350 studies found for:    Open Studies | "Myeloproliferative Disorders"
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21 Recruiting Correlative Biomarker Study in Patients With Myeloproliferative Disorders
Conditions: Myeloproliferative Disease;   Myelofibrosis;   Idiopathic Myelofibrosis;   Essential Thrombocythemia;   Polycythemia Vera
Intervention:
22 Unknown  Study of STI571 in the Treatment of Patients With Idiopathic Hypereosinophilic Syndrome (HES) and Eosinophilic Leukemias
Conditions: Hypereosinophilic Syndrome;   Chronic Eosinophilic Leukemia (CEL);   Myeloproliferative Disorders
Intervention: Drug: STI571
23 Recruiting Study of LY2784544 Testing Alternative Dosing in Participants With Myeloproliferative Neoplasms
Conditions: Myeloproliferative Neoplasms of;   Polycythemia Vera;   Essential Thrombocythemia;   Myelofibrosis
Intervention: Drug: LY2784544
24 Recruiting Screening for Asymptomatic Portal Vein Thrombosis and Portal Hypertension in Patients With Philadelphia Negative Myeloproliferative Neoplasms
Conditions: Myeloproliferative Neoplasms (MPN);   Polycythemia Vera (PV);   Essential Thrombocythemia (ET);   Myelofibrosis (MF)
Intervention: Procedure: Upper gastrointestinal endoscopy and Doppler ultrasound
25 Recruiting Study of Molecular and Genetic Abnormalities in Patients With Myeloid Neoplasms
Conditions: Acute Myeloid Leukemia;   Myeloproliferative Neoplasms;   Myelodysplastic Syndromes;   Myeloproliferative/Myelodysplastic Neoplasm
Interventions: Drug: Induction Chemotherapy;   Drug: Consolidation Chemotherapy;   Drug: Autologous Stem Cell Transplantation;   Drug: Allogeneic Stem Cell Transplantation;   Drug: Low Dose Cytarabine;   Drug: Decitabine
26 Recruiting Study of Combination Ruxolitinib and Decitabine Treatment for Accelerated Phase MPN or Post-MPN AML
Condition: Myeloproliferative Neoplasms
Interventions: Drug: Ruxolitinib;   Drug: Decitabine
27 Recruiting A Study of Anagrelide Controlled Release (GALE-401) in Patients With High Platelet Counts Due to Bone Marrow Disorders
Conditions: Thrombocytosis;   Myeloproliferative Neoplasms
Intervention: Drug: Anagrelide CR
28 Recruiting Long-term Study Evaluating the Effect of Givinostat in Patients With Chronic Myeloproliferative Neoplasms
Condition: Chronic Myeloproliferative Neoplasms (cMPN)
Intervention: Drug: Givinostat
29 Recruiting Comparison Between Cyclophosphamide and Combination of Methotrexate + Calcineurin Inhibitor for GVHD Prophylaxis
Conditions: Acute Myelogenous Leukemia;   Acute Lymphoid Leukemia;   Myeloproliferative Disease;   Myelodysplastic Syndrome;   Chronic Myeloid Leukemia;   Chronic Myelomonocytic Leukemia
Interventions: Drug: ARM A Cyclophosphamide;   Drug: ARM B Calcineurin inhibitor and methotrexate
30 Recruiting PRO#1278: Fludarabine and Busulfan vs. Fludarabine, Busulfan and Total Body Irradiation
Conditions: Myeloid Malignancies;   Acute Myelogenous Leukemia;   Chronic Myelogenous Leukemia;   Myeloproliferative Disorders;   Myelodysplastic Syndrome
Interventions: Drug: Fludarabine and Busulfan plus/minus Total Body Irradiation (low dose);   Drug: Fludarabine and Busulfan + Low Dose Total Body Irradiation (TBI)
31 Recruiting A First-in-Human Phase 1 and Expanded Cohort Study of EPZ-5676 in Advanced Hematologic Malignancies, Including Acute Leukemia With Rearrangement of the MLL Gene
Conditions: Acute Myeloid Leukemia;   Acute Lymphoblastic Leukemia;   Myelodysplastic Syndrome;   Myeloproliferative Disorders;   Chronic Myeloid Leukemia
Intervention: Drug: EPZ-5676
32 Recruiting A Phase Ib/II Dose-finding Study to Assess the Safety and Efficacy of LDE225 + INC424 in Patients With MF
