40 studies found for:    Open Studies | "Neurofibromatosis 1"
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Rank Status Study
21 Recruiting Ophthalmological Screening and Follow-up of Optic Pathway Gliomas in Children With Neurofibromatosis Type 1.
Condition: Neurofibromatosis Type 1
Intervention:
22 Recruiting Pegintron to Treat Plexiform Neurofibromas in Children and Young Adults
Conditions: Neurofibromatosis Type 1;   Plexiform Neurofibroma
Interventions: Drug: PEG-interferon alfa-2b;   Procedure: MRI
23 Unknown  Combination Chemotherapy in Treating Patients With Neurofibromatosis and Progressive Plexiform Neurofibromas
Conditions: Neurofibromatosis Type 1;   Precancerous Condition
Interventions: Drug: methotrexate;   Drug: vinblastine sulfate
24 Recruiting Study of RAD001 for Treatment of NF2-related Vestibular Schwannoma
Conditions: Neurofibromatosis Type 2;   Neuroma, Acoustic
Intervention: Drug: RAD001, everolimus
25 Recruiting Phase 2 Study of Bevacizumab in Children and Young Adults With NF 2 and Progressive Vestibular Schwannomas
Conditions: Neurofibromatosis Type 2;   Progressive Vestibular Schwannomas
Intervention: Drug: Bevacizumab
26 Recruiting Photodynamic Therapy (PDT) for Benign Dermal Neurofibromas (NF1)
Condition: Neurofibromatoses
Interventions: Drug: Levulan (5-aminolevulinic acid) uptake.;   Drug: Levulan (5-aminolevulinic acid) photodynamic therapy.
27 Recruiting Genetic Influences on Pediatric Brain Tumor Development in Neurofibromatosis Type 1
Conditions: Neurofibromatosis Type 1;   Pediatric Brain Tumor
Intervention:
28 Recruiting Concentration and Activity of Lapatinib in Vestibular Schwannomas
Conditions: Vestibular Schwannoma;   NF2;   Neurofibromatosis 2;   Acoustic Neuroma;   Auditory Tumor
Intervention: Drug: lapatinib
29 Recruiting Effect of Implant Position on Magnetic Resonance Image Distortion
Condition: Neurofibromatosis Type 2
Intervention: Device: MR imaging
30 Recruiting Exploring the Activity of RAD001 in Vestibular Schwannomas and Meningiomas
Conditions: Neurofibromatosis Type 2;   Vestibular Schwannomas;   Meningiomas
Intervention: Drug: RAD001 10mg p.o. daily
31 Recruiting Validating Pain Scales in Children and Young Adults
Conditions: Solid Tumor;   Leukemia;   Neurofibromatosis
Intervention:
32 Recruiting Selumetinib in Treating Young Patients With Recurrent or Refractory Low Grade Glioma
Conditions: Childhood Low-grade Cerebellar Astrocytoma;   Childhood Low-grade Cerebral Astrocytoma;   Childhood Mixed Glioma;   Childhood Pilocytic Astrocytoma;   Neurofibromatosis Type 1;   Recurrent Childhood Anaplastic Oligodendroglioma;   Recurrent Childhood Brain Stem Glioma;   Recurrent Childhood Cerebellar Astrocytoma;   Recurrent Childhood Cerebral Astrocytoma;   Recurrent Childhood Oligodendroglioma;   Recurrent Childhood Pilocytic Astrocytoma;   Recurrent Childhood Visual Pathway and Hypothalamic Glioma;   Recurrent Childhood Visual Pathway Glioma
Interventions: Drug: selumetinib;   Other: laboratory biomarker analysis;   Other: pharmacological study
33 Recruiting Study of Imatinib Mesylate in Neurofibromatosis Type I Patients Aged 2 to 21 With Plexiform Neurofibromas
Condition: Plexiform Neurofibromas
Intervention: Drug: Imatinib Mesylate
34 Recruiting Study of Everolimus With Bevacizumab to Treat Refractory Malignant Peripheral Nerve Sheath Tumors
Conditions: Malignant Peripheral Nerve Sheath Tumors;   MPNST;   Sarcoma
Interventions: Drug: everolimus;   Drug: bevacizumab
35 Recruiting Auditory Brainstem Implantation in Young Children
Conditions: Developmental Cochlear Nerve Deficiency;   Acquired Cochlear Nerve Deficiency;   Cochlear Aplasia;   Post-meningitis Cochlear Ossification;   Cochlear Malformation
Intervention: Device: Auditory Brainstem Implantation in Children
36 Recruiting The Use of a Distress Thermometer in a Pediatric Research Setting: An Exploratory Pilot Study
Conditions: Cancer;   HIV Infections
Intervention:
37 Recruiting Diagnosis of Pheochromocytoma
Condition: Pheochromocytoma
Intervention:
38 Unknown  First Clinical Study of Erbium - Yttrium Aluminium Garnet (YAG) Laser Vaporization of Cutaneous Neurofibromas
Condition: Cutaneous Neurofibromas
Intervention: Procedure: Erbium-YAG laser vaporization
39 Recruiting Proton Radiation Therapy for Spinal Tumors
Conditions: Nerve Sheath Tumors;   Neurofibroma
Interventions: Radiation: Proton Radiation for MPNST;   Radiation: Proton Radiation  for neurofibromas
40 Recruiting MEK162 for Patients With RAS/RAF/MEK Activated Tumors
Condition: Solid Tumor and Hematologic Malignancies
Intervention: Drug: MEK162

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