29 studies found for:    Open Studies | "Herpes Simplex"
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Rank Status Study
1 Recruiting Study of the Safety of a Particular Herpes Vaccine in Adults With or Without Herpes Infection
Conditions: Herpes Genitalis;   Herpes Simplex Virus;   Herpes Simplex Virus Vaccines;   HSV Vaccines;   Herpesvirus Vaccines
Interventions: Biological: Injection;   Procedure: Blood Draw;   Procedure: Clinical evaluation of herpes simplex diseases;   Procedure: Self swabbing for asymptomatic viral shedding;   Procedure: Collection of cervicovaginal secretions
2 Recruiting The Flocked Swab and the Traditional Fiber Swab for the Diagnosis of the Herpes Simplex Epithelial Keratitis
Condition: Herpes Simplex Keratitis
Intervention: Procedure: Corneal sampling
3 Not yet recruiting A Multiple Ascending Dose-Finding Pharmacokinetic and Pharmacodynamic Study of a Novel Antiviral Drug in Infants With Neonatal Herpes Simplex Virus (HSV)
Condition: Herpes Simplex Virus
Interventions: Drug: Novel Antiviral Drug;   Drug: Placebo
4 Recruiting Identification of Herpes Simplex Virus (HSV) Shedding in the Female Genital Tract of Pregnant and Nonpregnant Women by GeneXpert PCR, Routine PCR, and Culture
Condition: Herpes Simplex Virus
Intervention: Device: Genexpert assay
5 Unknown  Phase III Randomized Study of Oral Acyclovir in Infants With Herpes Simplex Virus Infection Involving the Central Nervous System
Condition: Herpes Simplex
Intervention: Drug: acyclovir
6 Recruiting Safety and Efficacy Trial of DNA Vaccines to Treat Genital Herpes in Adults
Condition: Genital Herpes Simplex Type 2
Interventions: Biological: VCL-HB01;   Biological: VCL-HM01;   Biological: PBS
7 Unknown  Can Valacyclovir Attenuate Inflammation in Antiretroviral-Treated HIV-Infected Individuals With Herpes Simplex Virus Type 2?
Conditions: HIV Infections;   Herpes Simplex
Interventions: Drug: Valacyclovir;   Drug: Placebo
8 Unknown  30-Day Trial of Oral Valtrex or Valtrex Plus Aspirin on Shedding of HSV DNA in Tears and Saliva of Volunteers
Condition: Herpes Simplex
Interventions: Drug: valacyclovir hydrochloride;   Drug: placebo;   Drug: valacyclovir plus aspirin
9 Recruiting Effect of Tenofovir on Genital Herpes Simplex Virus (HSV) Shedding
Condition: Herpes Simplex Type II
Interventions: Drug: Tenofovir;   Drug: placebo gel;   Drug: tenofovir disoproxil fumarate (TDF);   Drug: placebo tablets
10 Recruiting Evaluation of Cold Sore Treatments on UV Induced Cold Sores
Condition: Oral Herpes Simplex
Interventions: Drug: Matching Placebo;   Drug: BTL-TML-HSV
11 Recruiting Interferon Responses in Eczema Herpeticum (ADEH)
Conditions: Atopic Dermatitis;   Eczema Herpeticum;   Herpes Simplex Infections;   Eczema Vaccinatum
Intervention:
12 Recruiting Improving Blood Safety and HIV Testing in Brazil
Conditions: HIV;   Herpes Simplex 2;   Hepatitis C;   Hepatitis B;   Chagas Disease
Interventions: Behavioral: HIV Counseling and Testing;   Behavioral: Blood Donation
13 Not yet recruiting Dose Ranging Safety and Efficacy of Therapeutic HSV-2 Vaccine
Condition: Genital Herpes Simplex Type 2
Interventions: Biological: Matrix-M2 Adjuvant;   Biological: GEN-003 Vaccine
14 Recruiting A Phase I Study of Recombinant hGM-CSF Herpes Simplex Virus to Treat Cancer
Conditions: Melanoma;   Liver Cancer;   Pancreatic Cancer;   Lung Cancer
Intervention: Biological: Recombinant hGM-CSF Herpes Simplex Virus Injection
15 Recruiting Safety and Effectiveness of Tenofovir Gel in the Prevention of Human Immunodeficiency Virus (HIV-1) Infection in Women and the Effects of Tenofovir Gel on the Incidence of Herpes Simplex Virus (HSV-2) Infection
Condition: HIV Prevention
Interventions: Drug: Tenofovir gel;   Drug: Universal placebo gel
16 Recruiting Can Valacyclovir Delay the Need for Initiation of Human Immunodeficiency Virus (HIV) Treatment in HIV-infected Individuals With Herpes Simplex Virus Type 2?
Conditions: HIV Infection;   Herpesvirus 2, Human;   HIV Infections
Interventions: Drug: valacyclovir;   Drug: Placebo
17 Recruiting Efficacy of Oral Famciclovir 125mg Comparing to Aciclovir 200 mg Treatment in Patients With Active Recurrent Genital Herpes
Condition: GENITAL HERPES
Interventions: Drug: Famciclovir;   Drug: Aciclovir
18 Recruiting Herpes Simplex Type 1 Suppression in Hepatitis C
Condition: Chronic Hepatitis C Infection
Interventions: Drug: Valacyclovir;   Drug: Placebo
19 Recruiting TK008: Efficacy Study on the Strategy of Herpes Simplex Virus Thymidine Kinase Donor Lymphocytes to Treat Patients With High Risk Acute Leukemia
Condition: High Risk Acute Leukemia
Interventions: Genetic: HSV-Tk;   Other: T cell repletion strategies
20 Recruiting Oncolytic HSV-1716 in Treating Younger Patients With Refractory or Recurrent High Grade Glioma That Can Be Removed By Surgery
Conditions: Recurrent Childhood Anaplastic Astrocytoma;   Recurrent Childhood Anaplastic Oligoastrocytoma;   Recurrent Childhood Anaplastic Oligodendroglioma;   Recurrent Childhood Giant Cell Glioblastoma;   Recurrent Childhood Glioblastoma;   Recurrent Childhood Gliomatosis Cerebri;   Recurrent Childhood Gliosarcoma
Interventions: Biological: oncolytic HSV-1716;   Drug: dexamethasone;   Procedure: therapeutic conventional surgery;   Other: laboratory biomarker analysis

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Indicates status has not been verified in more than two years