13957 studies found for:    Open Studies | "Neoplasms"
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Rank Status Study
1 Recruiting Prospective Comprehensive Molecular Analysis of Endocrine Neoplasms
Conditions: Neuroendocrine Neoplasms;   Thyroid Neoplasms;   Parathyroid Neoplasms;   Adrenal Neoplasm;   Neuroblastoma
Intervention:
2 Recruiting A Study of CDX-1127 (Varlilumab) in Patients With Select Solid Tumor Types or Hematologic Cancers
Conditions: CD27 Expressing B-cell Malignancies, (for Example;   Chronic Lymphocytic Leukemia, Burkett's Lymphoma,;   Mantle Cell Lymphoma, Primary Lymphoma of the Central Nervous System,;   Marginal Zone B Cell Lymphoma);;   Any T-cell Malignancy;;   Solid Tumors (Metastatic Melanoma, Renal (Clear) Cell Carcinoma,;   Hormone-refractory Prostate Adenocarcinoma, Ovarian Cancer;   Colorectal Adenocarcinoma, Non-small Cell Lung Cancer)
Intervention: Drug: CDX-1127
3 Recruiting Early Detection of Pancreatic Cystic Neoplasms
Conditions: Pancreatic Cysts;   Intraductal Papillary Mucinous Neoplasm;   Pancreatic Mucinous-Cystic Neoplasm;   Cystic, Mucinous and/or Serous Neoplasm;   Solid Pseudopapillary Tumour of the Pancreas
Intervention:
4 Recruiting A Pivotal Bioequivalence Study of DOXIL/CAELYX (Doxorubicin HCL) in Patients With Advanced or Refractory Solid Malignancies Including Patients With Ovarian Cancer
Conditions: Neoplasms;   Neoplasms, Ovarian;   Neoplasms, Breast;   Advanced or Refractory Solid Malignancies
Interventions: Drug: DOXIL/CAELYX (doxorubicin) Treatment Sequence AB;   Drug: DOXIL/CAELYX (doxorubicin) Treatment Sequence BA
5 Recruiting To Find a Safe Dose and Show Early Clinical Activity of Weekly Nab-paclitaxel in Pediatric Patients With Recurrent/ Refractory Solid Tumors
Conditions: Neuroblastoma;;   Rhabdomyosarcoma;;   Ewing's Sarcoma;;   Ewing's Tumor;;   Sarcoma, Ewing's;;   Sarcomas, Epitheliod;;   Sarcoma, Soft Tissue;;   Sarcoma, Spindle Cell;;   Melanoma;;   Malignant Melanoma;;   Clinical Oncology;;   Oncology, Medical;;   Pediatrics, Osteosarcoma;;   Osteogenic Sarcoma;;   Osteosarcoma Tumor;;   Sarcoma, Osteogenic;;   Tumors;;   Cancer;;   Neoplasia;;   Neoplasm;;   Histiocytoma;;   Fibrosarcoma;;   Dermatofibrosarcoma
Intervention: Drug: nab-paclitaxel
6 Recruiting Study of Safety and Efficacy of BYL719 With Everolimus or BYL719 With Everolimus and Exemestane in Advanced Breast Cancer Patients, Renal Cell Cancer and Pancreatic Tumors
Conditions: Neoplasms,;   Breast Neoplasms,;   Kidney Neoplasms,;   Pancreatic Neuroendocine Neoplasms
Interventions: Drug: BYL719;   Drug: Everolimus;   Drug: Exemestane
7 Recruiting A Study of Oral LGK974 in Patients With Malignancies Dependent on Wnt Ligands
Conditions: Melanoma;   Breast Neoplasms;   Lobular Carcinoma;   Triple-negative Breast Cancer;   Pancreatic Adenocarcinoma;   Colorectal Cancer;   Head and Neck Cancer;   Other Tumor Types With Documented Genetic Alterations Upstream in the Wnt Signaling Pathway
Intervention: Drug: LGK974
8 Recruiting An Open-Label, Multicenter, Phase 1/2 Study of Poly(ADP-Ribose) Polymerase (PARP) Inhibitor E7449 as Single Agent in Subjects With Advanced Solid Tumors or With B-cell Malignancies and in Combination With Temozolomide (TMZ) or With Carboplatin and Paclitaxel in Subjects With Advanced Solid Tumors
Conditions: Malignant Solid Tumour;   Ovarian Cancer;   Triple Negative Breast Cancer;   Advanced Melanoma;   B-cell Malignancy, Low-grade
Interventions: Drug: E7449 alone;   Drug: E7449 plus TMZ;   Drug: E7449 plus carboplatin and paclitaxel
9 Not yet recruiting CC-486 (Oral Azacitidine) Bioequivalence Study in Patients With Solid Tumor or Hematologic Malignancies
