47 studies found for:    Open Studies | "Pruritus"
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1 Recruiting Open Label Extension Study of Nalbuphine HCl ER in Hemodialysis Patients With Uremic Pruritus
Conditions: Uremic Pruritus;   Pruritus
Interventions: Drug: nalbuphine HCl ER 60mg BID;   Drug: nalbuphine HCl ER 90mg BID;   Drug: nalbuphine HCl ER 120mg BID
2 Recruiting Study of Nalbuphine HCl ER Tablets in Hemodialysis Patients With Uremic Pruritus
Conditions: Uremic Pruritus;   Pruritus
Interventions: Drug: nalbuphine HCl ER tablets 60 mg BID;   Drug: nalbuphine HCl ER tablets 120mg BID;   Drug: Placebo tablets BID
3 Recruiting Safety and Pharmacokinetics of IV CR845 in Hemodialysis Patients, and Its Efficacy in Patients With Uremic Pruritus
Conditions: Pruritus;   Uremic Pruritus
Interventions: Drug: Part A: Placebo;   Drug: Part A: CR845 0.5 mcg/kg;   Drug: Part A: CR845 1.0 mcg/kg;   Drug: Part A: CR845 2.5 mcg/kg;   Drug: Part B: Placebo;   Drug: Part B: CR845
4 Not yet recruiting Impact of Vorinostat on Pruritus Signaling Pathways - Merck Study
Condition: Pruritus
Interventions: Procedure: Biopsy;   Procedure: Blood
5 Recruiting Effect of Neurokinin-1 Receptor (NK1R) Antagonism on Pruritus in Patients With Sezary Syndrome
Conditions: Sezary Syndrome;   Pruritus
Interventions: Drug: Aprepitant;   Drug: Placebo
6 Recruiting Naloxone for the Treatment of Opioid-Induced Pruritus
Condition: Pruritus
Interventions: Drug: Naloxone;   Drug: Saline/Morphine
7 Unknown  Gabapentin - A Solution to Uremic Pruritus?
Conditions: Pruritus;   Uremia
Intervention: Drug: Gabapentin
8 Unknown  Efficacy of Pregabalin in the Management of Chronic Uremic Pruritus
Condition: Uremic Pruritus
Interventions: Drug: Pregabalin;   Drug: Placebo
9 Not yet recruiting Pregabalin for the Treatment of Uremic Pruritus
Condition: Uremic Pruritus
Interventions: Drug: pregabalin 75mg daily for 12 weeks;   Drug: fexofenadine 60 mg daily for 12 weeks;   Drug: placebo
10 Unknown  A Randomized-Withdrawal Phase 3 Study Evaluating the Safety and Efficacy of Oral Nalfurafine HCl (AC-820)in Subjects on Hemodialysis With Uremic Pruritus (Renal Itch)
Condition: Uremic Pruritus
Interventions: Drug: Nalfurafine HCl 2.5 µg;   Drug: Nalfurafine HCl 5.0 µg;   Other: Placebo
11 Recruiting Proof of Concept of VLY-686 in Subjects With Treatment-Resistant Pruritus Associated With Atopic Dermatitis
Condition: Treatment-resistant Pruritus Associated With Atopic Dermatitis
Interventions: Drug: VLY-686;   Drug: Placebo
12 Recruiting VPD-737 for Treatment of Chronic Pruritus
Condition: Chronic Pruritus
Interventions: Drug: VPD-737;   Drug: Placebo
13 Not yet recruiting Study of Using Long Acting Antihistamine to Treat Opioid Induced Itching
Condition: Pruritus
Interventions: Drug: Cetirizine;   Drug: Placebo or sugar pill
14 Unknown  Treatment of Uremic Pruritus by Olive-omega 3 Ointment
Condition: Uremic Pruritus
Intervention: Procedure: application of ointment (olive-omega 3 ointment)
15 Recruiting Pruritus in Patients With Chronic Kidney Disease
Conditions: Kidney Failure, Chronic;   Pruritus
Intervention: Other: Questionnaire based on the McGill Pain Questionnaire
16 Unknown  Vulvar Contact Dermatitis Resulting From Urine Incontinence
Conditions: Urinary Incontinence;   Vulvar Pruritus;   Vulvar Contact Dermatitis
Intervention: Other: Questionnaires, gynecological exam , vaginal smear, and measurement of urine leakage
17 Recruiting Topical Aprepitant in Prurigo Patients
Condition: Pruritus
Interventions: Drug: Aprepitant;   Drug: Placebo
18 Recruiting Acticoat Absorbent and BCT Antimicrobial for STSG Donor Site on Thigh
Conditions: Wound Healing;   Wound Infection;   Pain;   Pruritus;   Cicatrix
Interventions: Device: Acticoat Absorbent;   Device: BCT
19 Recruiting Prevention of Intrathecal Morphine Induced Pruritus: Comparison of Ondansetron and Palonosetron
Condition: Morphine Adverse Reaction
Interventions: Drug: Ondansetron;   Drug: Palonosetron
20 Recruiting A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of Repeat Doses of GSK2330672 Administration in Subjects With Primary Biliary Cirrhosis (PBC) and Symptoms of Pruritus
Condition: Cholestasis, Intrahepatic
Interventions: Drug: GSK2330672;   Drug: Placebo;   Drug: Ursodeoxycholic acid

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Indicates status has not been verified in more than two years