer;   Triple-negative Breast Cancer
Interventions: Drug: olaparib;   Drug: cediranib maleate;   Other: laboratory biomarker analysis
23 Recruiting BRCA1-associated DNA Repair Dysfunction in Patients With Early Triple Negative Breast Cancer Treated With Neoadjuvant Platinum-based Chemotherapy
Condition: Early Triple Negative Breast Cancer
Intervention: Drug: Doxorubicin, Paclitaxel, Cisplatin
24 Recruiting Randomized Controlled Trial of Genomically Directed Therapy in Patients With Triple Negative Breast Cancer
Conditions: Triple Negative (ER-/PR-/HER2-) Invasive Breast Cancer;   Breast Cancer
Interventions: Drug: Genomically Directed Monotherapy;   Other: Observation/Standard Therapy
25 Recruiting Capecitabine + BKM120 TNBC BC Brain Met
Conditions: Triple Negative Breast Cancer;   Brain Metastases;   Breast Cancer
Interventions: Drug: BKM120;   Drug: capecitabine
26 Recruiting AZD8186 First Time In Patient Ascending Dose Study
Conditions: Advanced Castrate-resistant Prostate Cancer (CRPC);;   Squamous Non-Small Cell Lung Cancer (sqNSCLC);;   Triple Negative Breast Cancer (TNBC)
Intervention: Drug: AZD8186
27 Recruiting Triple-B Study;Carboplatin-cyclophosphamide Versus Paclitaxel With or Without Bevacizumab as First-line Treatment in Advanced Triple Negative Breast Cancer
Condition: Breast Cancer
Interventions: Drug: Carbo/cyclo;   Drug: Carbo/cyclo + bevacizumab;   Drug: Paclitaxel;   Drug: Paclitaxel + Bevacizumab
28 Recruiting Paclitaxel Albumin-Stabilized Nanoparticle Formulation and Bevacizumab Followed By Bevacizumab and Erlotinib Hydrochloride in Treating Patients With Metastatic Breast Cancer
Conditions: Estrogen Receptor-negative Breast Cancer;   HER2-negative Breast Cancer;   Progesterone Receptor-negative Breast Cancer;   Recurrent Breast Cancer;   Stage IV Breast Cancer;   Triple-negative Breast Cancer
Interventions: Drug: paclitaxel albumin-stabilized nanoparticle formulation;   Biological: bevacizumab;   Drug: erlotinib hydrochloride;   Other: laboratory biomarker analysis
29 Recruiting Carboplatin and Combination Chemotherapy With or Without Veliparib in Treating Patients With Stage IIB-IIIC Breast Cancer
Conditions: Estrogen Receptor-negative Breast Cancer;   HER2-negative Breast Cancer;   Progesterone Receptor-negative Breast Cancer;   Stage II Breast Cancer;   Stage IIIA Breast Cancer;   Stage IIIB Breast Cancer;   Stage IIIC Breast Cancer;   Triple-negative Breast Cancer
Interventions: Drug: Paclitaxel;   Drug: Carboplatin;   Drug: Doxorubicin;   Drug: Cyclophosphamide;   Drug: Veliparib
30 Not yet recruiting Therapeutic Efficacy of Triple Combination in Drug-naïve Korean Type 2 Diabetic Patients
Condition: Type 2 Diabetic
Intervention: Drug: Triple combination
31 Recruiting X-chromosome Inactivation, Epigenetics and the Transcriptome
Conditions: Turner Syndrome;   Klinefelter Syndrome;   Triple X Syndrome;   47 XYY Syndrome;   Aortic Aneurysm
32 Recruiting An Open-Label, Multicenter, Phase 1/2 Study of Poly(ADP-Ribose) Polymerase (PARP) Inhibitor E7449 as Single Agent in Subjects With Advanced Solid Tumors or With B-cell Malignancies and in Combination With Temozolomide (TMZ) or With Carboplatin and Paclitaxel in Subjects With Advanced Solid Tumors
Conditions: Malignant Solid Tumour;   Ovarian Cancer;   Triple Negative Breast Cancer;   Advanced Melanoma;   B-cell Malignancy, Low-grade
Interventions: Drug: E7449 alone;   Drug: E7449 plus TMZ;   Drug: E7449 plus carboplatin and paclitaxel
33 Recruiting Pilot Study to Determine Biodistribution of MM-398 and Feasibility of Ferumoxytol as a Tumor Imaging Agent
Conditions: Solid Tumors;   Triple Negative Breast Cancer;   Non Small Cell Lung Cancer;   Colorectal Cancer;   ER/PR Positive Breast Cancer;   Pancreatic Cancer;   Ovarian Cancer;   Gastric Cancer;   Gastro-Esophageal Junction Adenocarcinoma;   Head and Neck Cancer
Intervention: Drug: Ferumoxytol followed by MM-398
34 Recruiting A Study of Oral LGK974 in Patients With Malignancies Dependent on Wnt Ligands
Conditions: Melanoma;   Breast Neoplasms;   Lobular Carcinoma;   Triple-negative Breast Cancer;   Pancreatic Adenocarcinoma;   Colorectal Cancer;   Head and Neck Cancer;   Other Tumor Types With Documented Genetic Alterations Upstream in the Wnt Signaling Pathway
Intervention: Drug: LGK974
35 Recruiting Phase Ib, Dose Escalation Study of Oral LDE225 in Combination With BKM120 in Patients With Advanced Solid Tumors
Conditions: Dose Escalation;   Safety;   Preliminary Efficacy;   Advanced Solid Tumors;   Metastatic Breast Cancer;   Advanced Pancreatic Adenocarcinoma;   Metastatic Colorectal Cancer;   Recurrent Glioblastoma Multiforme;   Gastric Cancer;   Gastroesophageal Junction Cancer;   Triple Negative Metastatic Breast Cancer;   Hormone Receptor Positive (ER+/PR+, and Her2-) Metastatic Breast Cancer
Interventions: Drug: LDE225;   Drug: BKM120
36 Recruiting eMet CAR RNA T Cells Targeting Breast Cancer
Conditions: Metastatic Breast Cancer;   Triple Negative Breast Cancer
Intervention: Biological: cMet RNA CAR T cells
37 Recruiting Triple Negative Breast Cancer: Study of Molecular and Genetic Factors
Condition: Breast Cancer
Intervention: Genetic: BRCA1 BRCA2 PTEN PALB2 mutation
38 Recruiting BKM120 For Triple Negative Breast Cancer
Condition: Breast Cancer
Intervention: Drug: BKM120
39 Unknown  Modified Triple Osteotomy for Acetabular Dysplasia
Conditions: Sharp Angle;   Center Edge Angle;   Femoral Head Extrusion Index;   Center Head Distance Discrepancy
40 Recruiting Study of Erlotinib and Metformin in Triple Negative Breast Cancer
Condition: Breast Cancer
Interventions: Drug: Metformin;   Drug: Erlotinib

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