Conditions: Hematological Neoplasms;   Non-Hodgkin's Lymphoma;   Hodgkin's Lymphoma;   Lymphoma;   Multiple Myeloma;   Acute Myeloid Leukemia;   Leukemia;   Myelodysplastic Syndromes;   Neoplasms;   Melanoma;   Breast Cancer;   Metastatic Breast Cancer;   Non-Small Cell Lung Cancer;   Small Cell Lung Cancer;   Renal Cell Carcinoma;   Glioblastoma Multiforme;   Osteosarcoma;   Sarcoma;   Thyroid Cancer;   Genitourinary
Interventions: Drug: CC-486;   Drug: Vidaza
10 Recruiting Topical Interferon Alfa 2b and Mitomycin C in Conjunctival-Corneal Intraepithelial Neoplasia
Conditions: Conjunctival Intraepithelial Neoplasia;   Corneal Intraepithelial Neoplasia
Interventions: Drug: Mitomycin C;   Drug: Interferon Alfa-2b
11 Recruiting The Impact of the "WOMAN-PRO II Program" on Patients With Vulvar Neoplasia to Minimize Post-surgical Symptom Prevalence
Conditions: Vulvar Cancer;   Vulvar Intraepithelial Neoplasia
Interventions: Behavioral: standardized care (Intervention I);   Behavioral: Standardized care + WOMAN-PRO II program (Intervention II)
12 Not yet recruiting Dose-finding, Safety Study of Plasmid DNA Therapeutic Vaccine to Treat Cervical Intraepithelial Neoplasia
Condition: Cervical Intraepithelial Neoplasia
Intervention: Biological: GX-188E
13 Recruiting Investigate the Safety and Tolerability of AZD6244 Monotherapy or + Docetaxel in Japanese Patients With Advanced Solid Malignancies or Non-Small Cell Lung Cancer
Conditions: Neoplasms,;   Metastatic Cancer,;   Non-Small Cell Lung Cancer;   Advanced Solid Malignancies
Interventions: Drug: AZD6244;   Drug: Docetaxel
14 Unknown  Radiolabeled Octreotide in Treating Children With Advanced or Refractory Solid Tumors
Conditions: Brain and Central Nervous System Tumors;   Gastrointestinal Carcinoid Tumor;   Islet Cell Tumor;   Neuroblastoma;   Pheochromocytoma;   Sarcoma;   Unspecified Childhood Solid Tumor, Protocol Specific
Intervention: Radiation: yttrium Y 90-edotreotide
15 Recruiting Oral Bicarbonate as Adjuvant for Pain Reduction in Patients With Tumor Related Pain
Conditions: Tumor;   Cancer;   Pain;   Malignant Solid Tumor;   Unresectable Malignant Neoplasm;   Hematologic Malignancy;   Multiple Myeloma;   Lymphoma;   Neoplasm Metastasis
Intervention: Drug: Sodium Bicarbonate
16 Recruiting Endoscopic Ultrasound (EUS) Guided Ethanol With Paclitaxel Ablation for Pancreatic Mucinous Cystic Neoplasm
Conditions: Mucinous Cystic Tumor With Moderate Dysplasia;   Mucinous Cystadenoma of Pancreas;   Mucinous Cystadenocarcinoma of Pancreas;   Benign Neoplasm of Pancreas
Intervention: Drug: Ethanol and Paclitaxel Injection
17 Recruiting Topical Imiquimod Versus Conization to Treat Cervical Intraepithelial Neoplasia
Condition: Cervical Intraepithelial Neoplasia
Interventions: Drug: Topical Imiquimod;   Procedure: Conization
18 Recruiting Fusion Guided Thermal Ablation Combined With External Beam Radiation for Hepatic Neoplasms
Conditions: Liver Neoplasms;   Hepatic Cancer;   Liver Cancer
Interventions: Procedure: Thermal Ablation;   Procedure: Standard External Beam Radiation Therapy
19 Recruiting A Phase 1 Study of CC-486 as a Single Agent and in Combination With Carboplatin or ABI-007 in Subjects With Relapsed or Refractory Solid Tumors
Conditions: Urinary Bladder Neoplasms;   Carcinoma, Transitional Cell;   Ovarian Neoplasms;   Fallopian Tube Neoplasms;   Peritoneal Neoplasms;   Carcinoma, Non-Small-Cell Lung;   Carcinoma, Pancreatic Ductal;   Tumor Virus Infections
Interventions: Drug: CC-486 plus Carboplatin;   Drug: CC-486 plus ABI-007;   Drug: CC-486
20 Recruiting Intrathecal Rituximab in Lymphoid Malignancies Involving Central Nervous System
Conditions: Leukemia;   Lymphoid Malignancies;   Metastatic Malignant Neoplasm to the Leptomeninges
Intervention: Drug: Intrathecal Rituximab

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