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156 studies found for:    Open Studies | "Hydroxymethylglutaryl-CoA Reductase Inhibitors"

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1 Recruiting Vitamin D Replacement in Statin-Induced Myopathy
Condition: HMG COA Reductase Inhibitor Adverse Reaction
Interventions: Drug: Vitamin D (Cholecalciferol );   Drug: Placebo
2 Recruiting Statin Therapy to Improve Atherosclerosis in HIV Patients
Conditions: Cardiovascular Disease;   HIV;   Atherosclerosis;   Inflammation;   Statins, HMG-CoA;   HIV Infections
Interventions: Drug: atorvastatin;   Drug: Placebo
3 Recruiting Clinical Trial of CoQ10 for Mild-to-Moderate Statin-Associated Muscle Symptoms
Conditions: Pain;   Weakness;   Cramps;   Myalgia;   Side Effects of Statins
Interventions: Dietary Supplement: Coenzyme Q10;   Other: Placebo
4 Unknown † Association of Genetic Polymorphisms With Lipid Lowering Effects of Statin Therapy
Conditions: Statins, HMG-CoA;   Single Nucleotide Polymorphism
Intervention:
5 Not yet recruiting Muscle-Related Side Effects of Statins: Functional Impact, Mechanisms, and Potential Relief With Vitamin D Supplementation
Condition: HMG COA Reductase Inhibitor Adverse Reaction
Interventions: Drug: Vitamin D;   Drug: Placebo
6 Recruiting Evaluation of Patients With Statin Myopathy Using an N of 1 Trial Design
Condition: Statin Myopathy
Intervention: Drug: Individual-specific statin causing myopathy
7 Recruiting Evaluation of Ubiquinol on Mitochondrial Oxidative Capacity in Statin Patients Using 31PMRS
Conditions: Myopathy;   HMG COA Reductase Inhibitor Adverse Reaction;   Hypercholesterolemia
Interventions: Dietary Supplement: ubiquinol;   Dietary Supplement: placebo;   Drug: statin
8 Recruiting Early Use of Rosuvastatin in Acute Coronary Syndromes: Targeting Platelet-Leukocyte Interactions
Conditions: Acute Coronary Syndrome;   Angioplasty, Transluminal, Percutaneous Coronary;   Hydroxymethylglutaryl-CoA Reductase Inhibitors;   Blood Platelets
Interventions: Drug: rosuvastatin;   Drug: placebo
9 Unknown † Comparison of High-Dose Rosuvastatin Versus Low Statin Dose Plus Fenofibrate Versus Low Statin Dose Plus Niacin in the Treatment of Mixed Hyperlipidemia
Condition: Dyslipidemia
Interventions: Drug: High-dose rosuvastatin;   Drug: Statin plus fenofibrate;   Drug: Statin plus niacin ER/laropiprant
10 Unknown † The Association of Genetic Polymorphisms With Statin-Induced Myopathy.
Conditions: Rhabdomyolysis;   Myopathy
Intervention: Genetic: DNA
11 Recruiting Statin Therapy In Cardiac Surgery
Conditions: Atrial Fibrillation;   Myocardium; Injury
Interventions: Drug: Rosuvastatin;   Drug: Placebo
12 Recruiting A Study to Evaluate Fenofibrate Combination With Statin in Chinese Patients With Dyslipidemic
Conditions: Dyslipidemias;   Cardiovascular Diseases;   Hypertriglyceridemia
Intervention: Drug: fenofibrate
13 Recruiting Benefit of CoQ-10 in Patients on Statins
Conditions: Pain;   Soreness;   Weakness;   Fatigue
Interventions: Dietary Supplement: Co-enzyme Q-10;   Dietary Supplement: Placebo
14 Recruiting Investigate Effect on Mean IMT of Probucol And/or CilosTazol in Patients With Coronary Heart dIsease Taking HMGCoA Reductase Inhibitor Therapy
Condition: Hyperlipidemias
Interventions: Drug: HMGCoA reductase inhibitor;   Drug: HMGCoA reductase inhibitor + probucol;   Drug: HMGCA reductase inhibitor + probucol + cilostazol
15 Recruiting Statin Recapture Therapy Before Coronary Artery Bypass Grafting
Condition: Coronary Artery Disease
Interventions: Drug: Statin Recapture Therapy;   Drug: Placebo
16 Recruiting Ischemia/Reperfusion Injury of Human Endothelium: Role of Glucose and Statins
Condition: Hyperglycemia
Interventions: Drug: 5% dextrose;   Drug: vitamin C;   Drug: Simvastatin;   Drug: L-NMMA
17 Recruiting Statins in Children With Type 1 Diabetes and Hypercholesterolemia
Conditions: Diabetes Mellitus, Insulin-Dependent;   Hypercholesterolemia
Interventions: Drug: Atorvastatin;   Drug: Atorvastatin Placebo
18 Recruiting Paroxysmal Atrial Fibrillation: Role of Inflammation, Oxidative Stress Injury and Effect of Statins
Condition: Atrial Fibrillation
Interventions: Drug: Simvastatin;   Drug: Placebo
19 Unknown † Statins and Cerebral Blood Flow in Subarachnoid Hemorrhage (SAH)
Condition: Subarachnoid Hemorrhage
Interventions: Drug: Simvastatin, 80 mg/day for 21 days;   Drug: placebo
20 Unknown † China Intensive Lipid Lowering With Statins in Acute Coronary Syndrome
Condition: Acute Coronary Syndrome
Intervention: Drug: Atorvastatin
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† Indicates status has not been verified in more than two years