210 studies found for:    Open Studies | "Triplets"
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21 Recruiting Cediranib Maleate and Olaparib in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Peritoneal Cancer or Recurrent Triple-Negative Breast Cancer
Conditions: Estrogen Receptor-negative Breast Cancer;   HER2-negative Breast Cancer;   Ovarian Endometrioid Adenocarcinoma;   Ovarian Papillary Serous Carcinoma;   Ovarian Serous Cystadenocarcinoma;   Progesterone Receptor-negative Breast Cancer;   Recurrent Breast Cancer;   Recurrent Fallopian Tube Cancer;   Recurrent Ovarian Epithelial Cancer;   Recurrent Primary Peritoneal Cavity Cancer;   Triple-negative Breast Cancer
Interventions: Drug: olaparib;   Drug: cediranib maleate;   Other: laboratory biomarker analysis
22 Recruiting BRCA1-associated DNA Repair Dysfunction in Patients With Early Triple Negative Breast Cancer Treated With Neoadjuvant Platinum-based Chemotherapy
Condition: Early Triple Negative Breast Cancer
Intervention: Drug: Doxorubicin, Paclitaxel, Cisplatin
23 Recruiting Randomized Controlled Trial of Genomically Directed Therapy in Patients With Triple Negative Breast Cancer
Conditions: Triple Negative (ER-/PR-/HER2-) Invasive Breast Cancer;   Breast Cancer
Interventions: Drug: Genomically Directed Monotherapy;   Other: Observation/Standard Therapy
24 Unknown  Maraviroc (Celsentri) With Raltegravir and Darunavir/Ritonavir for the Treatment of Triple Class Failure in Adult HIV-1 Infected Patients
Conditions: HIV-1 Adults Patients;   AIDS;   Triple Class Failure
Interventions: Drug: maraviroc;   Drug: Raltegravir;   Drug: Darunavir/ritonavir
25 Recruiting Capecitabine + BKM120 TNBC BC Brain Met
Conditions: Triple Negative Breast Cancer;   Brain Metastases;   Breast Cancer
Interventions: Drug: BKM120;   Drug: capecitabine
26 Recruiting AZD8186 First Time In Patient Ascending Dose Study
Conditions: Advanced Castrate-resistant Prostate Cancer (CRPC);;   Squamous Non-Small Cell Lung Cancer (sqNSCLC);;   Triple Negative Breast Cancer (TNBC)
Intervention: Drug: AZD8186
27 Recruiting Paclitaxel Albumin-Stabilized Nanoparticle Formulation and Bevacizumab Followed By Bevacizumab and Erlotinib Hydrochloride in Treating Patients With Metastatic Breast Cancer
Conditions: Estrogen Receptor-negative Breast Cancer;   HER2-negative Breast Cancer;   Progesterone Receptor-negative Breast Cancer;   Recurrent Breast Cancer;   Stage IV Breast Cancer;   Triple-negative Breast Cancer
Interventions: Drug: paclitaxel albumin-stabilized nanoparticle formulation;   Biological: bevacizumab;   Drug: erlotinib hydrochloride;   Other: laboratory biomarker analysis
28 Recruiting Carboplatin and Combination Chemotherapy With or Without Veliparib in Treating Patients With Stage IIB-IIIC Breast Cancer
Conditions: Estrogen Receptor-negative Breast Cancer;   HER2-negative Breast Cancer;   Progesterone Receptor-negative Breast Cancer;   Stage II Breast Cancer;   Stage IIIA Breast Cancer;   Stage IIIB Breast Cancer;   Stage IIIC Breast Cancer;   Triple-negative Breast Cancer
Interventions: Drug: Paclitaxel;   Drug: Carboplatin;   Drug: Doxorubicin;   Drug: Cyclophosphamide;   Drug: Veliparib
29 Recruiting An Open-Label, Multicenter, Phase 1/2 Study of Poly(ADP-Ribose) Polymerase (PARP) Inhibitor E7449 as Single Agent in Subjects With Advanced Solid Tumors or With B-cell Malignancies and in Combination With Temozolomide (TMZ) or With Carboplatin and Paclitaxel in Subjects With Advanced Solid Tumors
Conditions: Malignant Solid Tumour;   Ovarian Cancer;   Triple Negative Breast Cancer;   Advanced Melanoma;   B-cell Malignancy, Low-grade
Interventions: Drug: E7449 alone;   Drug: E7449 plus TMZ;   Drug: E7449 plus carboplatin and paclitaxel
30 Recruiting Pilot Study to Determine Biodistribution of MM-398 and Feasibility of Ferumoxytol as a Tumor Imaging Agent
Conditions: Solid Tumors;   Triple Negative Breast Cancer;   Non Small Cell Lung Cancer;   Colorectal Cancer;   ER/PR Positive Breast Cancer;   Pancreatic Cancer;   Ovarian Cancer;   Gastric Cancer;   Gastro-Esophageal Junction Adenocarcinoma;   Head and Neck Cancer
Intervention: Drug: Ferumoxytol followed by MM-398
31 Recruiting A Study of Oral LGK974 in Patients With Malignancies Dependent on Wnt Ligands
Conditions: Melanoma;   Breast Neoplasms;   Lobular Carcinoma;   Triple-negative Breast Cancer;   Pancreatic Adenocarcinoma;   Colorectal Cancer;   Head and Neck Cancer;   Other Tumor Types With Documented Genetic Alterations Upstream in the Wnt Signaling Pathway
Intervention: Drug: LGK974
32 Recruiting eMet CAR RNA T Cells Targeting Breast Cancer
Conditions: Metastatic Breast Cancer;   Triple Negative Breast Cancer
Intervention: Biological: cMet RNA CAR T cells
33 Recruiting Triple Negative Breast Cancer: Study of Molecular and Genetic Factors
Condition: Breast Cancer
Intervention: Genetic: BRCA1 BRCA2 PTEN PALB2 mutation
34 Recruiting Defining the Triple Negative Breast Cancer Kinome Response to GSK1120212
Condition: Breast Cancer
Intervention: Drug: GSK1120212
35 Recruiting BKM120 For Triple Negative Breast Cancer
Condition: Breast Cancer
Intervention: Drug: BKM120
36 Recruiting Cisplatin + RT for Triple Negative Breast Cancer
Condition: Breast Cancer
Interventions: Radiation: Radiation Therapy;   Drug: Cisplatin
37 Recruiting Study of Erlotinib and Metformin in Triple Negative Breast Cancer
Condition: Breast Cancer
Interventions: Drug: Metformin;   Drug: Erlotinib
38 Recruiting Neo Adjuvant Chemotherapy in Triple Negative Breast Cancer
Condition: Breast Cancer
Interventions: Drug: Carboplatin and Paclitaxel;   Drug: Doxorubicin, cyclophosphamide;   Drug: Doxorubicin, cyclophosphamide, carboplatin, thiotepa, cyclophosphamide
39 Recruiting Triple-B Study;Carboplatin-cyclophosphamide Versus Paclitaxel With or Without Bevacizumab as First-line Treatment in Advanced Triple Negative Breast Cancer
Condition: Breast Cancer
Interventions: Drug: Carbo/cyclo;   Drug: Carbo/cyclo + bevacizumab;   Drug: Paclitaxel;   Drug: Paclitaxel + Bevacizumab
40 Recruiting Efficacy of Capecitabine Metronomic Chemotherapy to Triple-negative Breast Cancer
Condition: Breast Cancer
Interventions: Drug: Capecitabine (Xeloda);   Drug: Standard adjuvant chemotherapy

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