4713 studies found for:    Open Studies | "Immune System Diseases"
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Rank Status Study
21 Not yet recruiting Effect of Midazolam on Inflammatory Response and Organ Function in Mechanically Ventilated Sepsis Patients With Different Immune Status
Conditions: Inflammatory Disorder of Immune System;   Sepsis
Interventions: Other: blood sample collection;   Drug: Midazolam;   Drug: Morphine;   Procedure: Sedation interruption
22 Recruiting Investigation of Immune Disorders and Deficiencies
Conditions: Primary Immune Deficiencies;   Autoimmune Diseases;   Inflammatory Diseases;   Common Variable Immune Deficiencies;   Hypogammaglobulinemia
Intervention:
23 Unknown  Vitamin D Deficiency Causes Immune Dysfunction and Enables or Perpetuates the Development of Rheumatoid Arthritis
Conditions: Arthritis, Rheumatoid;   Vitamin D Deficiency
Interventions: Drug: Placebo in arm A and Vitamin D in arm B;   Drug: vitamin D 3 for arm A ,and matching placebo for arm B
24 Recruiting Immune Disorder HSCT Protocol
Conditions: Immune Deficiency Disorders:;   Severe Combined Immunodeficiency;   Chronic Granulomatous Disease;   X-linked Agammaglobulinemia;   Wiskott-Aldrich Syndrome;   Hyper-IgM;   DiGeorge Syndrome;   Chediak-Higashi Syndrome;   Common Variable Immune Deficiency;   Immune Dysregulatory Disorder:;   Hemophagocytic Lymphohistiocytosis;   IPEX;   Autoimmune Lymphoproliferative Syndrome;   X-linked Lymphoproliferative Syndrome
Intervention: Drug: Transplant preparative regimen of alemtuzumab, fludarabine, thiotepa, and melphalan
25 Recruiting Participation in a Research Registry for Immune Disorders
Conditions: ADA-SCID;   Adenosine Deaminase Deficiency;   Wiskott- Aldrich Syndrome;   Primary Immunodeficiencies;   Severe Combined Immune Deficiency
Intervention:
26 Recruiting Oral Bacteria and Immune System Problems Involved in Gum Disease (Periodontitis)
Conditions: Immunosuppression;   Periodontal Disease;   Healthy Subjects;   Healthy Volunteer
Intervention:
27 Recruiting Assessment of Immunoglobulins (IgG) in a Long-term Non-interventional Study
Conditions: Primary Immunodeficiency (PID);   Secondary Immunodeficiency (SID);   Neurological Autoimmune Disease
Intervention: Other: Immunoglobulin G (IgG)
28 Recruiting Severe Asthma Research Program - University of Virginia
Condition: Asthma
Intervention:
29 Recruiting A Study of Brentuximab Vedotin in Patients With Relapsed or Refractory Hodgkin Lymphoma
Condition: Hodgkin Lymphoma
Intervention: Drug: Brentuximab vedotin
30 Recruiting Early cART and cART in Combination With Autologous HIV-1 Specific Cytotoxic T Lymphocyte (CTL) Infusion in The Treatment of Acute HIV-1 Infected Adults
Condition: Acute HIV Infection
Interventions: Drug: cART(TDF/AZT+3TC+LPV/r);   Procedure: CTL infusion
31 Recruiting International Guillain-Barré Syndrome Outcome Study
Conditions: Guillain-Barré Syndrome;   Miller Fisher Syndrome
Intervention:
32 Recruiting Mesenchymal Stem Cells as a Treatment for Oral Complications of Graft-versus-host Disease
Condition: Graft -Versus-host-disease
Intervention: Biological: Mesenchymal stromal cells
33 Recruiting A Study to Evaluate the Effect of Belimumab on Vaccine Responses in Subjects With Systemic Lupus Erythematosus (SLE)
Condition: Systemic Lupus Erythematosus
Interventions: Biological: Belimumab plus Early Vaccination;   Biological: Belimumab plus Late Vaccination
34 Recruiting Safety and Efficacy Study of T-Guard to Treat Steroid-resistant Acute GVHD
Condition: Graft vs Host Disease
Intervention: Biological: T-Guard
35 Recruiting Prognostic Potential Cell Surface Marker and Pim-kinase in Patients With Hematologic Malignancies or Solid Tumors
Conditions: Solid Tumor;   Ovarian Cancer;   Non-small Cell Lung Cancer;   Chronic Lymphocytic Leukemia;   Burkitt's Lymphoma
Intervention:
36 Recruiting ACP-196, a Btk Inhibitor, for Treatment of Novo Activated B-cell (ABC) Subtype of Diffuse Large B-Cell Lymphoma
Condition: Activated B-cell Diffuse Large B-Cell Lymphoma (ABC DLBCL)
Intervention: Drug: ACP-196
37 Recruiting Safety and Effectiveness of Belimumab in Systemic Lupus Erythematosus Registry
Condition: Systemic Lupus Erythematosus
Interventions: Biological: BENLYSTA;   Other: SLE treatment
38 Not yet recruiting Gene Therapy for B-Cell Non-Hodgkin Lymphoma Using CD19 CAR Gene Transduced T Lymphocytes
Condition: Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma
Interventions: Drug: Cyclophosphamide or Bendamustine;   Genetic: Dose Level -1;   Genetic: Dose Level 1;   Genetic: Dose Level 2;   Genetic: Dose Level 3
39 Available Expanded Access Protocol (EAP) Using the CliniMACS® Device for Pediatric Haplocompatible Donor Stem Cell Transplant
Conditions: Acute Lymphoblastic Leukemia;   Acute Myeloid Leukemia;   Chronic Myeloid Leukemia;   Myelodysplastic Syndrome;   Lymphomas;   Bone Marrow Failure;   Hemoglobinopathy;   Immune Deficiency;   Osteopetrosis;   Cytopenias;   White Blood Cell Abnormalities;   Red Blood Cell Abnormalities
Intervention: Biological: CD34+ enriched, T Cell Depleted donor stem cell product
40 Recruiting Comprehensive Multimodal Analysis of Neuroimmunological Diseases of the Central Nervous System
Conditions: Central Nervous System Disease;   Multiple Sclerosis
Intervention:

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Indicates status has not been verified in more than two years