97 studies found for:    Open Studies | "Hypercholesterolemia"
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21 Recruiting Trial Assessing Long Term USe of PCSK9 Inhibition in Subjects With Genetic LDL Disorders
Condition: Severe Familial Hypercholesterolemia
Intervention: Biological: Evolocumab (AMG145)
22 Unknown  Addition of Ezetimibe (Ezetrol®) to Ongoing Therapy With Rosuvastatin (Crestor®) in HIV Positive Patients Not Reaching Cholesterol Targets
Conditions: Hypercholesterolemia;   HIV Infections
Interventions: Drug: Ezetimibe;   Drug: Rosuvastatin (standard care)
23 Recruiting Effect of Mipomersen on LDL-Cholesterol Levels in Patients Treated by Regular Apheresis
Conditions: Atherosclerosis;   LDL-hypercholesterolemia
Intervention: Drug: mipomersen
24 Unknown  Soy Food Intervention Trial
Condition: Familial Hypercholesterolemia
Interventions: Dietary Supplement: soy protein diet;   Dietary Supplement: rapeseed oil
25 Recruiting Pharmacokinetics And Relative Bioavailability Of PF-04950615 When Administered To The Abdomen, Thigh Or Upper Arm
Condition: Hypercholesterolemia
Interventions: Device: PF-04950615;   Biological: PF-04950615
26 Recruiting Open Label Study of Long Term Safety Evaluation of Alirocumab
Condition: Hypercholesterolemia
Intervention: Drug: Alirocumab SAR236553 (REGN727)
27 Recruiting Evaluation of ETC-1002 vs Placebo in Patients Receiving Ongoing Statin Therapy
Condition: Hypercholesterolemia
Interventions: Drug: ETC-1002;   Drug: Placebo
28 Recruiting To Compare the Effect of Concomitant Administration of Probucol and Cilostazol With Probucol Single Treatment on the Atherosclerosis Related Markers (Including the Thickness of the Achilles Tendon) and Evaluate Safety (Based on Atorvastatin Treatment) in Severe Hypercholesterolemia Subject
Condition: Severe Hypercholesterolemia
Intervention: Drug: Atorvastatin, Probucol, Cilostazol
29 Unknown  Effect of Rapeseed Oil and Sunflower Oil
Condition: Familial Hypercholesterolemia
Interventions: Dietary Supplement: rapeseed oil;   Dietary Supplement: sunflower oil
30 Not yet recruiting Effect of Omega-3 Fatty Acid on Endothelial Function
Condition: Familial Hypercholesterolemia
Interventions: Drug: Omega-3;   Drug: placebo
31 Recruiting Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care
Conditions: Infection;   Hypertension;   Anesthesia;   Pain;   Reflux;   Nausea;   Edema;   Hyperlipidemia;   Hypotension;   Hypercholesterolemia
Intervention: Drug: Ampicillin
32 Unknown  The Anti-Diabetic and Cholesterol-Lowering Effects of Cinnamon and Cassia Bark
Conditions: Type 2 Diabetes;   Hypercholesterolemia
Interventions: Dietary Supplement: Cinnamonforce;   Dietary Supplement: Placebo
33 Recruiting Efficacy and Safety of Lomitapide in Japanese Patients With HoFH on Concurrent Lipid-Lowering Therapy
Condition: Familial Hypercholesterolemia - Homozygous
Intervention: Drug: lomitapide
34 Recruiting GLobal Assessment of Plaque reGression With a PCSK9 antibOdy as Measured by intraVascular Ultrasound
Condition: Hypercholesterolemia
Interventions: Biological: Evolocumab (AMG 145);   Other: Placebo
35 Recruiting Effect of LDL-apheresis on PTX3 Plasma Levels in Hypercholesterolemic Patients
Condition: Hypercholesterolemia
Intervention: Procedure: LDL-apheresis
36 Unknown  Tolerability and Lipid Lowering Effect of Weekly/Biweekly Crestor in Statin Intolerant Patients Treated With Zetia
Condition: Hypercholesterolemia
Interventions: Drug: Rosuvastatin;   Drug: Ezetimibe
37 Recruiting Lentils as a Functional Food to Improve Glucose and Decrease Cardiovascular Risk
Conditions: Obesity;   Hypercholesterolemia
Interventions: Other: Cooked Lentils;   Other: Potato-Based Foods
38 Not yet recruiting Enhanced Multicenter Dietary Portfolio Study
Conditions: Cardiovascular Diseases;   Type 2 Diabetes;   Hypercholesterolemia
Interventions: Behavioral: Enhanced portfolio plus structured exercise;   Behavioral: High fiber diet plus routine exercise
39 Recruiting The Effects of Lowering Low-density Lipoprotein Cholesterol Levels to New Targets on Cardiovascular Complications in Peritoneal Dialysis Patients
Condition: Hypercholesterolemia
Intervention: Other: LDL-cholesterol
40 Recruiting Genetically Guided Statin Therapy
Conditions: Hypercholesterolemia;   HMG COA Reductase Inhibitor Adverse Reaction
Interventions: Genetic: Reporting for SLCO1B1*5 allele at randomization;   Genetic: Reporting for SLCO1B1*5 allele at the end;   Genetic: Genetic testing for SLCO1B1*5 allele

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Indicates status has not been verified in more than two years