5005 studies found for:    Open Studies | "Immune System Diseases"
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Rank Status Study
21 Recruiting Investigation of Immune Disorders and Deficiencies
Conditions: Primary Immune Deficiencies;   Autoimmune Diseases;   Inflammatory Diseases;   Common Variable Immune Deficiencies;   Hypogammaglobulinemia
Intervention:
22 Unknown  Vitamin D Deficiency Causes Immune Dysfunction and Enables or Perpetuates the Development of Rheumatoid Arthritis
Conditions: Arthritis, Rheumatoid;   Vitamin D Deficiency
Interventions: Drug: Placebo in arm A and Vitamin D in arm B;   Drug: vitamin D 3 for arm A ,and matching placebo for arm B
23 Recruiting Immune Disorder HSCT Protocol
Conditions: Immune Deficiency Disorders:;   Severe Combined Immunodeficiency;   Chronic Granulomatous Disease;   X-linked Agammaglobulinemia;   Wiskott-Aldrich Syndrome;   Hyper-IgM;   DiGeorge Syndrome;   Chediak-Higashi Syndrome;   Common Variable Immune Deficiency;   Immune Dysregulatory Disorder:;   Hemophagocytic Lymphohistiocytosis;   IPEX;   Autoimmune Lymphoproliferative Syndrome;   X-linked Lymphoproliferative Syndrome
Intervention: Drug: Transplant preparative regimen of alemtuzumab, fludarabine, thiotepa, and melphalan
24 Recruiting Participation in a Research Registry for Immune Disorders
Conditions: ADA-SCID;   Adenosine Deaminase Deficiency;   Wiskott- Aldrich Syndrome;   Primary Immunodeficiencies;   Severe Combined Immune Deficiency
Intervention:
25 Recruiting Assessment of Immunoglobulins (IgG) in a Long-term Non-interventional Study
Conditions: Primary Immunodeficiency (PID);   Secondary Immunodeficiency (SID);   Neurological Autoimmune Disease
Intervention: Other: Immunoglobulin G (IgG)
26 Recruiting Safety and Efficacy Study of T-Guard to Treat Steroid-resistant Acute GVHD
Condition: Graft vs Host Disease
Intervention: Biological: T-Guard
27 Available Expanded Access Protocol (EAP) Using the CliniMACS® Device for Pediatric Haplocompatible Donor Stem Cell Transplant
Conditions: Acute Lymphoblastic Leukemia;   Acute Myeloid Leukemia;   Chronic Myeloid Leukemia;   Myelodysplastic Syndrome;   Lymphomas;   Bone Marrow Failure;   Hemoglobinopathy;   Immune Deficiency;   Osteopetrosis;   Cytopenias;   White Blood Cell Abnormalities;   Red Blood Cell Abnormalities
Intervention: Biological: CD34+ enriched, T Cell Depleted donor stem cell product
28 Recruiting Mesenchymal Stem Cells as a Treatment for Oral Complications of Graft-versus-host Disease
Condition: Graft -Versus-host-disease
Intervention: Biological: Mesenchymal stromal cells
29 Not yet recruiting ACP-196, a Btk Inhibitor, for Treatment of Novo Activated B-cell (ABC) Subtype of Diffuse Large B-Cell Lymphoma
Condition: Activated B-cell Diffuse Large B-Cell Lymphoma (ABC DLBCL)
Intervention: Drug: ACP-196
30 Recruiting A Phase 1/2 Study of Ponatinib in Japanese Patients With Chronic Myeloid Leukemia (CML) and Ph+ Acute Lymphoblastic Leukemia (ALL)
Conditions: Chronic Myeloid Leukemia (CML);   Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph+ ALL)
Interventions: Drug: ponatinib - Phase 1;   Drug: ponatinib - Phase 2
31 Recruiting A Study of Brentuximab Vedotin in Patients With Relapsed or Refractory Hodgkin Lymphoma
Condition: Hodgkin Lymphoma
Intervention: Drug: Brentuximab vedotin
32 Recruiting A Study to Evaluate Safety and Tolerability of IV or SC Dose of MEDI-545 in Patients With Systemic Lupus Erythematosus
Condition: Systemic Lupus Erythematosus
Interventions: Drug: MEDI-545;   Drug: MEDI-545 600
33 Recruiting Efficacy and Safety of AIN457 (Secukinumab) in Patients With Relapsing Multiple Sclerosis
Condition: Multiple Sclerosis
Interventions: Drug: Placebo;   Drug: AIN457
34 Recruiting Safety and Effectiveness of Belimumab in Systemic Lupus Erythematosus Registry
Condition: Systemic Lupus Erythematosus
Interventions: Biological: BENLYSTA;   Other: SLE treatment
35 Not yet recruiting Gene Therapy for B-Cell Non-Hodgkin Lymphoma Using CD19 CAR Gene Transduced T Lymphocytes
Condition: Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma
Interventions: Drug: Cyclophosphamide or Bendamustine;   Genetic: Dose Level -1;   Genetic: Dose Level 1;   Genetic: Dose Level 2;   Genetic: Dose Level 3
36 Recruiting International Guillain-Barré Syndrome Outcome Study
Conditions: Guillain-Barré Syndrome;   Miller Fisher Syndrome
Intervention:
37 Recruiting Prognostic Potential Cell Surface Marker and Pim-kinase in Patients With Hematologic Malignancies or Solid Tumors
Conditions: Solid Tumor;   Ovarian Cancer;   Non-small Cell Lung Cancer;   Chronic Lymphocytic Leukemia;   Burkitt's Lymphoma
Intervention:
38 Recruiting A Study to Evaluate the Effect of Belimumab on Vaccine Responses in Subjects With Systemic Lupus Erythematosus (SLE)
Condition: Systemic Lupus Erythematosus
Interventions: Biological: Belimumab plus Early Vaccination;   Biological: Belimumab plus Late Vaccination
39 Recruiting Severe Asthma Research Program - University of Virginia
Condition: Asthma
Intervention:
40 Recruiting Oral Bacteria and Immune System Problems Involved in Gum Disease (Periodontitis)
Conditions: Immune Defect;   Periodontal Disease
Intervention:

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