Conditions: Primary Myelofibrosis;   Thrombocythemia, Essential;   Thrombocytosis;   Myeloproliferative Disorders;   Bone Marrow Diseases;   Hematologic Diseases;   Blood Coagulation Disorders;   Blood Platelet Disorders;   Hemorrhagic Disorders
Interventions: Drug: LDE225;   Drug: INC424
33 Recruiting Preservation of Ovarian Function After Hematopoietic Cell Transplant
Conditions: Multiple Myeloma;   Non-Hodgkin Lymphoma;   Hodgkin Disease;   Acute Myeloid Leukemia;   Myeloproliferative Disorders
Interventions: Drug: Leuprolide;   Biological: hematopoietic cell transplant;   Biological: reduced intensity allogeneic HCT
34 Recruiting Non-Myeloablative Conditioning for Unrelated Donor Umbilical Cord Blood Transplant
Conditions: Myeloproliferative Disorders;   Leukemia;   Lymphoma;   Myelodysplastic Syndromes
Interventions: Biological: anti-thymocyte globulin;   Drug: cyclophosphamide;   Drug: Fludarabine;   Drug: mycophenolate mofetil;   Procedure: umbilical cord blood transplantation;   Radiation: total body irradiation;   Drug: Sirolimus
35 Recruiting MSC and HSC Coinfusion in Mismatched Minitransplants
Conditions: Leukemia, Myeloid, Acute;   Leukemia, Lymphoblastic, Acute;   Leukemia, Myelocytic, Chronic;   Myeloproliferative Disorders;   Myelodysplastic Syndromes;   Multiple Myeloma;   Leukemia, Lymphocytic, Chronic;   Hodgkin's Disease;   Lymphoma, Non-Hodgkin
Interventions: Biological: Mesenchymal stem cells;   Other: Isotonic solution
36 Recruiting Donor Stem Cell Transplant With No or Low-Intensity Chemotherapy Using Sirolimus and Treated Immune Cells to Treat Blood and Lymph Cancers
Conditions: Hematologic Neoplasms;   Neural Tube Defects;   Myeloproliferative Disorders
Interventions: Biological: therapeutic allogeneic lymphocytes;   Drug: Sirolimus
37 Recruiting Decitabine and Cytarabine in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia, High Risk Myelodysplastic Syndrome, or Myeloproliferative Neoplasm
Conditions: Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities;   Adult Acute Myeloid Leukemia With Del(5q);   Adult Acute Myeloid Leukemia With Inv(16)(p13;q22);   Adult Acute Myeloid Leukemia With t(15;17)(q22;q12);   Adult Acute Myeloid Leukemia With t(16;16)(p13;q22);   Adult Acute Myeloid Leukemia With t(8;21)(q22;q22);   Chronic Myelomonocytic Leukemia;   de Novo Myelodysplastic Syndromes;   Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable;   Previously Treated Myelodysplastic Syndromes;   Untreated Adult Acute Myeloid Leukemia
Interventions: Drug: decitabine;   Drug: cytarabine
38 Recruiting Specialized Blood Cell Transplants for Cancers of the Blood and Bone Marrow
Conditions: Hematologic Disease;   Lymphoma;   Multiple Myeloma;   Myelodysplastic Syndrome;   Myeloproliferative Disorder
Intervention: Procedure: Stem cell transplantation
39 Unknown  Azacytidine and Bortezomib in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndromes
Conditions: Leukemia;   Myelodysplastic Syndromes;   Myelodysplastic/Myeloproliferative Neoplasms
Interventions: Drug: azacitidine;   Drug: bortezomib
40 Unknown  Early Diagnosis of Aspergillosis in Patients at High Risk of Fungal Infection Caused by Treatment for Hematologic Cancer or Other Disease
Conditions: Graft Versus Host Disease;   Infection;   Leukemia;   Myelodysplastic Syndromes;   Myelodysplastic/Myeloproliferative Neoplasms
Interventions: Genetic: polymerase chain reaction;   Other: bronchoalveolar lavage;   Other: immunoenzyme technique;   Other: laboratory biomarker analysis;   Procedure: bronchoscopy;   Procedure: management of therapy complications

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