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125 studies found for:    Open Studies | "Neuroblastoma"

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Open Studies | "Neuroblastoma"
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Rank Status Study
1 Recruiting Vorinostat and Isotretinoin in Treating Patients With High-Risk Refractory or Recurrent Neuroblastoma
Conditions: Disseminated Neuroblastoma;   Localized Unresectable Neuroblastoma;   Recurrent Neuroblastoma;   Regional Neuroblastoma;   Stage 4S Neuroblastoma
Interventions: Drug: vorinostat;   Drug: isotretinoin;   Other: diagnostic laboratory biomarker analysis;   Other: pharmacological study
2 Recruiting Lenalidomide and Monoclonal Antibody With or Without Isotretinoin in Treating Younger Patients With Refractory or Recurrent Neuroblastoma
Conditions: Disseminated Neuroblastoma;   Localized Unresectable Neuroblastoma;   Recurrent Neuroblastoma;   Regional Neuroblastoma;   Stage 4S Neuroblastoma
Interventions: Drug: lenalidomide;   Biological: monoclonal antibody Ch14.18;   Drug: isotretinoin;   Other: pharmacological study;   Other: laboratory biomarker analysis
3 Recruiting Isotretinoin With or Without Monoclonal Antibody, Interleukin-2, and Sargramostim Following Stem Cell Transplantation in Treating Patients With Neuroblastoma
Conditions: Disseminated Neuroblastoma;   Localized Resectable Neuroblastoma;   Localized Unresectable Neuroblastoma;   Regional Neuroblastoma;   Stage 4S Neuroblastoma
Interventions: Drug: isotretinoin;   Biological: sargramostim;   Biological: monoclonal antibody Ch14.18;   Biological: aldesleukin;   Other: laboratory biomarker analysis;   Procedure: quality-of-life assessment;   Other: pharmacological study
4 Unknown † Genetic Biomarkers in Children With Neuroblastoma (Also Known as Neuroblastoma Epidemiology in North America [NENA])
Condition: Neuroblastoma
Interventions: Genetic: DNA analysis;   Genetic: cytogenetic analysis;   Genetic: polymerase chain reaction;   Genetic: polymorphism analysis;   Other: questionnaire administration;   Other: study of socioeconomic and demographic variables
5 Unknown † Study of Specimens From Young Patients With Neuroblastoma
Condition: Neuroblastoma
Interventions: Genetic: gene expression analysis;   Genetic: polymerase chain reaction;   Other: laboratory biomarker analysis
6 Unknown † Observation, Combination Chemotherapy, Radiation Therapy, and/or Autologous Stem Cell Transplant in Treating Young Patients With Neuroblastoma
Condition: Neuroblastoma
Interventions: Biological: filgrastim;   Drug: carboplatin;   Drug: cisplatin;   Drug: cyclophosphamide;   Drug: dacarbazine;   Drug: doxorubicin hydrochloride;   Drug: etoposide phosphate;   Drug: ifosfamide;   Drug: isotretinoin;   Drug: melphalan;   Drug: topotecan hydrochloride;   Drug: vincristine sulfate;   Drug: vindesine;   Procedure: autologous hematopoietic stem cell transplantation;   Procedure: conventional surgery;   Procedure: peripheral blood stem cell transplantation;   Radiation: iobenguane I 131;   Radiation: radiation therapy
7 Unknown † Surgery in Treating Patients With Neuroblastoma
Condition: Neuroblastoma
Intervention: Procedure: surgical procedure
8 Recruiting Biomarkers in Tumor Tissue Samples From Patients With Newly Diagnosed Neuroblastoma or Ganglioneuroblastoma
Condition: Neuroblastoma
Interventions: Genetic: fluorescence in situ hybridization;   Genetic: gene expression analysis;   Genetic: nucleic acid amplification;   Genetic: polymerase chain reaction;   Genetic: reverse transcriptase-polymerase chain reaction;   Other: cytology specimen collection procedure;   Other: flow cytometry;   Procedure: biopsy
9 Not yet recruiting Busulfan, Melphalan, and Stem Cell Transplant After Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma
Condition: Neuroblastoma
Interventions: Drug: Cisplatin;   Drug: Cyclophosphamide;   Drug: Doxorubicin;   Drug: Etoposide;   Drug: Topotecan;   Drug: Vincristine;   Radiation: Radiation Therapy;   Procedure: PBSC;   Procedure: ASCT: autologous stem cell transplant (busulfan, melphalan);   Drug: Busulfan;   Drug: Melphalan;   Drug: Mesna
10 Unknown † Iodobenzylguanidine Meta-I131 and Topotecan in Treating Young Patients With Refractory or Relapsed Metastatic Neuroblastoma
Condition: Neuroblastoma
