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19 studies found for:    Open Studies | "Hyperlipoproteinemia Type II"

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Open Studies | "Hyperlipoproteinemia Type II"
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Rank Status Study
1 Not yet recruiting Efficacy and Tolerability of Anacetrapib Added to Ongoing Lipid-Lowering Therapy in Adult Participants With Homozygous Familial Hypercholesterolemia (HoFH) (MK-0859-042 AM1)
Conditions: Hyperlipoproteinemia Type II;   Homozygous Familial Hypercholesterolemia
Interventions: Drug: Anacetrapib;   Drug: Placebo
2 Recruiting Study of REGN727 (SAR236553) in Patients With heFH (Heterozygous Familial Hypercholesterolemia) Who Are Not Adequately Controlled With Their LMT (Lipid-Modifying Therapy)
Condition: Heterozygous Familial Hypercholesterolemia
Interventions: Drug: LMT (atorvastatin, simvastatin, or rosuvastatin);   Drug: REGN727 (SAR236553);   Other: Placebo
3 Not yet recruiting Cardiovascular Disease in FH Heterozygous
Condition: Familial Hypercholesterolemia
Intervention:
4 Recruiting Atorvastatin Three Year Pediatric Study
Condition: Familial Hypercholesterolemia
Intervention: Drug: atorvastatin
5 Not yet recruiting Effect of Omega-3 Fatty Acid on Endothelial Function
Condition: Familial Hypercholesterolemia
Interventions: Drug: Omega-3;   Drug: placebo
6 Recruiting Efficacy and Safety of SAR236553 (REGN727) Versus Placebo on Top of Lipid-Modifying Therapy in Patients With Heterozygous Familial Hypercholesterolemia Not Adequately Controlled With Their Lipid-Modifying Therapy
Condition: Hypercholesterolemia
Interventions: Drug: SAR236553 (REGN727);   Other: placebo
7 Recruiting Reduction of LDL-C With PCSK9 Inhibition in Heterozygous Familial Hypercholesterolemia Disorder Study-2
Condition: Hyperlipidemia
Interventions: Drug: AMG 145;   Other: Placebo
8 Recruiting A Study of the Safety and Efficacy of Two Different Regimens of Mipomersen in Patients With Familial Hypercholesterolemia and Inadequately Controlled Low-Density Lipoprotein Cholesterol
Conditions: Hypercholesterolemia;   Coronary Heart Disease
Interventions: Drug: mipomersen sodium 200 mg;   Drug: Placebo;   Drug: mipomersen sodium 70 mg
9 Unknown † Evaluation of Chylomicrons Metabolism in Sub-Clinical Atherosclerosis in Patients Whit Heterozigous Familial Hypercholesterolemia (FH) Treated With Statin Plus Ezetimibe
Condition: Heterozigous Familial Hypercholesterolemia
Intervention: Drug: Statins and Ezetimibe
10 Recruiting Safety and Efficacy of the DALI LDL-adsorber and MONET-lipoprotein Filter
Conditions: Hypercholesterolemia, Familial;   LIPOPROTEIN TYPES--Lp SYSTEM Lp(a) HYPERLIPOPROTEINEMIA
Interventions: Device: DALI-adsorber;   Device: MONET-Lipoprotein filter
11 Recruiting Effect of CER-001 on Plaque Volume in Homozygous Familial Hypercholesterolemia (HoFH) Subjects
Condition: Homozygous Familial Hypercholesterolemia
Intervention: Drug: CER-001
12 Not yet recruiting A Study of the Safety and Efficacy of Anacetrapib (MK-0859) When Added to Ongoing Statin Therapy in Japanese Participants With Heterozygous Familial Hypercholesterolemia (MK-0859-050)
Condition: Heterozygous Familial Hypercholesterolemia (HeFH)
Interventions: Drug: Anacetrapib;   Drug: Placebo for anacetrapib
13 Unknown † Soy Food Intervention Trial
Condition: Familial Hypercholesterolemia
Interventions: Dietary Supplement: soy protein diet;   Dietary Supplement: rapeseed oil
14 Recruiting Trial Assessing Long Term USe of PCSK9 Inhibition in Subjects With Genetic LDL Disorders
Condition: Homozygous Familial Hypercholesterolemia or PCSK9 Mutations
Intervention: Drug: AMG 145
15 Recruiting Efficacy and Safety of SAR236553 (REGN727) Versus Placebo on Top of Lipid-Modifying Therapy in Patients With Heterozygous Familial Hypercholesterolemia (ODYSSEY High FH)
Condition: Hypercholesterolaemia
Interventions: Drug: SAR236553 (REGN727);   Drug: placebo
16 Not yet recruiting Postprandial Lipid Metabolism in Familial Hypercholesterolaemia:Effects of Fish Oils
Conditions: Hypertriglyceridaemia;   Familial Hypercholesterolaemia
Interventions: Dietary Supplement: Fish oil capsule;   Drug: HMG Coenzyme reductase
17 Recruiting The Rogosin Institute Homozygous Familial Hypercholesterolemia Repository
Condition: Homozygous Familial Hypercholesterolemia
Intervention:
18 Unknown † Effect of Rapeseed Oil and Sunflower Oil
Condition: Familial Hypercholesterolemia
Interventions: Dietary Supplement: rapeseed oil;   Dietary Supplement: sunflower oil
19 Recruiting Trial Evaluating PCSK9 Antibody in Subjects With LDL Receptor Abnormalities
Condition: Homozygous Familial Hypercholesterolemia
Interventions: Biological: AMG 145;   Other: Placebo
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† Indicates status has not been verified in more than two years