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32 studies found for:    Open Studies | "Neurofibromatosis 1"

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Rank Status Study
1 Recruiting AZD6244 Hydrogen Sulfate for Children With Nervous System Tumors
Conditions: Neurofibromatosis 1;   Neurofibromatosis Type 1;   NF 1;   Neurofibroma, Plexiform
Intervention: Drug: AZD6244 hyd sulfate
2 Recruiting Trial to Evaluate the Safety of Lovastatin in Individuals With Neurofibromatosis Type I (NF1)
Condition: Neurofibromatosis 1
Interventions: Drug: Lovastatin;   Drug: placebo pill
3 Recruiting Modifying Genes in Neurofibromatosis 1
Condition: Neurofibromatosis 1
Intervention: Other: No intervention
4 Unknown † Multi-Center Project: Spinal Abnormalities in Neurofibromatosis Type1 (NF1) Patients
Condition: Neurofibromatosis Type 1
Intervention:
5 Recruiting PET/MRI in CNS and Extra-CNS Tumors of Patients With Neurofibromatosis-1 (NF1)
Conditions: Neurofibromatosis-1;   Optic Glioma;   Plexiform Neurofibroma
Intervention:
6 Unknown † Neurofibromatosis Type 1 (NF1) and Tibial Dysplasia
Conditions: Neurofibromatosis Type 1;   Tibial Dysplasia
Intervention:
7 Recruiting Genetic Evaluation of NF1 and Scoliosis Patients
Conditions: Neurofibromatosis 1;   Scoliosis
Intervention: Genetic: Swab
8 Recruiting Neurobiology and Treatment of Reading Disability in NF-1
Conditions: Neurofibromatosis Type 1;   Reading Disabilities
Interventions: Behavioral: Tutoring Program I;   Behavioral: Tutoring Program II
9 Recruiting Efficacy and Safety of RAD001 in Treating Plexiform Neurofibromas (PN) Associated With Neurofibromatosis (NF1)
Condition: Plexiform Neurofibroma Associated With Neurofibromatosis Type 1
Intervention: Drug: Everolimus
10 Recruiting Natural History Study of Patients With Neurofibromatosis Type I
Conditions: Neurofibromatosis Type 1;   Malignant Peripheral Nerve Sheath Tumor;   Plexiform Neurofibroma;   Optic Glioma;   Neurofibroma
Intervention:
11 Unknown † Medical Treatment of "High-Risk" Neurofibromas
Condition: Neurofibromatosis 1
Interventions: Drug: Peg-Interferon alpha-2b;   Drug: Celecoxib (Celebrex);   Drug: Temozolomide (temodar);   Drug: Vincristine Sulfate (Oncovin)
12 Recruiting How Neurofibromatosis Type 1 (NF1) Affects Schoolwork and Self-Esteem
Condition: Neurofibromatosis Type 1
Intervention:
13 Recruiting Neurofibromatosis Type 1 Patient Registry
Condition: Neurofibromatosis Type 1
Intervention:
14 Recruiting Neuropsychological Impairment and Quality of Life in Neurofibromatosis Type 1
Condition: Neurofibromatosis Type 1
Intervention: Other: Neuropsychological examination and quality of life measures
15 Recruiting A Randomized Placebo-Controlled Study of Lovastatin in Children With Neurofibromatosis Type 1
Condition: Neurofibromatosis Type 1
Interventions: Drug: Lovastatin ™;   Device: placebo
16 Recruiting MicroRNAs in Patients With Neurofibromatosis Type 1
Conditions: Glioma;   Neurofibromatosis Type 1
Intervention:
17 Unknown † Fludeoxyglucose F 18 Positron Emission Tomography and Magnetic Resonance Perfusion Imaging in Patients With Neurofibromatosis 1 and Plexiform Neurofibroma
Conditions: Neurofibromatosis Type 1;   Precancerous Condition
Interventions: Procedure: magnetic resonance imaging;   Procedure: positron emission tomography;   Procedure: radionuclide imaging;   Radiation: fludeoxyglucose F 18;   Radiation: gadopentetate dimeglumine
18 Recruiting Whole Body Magnetic Resonance Imaging With Diffusion Weighted Imaging : Potential Role in Neurofibromatosis
Conditions: Whole Body Imaging;   Magnetic Resonance Imaging;   Neurofibromatosis 1;   Diffusion Magnetic Resonance Imaging;   Peripheral Nerve Sheath Tumors, Malignant
Intervention: Other: Additional imaging or surgery
19 Recruiting Pegintron to Treat Plexiform Neurofibromas in Children and Young Adults
Conditions: Neurofibromatosis Type 1;   Plexiform Neurofibroma
Intervention: Drug: PEG-interferon alfa-2b
20 Recruiting Study of Tasigna®/Nilotinib (AMN107) in Neurofibromatosis (NF1) Patients With Plexiform Neurofibromas
Conditions: Neurofibromatosis;   NF1;   Neurofibromas
Intervention: Drug: Tasigna
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† Indicates status has not been verified in more than two years