Interventions: Drug: topotecan hydrochloride;   Procedure: autologous hematopoietic stem cell transplantation;   Radiation: iobenguane I 131;   Radiation: total-body irradiation
11 Unknown † Isotretinoin in Treating Young Patients With High-Risk Neuroblastoma
Condition: Neuroblastoma
Interventions: Drug: isotretinoin;   Genetic: DNA analysis;   Genetic: polymerase chain reaction;   Other: laboratory biomarker analysis;   Other: pharmacological study
12 Recruiting Combination Chemotherapy Followed by Stem Cell Transplant and Isotretinoin in Treating Young Patients With High-Risk Neuroblastoma
Condition: Neuroblastoma
Interventions: Biological: filgrastim;   Drug: carboplatin;   Drug: cisplatin;   Drug: cyclophosphamide;   Drug: dacarbazine;   Drug: doxorubicin hydrochloride;   Drug: etoposide phosphate;   Drug: ifosfamide;   Drug: isotretinoin;   Drug: melphalan;   Drug: topotecan hydrochloride;   Drug: vincristine sulfate;   Drug: vindesine;   Procedure: autologous hematopoietic stem cell transplantation;   Radiation: iobenguane I 131;   Radiation: radiation therapy
13 Unknown † Genetic Analysis Using Blood or Bone Marrow From Participants With Neuroblastoma or Noncancerous Conditions
Condition: Neuroblastoma
Interventions: Genetic: gene mapping;   Genetic: polymorphism analysis
14 Unknown † Combination Chemotherapy With or Without Filgrastim Before Surgery, High-Dose Chemotherapy, and Radiation Therapy Followed by Isotretinoin With or Without Monoclonal Antibody in Treating Patients With Neuroblastoma
Condition: Neuroblastoma
Interventions: Biological: filgrastim;   Biological: monoclonal antibody Ch14.18;   Drug: busulfan;   Drug: carboplatin;   Drug: cyclophosphamide;   Drug: etoposide;   Drug: isotretinoin;   Drug: melphalan;   Drug: vincristine sulfate;   Procedure: bone marrow ablation with stem cell support;   Procedure: conventional surgery;   Procedure: peripheral blood stem cell transplantation;   Radiation: radiation therapy
15 Unknown † Cyclophosphamide and Prednisone With or Without Immunoglobulin in Treating Abnormal Muscle Movement in Children With Neuroblastoma
Condition: Neuroblastoma
Interventions: Biological: therapeutic immune globulin;   Other: clinical observation
16 Recruiting N2007-03: Vorinostat and 131-I MIBG in Treating Patients With Resistant or Relapsed Neuroblastoma
Condition: Neuroblastoma
Interventions: Drug: Vorinostat;   Radiation: 131- I Metaiodobenzylguanidine;   Procedure: Peripheral Blood Stem Cell Infusion;   Drug: Filgrastim
17 Recruiting N99-02: Melphalan and Buthionine Sulfoximine Followed by Bone Marrow or Peripheral Stem Cell Transplantation in Treating Children With Resistant or Recurrent Neuroblastoma
Condition: Neuroblastoma
Interventions: Drug: buthionine sulfoximine;   Drug: melphalan;   Procedure: Peripheral blood stem cell infusion;   Other: Filgrastim
18 Recruiting Induction Therapy Including 131 I-MIBG and Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma Undergoing Stem Cell Transplant, Radiation Therapy, and Maintenance Therapy With Isotretinoin
Condition: Neuroblastoma
Interventions: Drug: busulfan;   Drug: cisplatin;   Drug: cyclophosphamide;   Drug: doxorubicin hydrochloride;   Drug: etoposide;   Drug: irinotecan hydrochloride;   Drug: isotretinoin;   Drug: melphalan;   Drug: topotecan hydrochloride;   Drug: vincristine sulfate;   Other: pharmacological study;   Other: questionnaire administration;   Procedure: autologous hematopoietic stem cell transplantation;   Procedure: peripheral blood stem cell transplantation;   Procedure: therapeutic conventional surgery;   Radiation: 3-dimensional conformal radiation therapy;   Radiation: external beam radiation therapy;   Radiation: intensity-modulated radiation therapy;   Radiation: iobenguane I 131
19 Unknown † Use of Rituximab in Opsoclonus-Myoclonus in Children With Neuroblastoma
Conditions: Neuroblastoma;   Opsoclonus-Myoclonus
Intervention: Drug: anti-CD20 (Rituximab)
20 Recruiting A Safety/Feasibility Trial of the Addition of the Humanized Anti-GD2 Antibody (hu14.18K322A) With and Without Natural Killer Cells to Chemotherapy in Children and Adolescents With Recurrent/Refractory Neuroblastoma
Condition: Neuroblastoma
Interventions: Biological: Humanized anti-GD2 antibody;   Drug: Chemotherapy;   Other: Cytokines;   Biological: Natural killer cells
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† Indicates status has not been verified in more than two years