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58 studies found for:    Open Studies | "Thalassemia"

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1 Recruiting Study to Determine the Safety and Tolerability of Sotatercept (ACE-011) in Adults With Beta( β)- Thalassemia.
Conditions: Beta Thalassemia Major;   Beta Thalassemia Intermedia
Intervention: Drug: SOTATERCEPT (ACE-011)
2 Unknown † Beta-thalassemia and Microparticles
Conditions: Thalassemia Major (TM);   Thalassemia Intermedia (TI);   Microparticles (MP)Originating From Platelets, Endothelial Cells and Monocytes
Intervention: Other: Physiopathology
3 Recruiting Allogeneic Stem Cell Transplantation, Severe Homzygous 0/+Thalassemia or Sever Variants of Beta 0/+ Thalassemia, THALLO
Condition: Thalassemia
Interventions: Drug: Busulfan;   Drug: Fludarabine;   Drug: Campath 1H;   Drug: Cyclophosphamide;   Drug: MESNA
4 Unknown † Endocrine and Nutritional Assessment in B Thalassemia Major
Condition: Thalassemia
Intervention: Other: Nutritional recommendations
5 Recruiting Amlodipine in the Prevention and Treatment of Iron Overload in Patients With Thalassemia Major
Conditions: Thalassemia;   Iron Overload
Intervention: Drug: Amlodipine
6 Recruiting Stem Cell Transplant in Sickle Cell Disease and Thalassemia
Conditions: Sickle Cell Disease;   Beta Thalassemia
Interventions: Drug: Busulfan;   Drug: Fludarabine;   Drug: Alemtuzumab;   Procedure: Allogeneic stem cell transplant
7 Unknown † Iron Overload and Growth Velocity in Thalassemia and Sickle Cell Anemia
Conditions: Thalassemia;   Sickle Cell Disease
Intervention: Other: Medical Chart Summary
8 Not yet recruiting The Effect of Vitamin D Supplementation on Calcium Excretion in Thalassemia: a Dose Response Study
Condition: Thalassemia Major
Interventions: Drug: Vitamin D3;   Drug: Placebo
9 Recruiting Combination Deferasirox and Deferiprone for Severe Iron Overload in Thalassemia
Condition: Thalassemia Major With Severe Transfusional Iron Overload
Intervention: Drug: Deferasirox and deferiprone
10 Recruiting Evaluating the Safety and Effectiveness of Mozobil Mobilization in Adults With Beta-Thalassemia Major
Condition: Beta-Thalassemia
Intervention: Drug: Mozobil
11 Recruiting Zinc and Diabetes in Patients With Thalassemia: a Pilot Study
Condition: Thalassemia
Intervention: Dietary Supplement: Zinc Supplementation
12 Unknown † Detection of β Thalassemia Carriers by Red Cell Parameters Obtained From the H2 Automatic Counter
Conditions: Thalassemia;   Iron Deficiency
Intervention: Procedure: Observation of results from laboratory tests
13 Not yet recruiting A Study Evaluating the Safety and Efficacy of the LentiGlobin® BB305 Drug Product in Beta-Thalassemia Major Subjects
Condition: Beta-thalassemia Major
Intervention: Genetic: LentiGlobin® BB305 Drug Product
14 Recruiting An Open Label, Multi-center, Efficacy and Safety Study of Deferasirox in Iron Overloaded Patients With Non-transfusion Dependent Thalassemia
Condition: Non-transfusion Dependent Thalassemia
Intervention: Drug: ICL670 deferasirox
15 Recruiting Genetic Factors Affecting the Severity of Beta Thalassemia
Condition: Beta Thalassemia
Intervention:
16 Unknown † Demographic, Clinical and Laboratory Characteristics of Children With Alpha Thalassemia in Northern Israel
Conditions: Thalassemia Alpha;   Hemolytic Anemia
Intervention: Other: Medical records summary
17 Recruiting Retroviral Vector Mediated Globin Gene Transfer to Correct Sickle Cell Anemia or Thalassemia
Conditions: Sickle Cell Anemia;   Thalassemia
Intervention: Genetic: Gene Therapy
18 Not yet recruiting Study to Evaluate Efficacy and Safety of S303 Treated Red Blood Cells (RBCs)in Subjects With Thalassemia Major Requiring Chronic RBC Transfusion
Condition: Thalassemia Major
Interventions: Biological: S-303 Treated Red Blood Cells (RBCs);   Biological: Conventional, untreated Red Blood Cells
19 Unknown † Factors Promoting Increased Rate and Success of Pregnancy in the Thalassemia Population in Toronto
Conditions: Thalassemia;   Fertility;   Pregnancy
Intervention:
20 Recruiting Safety and Efficacy of Deferasirox in β-thalassaemia Patients With Severe Cardiac Iron Overload
Conditions: Transfusion-dependent β-thalassemia Patients;   Cardiac Iron Overload
Interventions: Drug: Deferasirox;   Drug: Deferasirox + Deferoxamine
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† Indicates status has not been verified in more than two years