155 studies found for:    Open Studies | "Hydroxymethylglutaryl-CoA Reductase Inhibitors"
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Open Studies | "Hydroxymethylglutaryl-CoA Reductase Inhibitors" (155 records)
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Rank Status Study
1 Unknown  Vitamin D Replacement in Statin-Induced Myopathy
Condition: HMG COA Reductase Inhibitor Adverse Reaction
Interventions: Drug: Vitamin D (Cholecalciferol );   Drug: Placebo
2 Recruiting Genetically Guided Statin Therapy
Conditions: Hypercholesterolemia;   HMG COA Reductase Inhibitor Adverse Reaction
Interventions: Genetic: Reporting for SLCO1B1*5 allele at randomization;   Genetic: Reporting for SLCO1B1*5 allele at the end;   Genetic: Genetic testing for SLCO1B1*5 allele
3 Unknown  Association of Genetic Polymorphisms With Lipid Lowering Effects of Statin Therapy
Conditions: Statins, HMG-CoA;   Single Nucleotide Polymorphism
Intervention:
4 Unknown  Muscle-Related Side Effects of Statins: Functional Impact, Mechanisms, and Potential Relief With Vitamin D Supplementation
Condition: HMG COA Reductase Inhibitor Adverse Reaction
Interventions: Drug: Vitamin D;   Drug: Placebo
5 Unknown  Evaluation of Patients With Statin Myopathy Using an N of 1 Trial Design
Condition: Statin Myopathy
Intervention: Drug: Individual-specific statin causing myopathy
6 Recruiting Evaluation of Ubiquinol on Mitochondrial Oxidative Capacity in Statin Patients Using 31PMRS
Conditions: Myopathy;   HMG COA Reductase Inhibitor Adverse Reaction;   Hypercholesterolemia
Interventions: Dietary Supplement: ubiquinol;   Dietary Supplement: placebo;   Drug: statin
7 Recruiting Effect of Vitamin D Supplementation on Exercise Adaptations in Patients on Statin Therapy
Condition: [X]Statin Causing Adverse Effect in Therapeutic Use
Interventions: Drug: vitaminD;   Drug: Simvastatin;   Drug: Placebo
8 Recruiting Low-dose Statins and Nutraceuticals in High-intensity Statin-intolerant Patients
Condition: Coronary Artery Disease
Intervention: Drug: Association low-dose statin and nutraceuticals
9 Not yet recruiting Single Dose of Atorvastatin and Circulating Endothelial Microparticles
Conditions: Endothelium;   Hydroxymethylglutaryl-CoA Reductase Inhibitors
Interventions: Drug: atorvastatin;   Drug: placebo
10 Unknown  Comparison of High-Dose Rosuvastatin Versus Low Statin Dose Plus Fenofibrate Versus Low Statin Dose Plus Niacin in the Treatment of Mixed Hyperlipidemia
Condition: Dyslipidemia
Interventions: Drug: High-dose rosuvastatin;   Drug: Statin plus fenofibrate;   Drug: Statin plus niacin ER/laropiprant
11 Unknown  The Association of Genetic Polymorphisms With Statin-Induced Myopathy.
Conditions: Rhabdomyolysis;   Myopathy
Intervention: Genetic: DNA
12 Unknown  Benefit of CoQ-10 in Patients on Statins
Conditions: Pain;   Soreness;   Weakness;   Fatigue
Interventions: Dietary Supplement: Co-enzyme Q-10;   Dietary Supplement: Placebo
13 Recruiting Investigate Effect on Mean IMT of Probucol And/or CilosTazol in Patients With Coronary Heart dIsease Taking HMGCoA Reductase Inhibitor Therapy
Condition: Hyperlipidemias
Interventions: Drug: HMGCoA reductase inhibitor;   Drug: HMGCoA reductase inhibitor + probucol;   Drug: HMGCA reductase inhibitor + probucol + cilostazol
14 Recruiting Statin Recapture Therapy Before Coronary Artery Bypass Grafting
Condition: Coronary Artery Disease
Interventions: Drug: Statin Recapture Therapy;   Drug: Placebo
15 Unknown  Paroxysmal Atrial Fibrillation: Role of Inflammation, Oxidative Stress Injury and Effect of Statins
Condition: Atrial Fibrillation
Interventions: Drug: Simvastatin;   Drug: Placebo
16 Recruiting Statin Therapy in the Treatment of Sepsis
Condition: Septic Shock
Interventions: Drug: Simvastatin;   Drug: Placebo
17 Unknown  China Intensive Lipid Lowering With Statins in Acute Coronary Syndrome
Condition: Acute Coronary Syndrome
Intervention: Drug: Atorvastatin
18 Recruiting Ezetimibe Versus Nutraceuticals in Statin-intolerant Patients
Condition: Coronary Artery Disease
Interventions: Drug: Ezetimibe;   Drug: Nutraceuticals
19 Unknown  Statin Effects on Beta-Amyloid and Cerebral Perfusion in Adults at Risk for Alzheimer's Disease
Condition: Alzheimer's Disease
Interventions: Drug: Simvastatin;   Drug: Placebo
20 Not yet recruiting Randomized Clinical Trial of RN316 (PF-04950615) in Subjects Who Are Intolerant to Statins
Condition: Hyperlipidemia
Interventions: Drug: PF-04950615;   Drug: Atorvastatin;   Other: Placebo for PF-04950615;   Other: Placebo for atorvastatin

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Indicates status has not been verified in more than two years