1275 studies found for:    Open Studies | "Leukemia"
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Rank Status Study
21 Recruiting Phase II MOR00208 in Combination With Lenalidomide for Patients With Relapsed or Refractory CLL, SLL or PLL or Older Patients With Untreated CLL, SLL or PLL
Conditions: Contiguous Stage II Small Lymphocytic Lymphoma;   Noncontiguous Stage II Small Lymphocytic Lymphoma;   Prolymphocytic Leukemia;   Recurrent Small Lymphocytic Lymphoma;   Refractory Chronic Lymphocytic Leukemia;   Stage I Chronic Lymphocytic Leukemia;   Stage I Small Lymphocytic Lymphoma;   Stage II Chronic Lymphocytic Leukemia;   Stage III Chronic Lymphocytic Leukemia;   Stage III Small Lymphocytic Lymphoma;   Stage IV Chronic Lymphocytic Leukemia;   Stage IV Small Lymphocytic Lymphoma
Interventions: Biological: MOR00208;   Drug: lenalidomide;   Other: Correlative Studies
22 Recruiting Phase I Combination of Midostaurin, Bortezomib, and Chemo in Relapsed/Refractory Acute Myeloid Leukemia
Conditions: Acute Myeloid Leukemia;   Acute Myeloid Leukemia With Multilineage Dysplasia Following;   Myelodysplastic Syndrome;   Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities;   Adult Acute Myeloid Leukemia With Del(5q);   Adult Acute Myeloid Leukemia With Inv(16)(p13;q22);   Adult Acute Myeloid Leukemia With t(15;17)(q22;q12);   Adult Acute Myeloid Leukemia With t(16;16)(p13;q22);   Adult Acute Myeloid Leukemia With t(8;21)(q22;q22);   Recurrent Adult Acute Myeloid Leukemia;   Secondary Acute Myeloid Leukemia
Interventions: Drug: midostaurin;   Drug: Bortezomib;   Drug: mitoxantrone hydrochloride;   Drug: etoposide;   Drug: cytarabine
23 Recruiting AR-42 and Decitabine in Treating Patients With Acute Myeloid Leukemia
Conditions: Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities;   Adult Acute Myeloid Leukemia With Del(5q);   Adult Acute Myeloid Leukemia With Inv(16)(p13;q22);   Adult Acute Myeloid Leukemia With t(15;17)(q22;q12);   Adult Acute Myeloid Leukemia With t(16;16)(p13;q22);   Adult Acute Myeloid Leukemia With t(8;21)(q22;q22);   Recurrent Adult Acute Myeloid Leukemia;   Recurrent Childhood Acute Myeloid Leukemia;   Secondary Acute Myeloid Leukemia;   Untreated Adult Acute Myeloid Leukemia
Interventions: Drug: HDAC inhibitor AR-42;   Drug: decitabine;   Other: laboratory biomarker analysis;   Other: pharmacological study
24 Unknown  Fludarabine and Darbepoetin Alfa in Treating Older Patients With Chronic Lymphocytic Leukemia
Conditions: Anemia;   Leukemia
Interventions: Biological: darbepoetin alfa;   Drug: fludarabine phosphate
25 Recruiting Red Cell Transfusion Goals in Patients With Acute Leukemias
Conditions: Acute Lymphoblastic Leukemia;   Acute Lymphocytic Leukemia (ALL);   Acute Myelogenous Leukemia (AML);   Acute Promyelocytic Leukemia (APL)
Interventions: Procedure: Restrictive Transfusion threshold;   Procedure: Standard transfusion threshold
26 Not yet recruiting Phase I/II Study of Nilotinib/Ruxolitinb Therapy for TKI Resistant Ph-Leukemia
Conditions: Chronic Phase Chronic Myeloid Leukemia;   Accelerated Phase Chronic Myeloid Leukemia;   Blastic Phase Chronic Myeloid Leukemia;   Philadelphia Positive Acute Lymphoblastic Leukemia;   Resistant to Tyrosine Kinase Inhibitor Therapy
Interventions: Drug: Nilotinib;   Drug: Ruxolitinib
27 Unknown  A Study Using Two Oral Chemotherapy Agents for Chronic Lymphocytic Leukemia
Conditions: Chronic Lymphocytic Leukemia;   Leukemia
Intervention: Drug: dasatinib and lenalidomide
28 Unknown  Bendamustine Hydrochloride Injection for Previously Untreated Chronic Lymphocytic Leukemia
Conditions: Chronic Lymphocytic Leukemia;   Leukemia;   Neoplasms
Interventions: Drug: Bendamustine Hydrochloride Injection;   Drug: Chlorambucil
29 Recruiting Acute Promyelocytic Leukemia 2006 (APL)
Condition: Leukemia, Promyelocytic, Acute
Interventions: Procedure: Arsenic trioxide;   Procedure: ATRA
30 Recruiting Decitabine and Selinexor in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia
Conditions: Acute Myeloid Leukemia;   Secondary Acute Myeloid Leukemia;   Untreated Adult Acute Myeloid Leukemia
Interventions: Drug: decitabine;   Drug: selinexor;   Other: pharmacological study;   Other: laboratory biomarker analysis
31 Recruiting Rituximab and Alemtuzumab in Treating Older Patients With Progressive Chronic Lymphocytic Leukemia
Condition: Leukemia
Interventions: Biological: alemtuzumab;   Biological: rituximab
32 Unknown  Study of NRX 195183 Therapy for Patients With Relapsed or Refractory Acute Promyelocytic Leukemia
Condition: Acute Promyelocytic Leukemia
Intervention: Drug: NRX 195183 Soft Gelatin Capsule
33 Recruiting CD19-specific T-cell for Chronic Lymphocytic Leukemia (CLL)
Conditions: Advanced Cancers;   Leukemia
Interventions: Procedure: Leukapheresis;   Drug: Fludarabine;   Drug: Cyclophosphamide;   Procedure: T-cell Infusion
34 Unknown  Alemtuzumab in Treating Patients With B-Cell Chronic Lymphocytic Leukemia
Conditions: Infection;   Leukemia
Interventions: Biological: alemtuzumab;   Genetic: polymerase chain reaction;   Other: flow cytometry;   Other: laboratory biomarker analysis;   Other: pharmacological study
35 Recruiting Allogeneic Stem Cell Transplant for Chronic Lymphocytic Leukemia (CLL)
Condition: Leukemia
Interventions: Drug: Busulfan;   Drug: Clofarabine;   Drug: Gemcitabine;   Drug: Thymoglobulin;   Procedure: Allogeneic Stem Cell Transplantation;   Drug: Filgrastim;   Drug: Tacrolimus;   Drug: Methotrexate
36 Not yet recruiting Autologous ROR1R-CAR-T Cells for Chronic Lymphocytic Leukemia (CLL)
Condition: Leukemia
Interventions: Procedure: ROR1R-CAR-T Cell Infusion;   Drug: Fludarabine;   Drug: Cyclophosphamide;   Drug: Rituximab;   Drug: Bendamustine
37 Recruiting A First-in-Human Phase 1 and Expanded Cohort Study of EPZ-5676 in Advanced Hematologic Malignancies, Including Acute Leukemia With Rearrangement of the MLL Gene
Conditions: Acute Myeloid Leukemia;   Acute Lymphoblastic Leukemia;   Myelodysplastic Syndrome;   Myeloproliferative Disorders;   Chronic Myeloid Leukemia
Intervention: Drug: EPZ-5676
38 Recruiting Donor Stem Cell Transplant in Treating Patients With Previously Treated Lymphoma, Multiple Myeloma, or Chronic Lymphocytic Leukemia
Conditions: Leukemia;   Lymphoma;   Multiple Myeloma and Plasma Cell Neoplasm
Interventions: Drug: busulfan;   Drug: cyclophosphamide;   Biological: Stem cell infusion;   Radiation: Total body irradiation
39 Recruiting Phase II Study of Ofatumumab in Elderly Patients With Chronic Lymphocytic Leukemia (CLL)
Conditions: Advanced Cancers;   Leukemia
Intervention: Drug: Ofatumumab
40 Unknown  Combination Chemotherapy and Rituximab in Treating Patients With Chronic Lymphocytic Leukemia That Did Not Respond to Fludarabine (Closed to Entry as of 10/2006), Chronic Lymphocytic Leukemia With Autoimmune Hemolytic Anemia, or Richter Transformation
Condition: Leukemia
Interventions: Biological: rituximab;   Drug: cyclophosphamide;   Drug: doxorubicin hydrochloride;   Drug: prednisone;   Drug: vincristine sulfate

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Indicates status has not been verified in more than two years