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12 studies found for:    Open Studies | "Hepatoblastoma"

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Rank Status Study
1 Recruiting Hepatoblastoma Biology Study and Tissue Bank
Condition: Hepatoblastoma
Intervention: Procedure: Biology Study and Tissue Banking
2 Recruiting Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Liver Cancer
Conditions: Childhood Hepatoblastoma;   Stage I Childhood Liver Cancer;   Stage II Childhood Liver Cancer;   Stage III Childhood Liver Cancer;   Stage IV Childhood Liver Cancer
Interventions: Procedure: therapeutic conventional surgery;   Drug: cisplatin;   Drug: fluorouracil;   Drug: vincristine sulfate;   Drug: doxorubicin hydrochloride;   Drug: irinotecan hydrochloride;   Procedure: liver transplantation;   Other: laboratory biomarker analysis
3 Recruiting A Phase I Dose Finding and Safety Study of Oral LDE225 in Children and a Phase II Portion to Assess Preliminary Efficacy in Recurrent or Refractory MB
Conditions: Medulloblastoma,;   Rhabdomyosarcoma,;   Neuroblastoma,;   Hepatoblastoma,;   High Grade Glioma,;   Astrocytoma
Intervention: Drug: LDE225
4 Unknown † Tandem Peripheral Blood Stem Cell (PBSC) Rescue for High Risk Solid Tumors
Conditions: Ewing's Sarcoma;   Soft Tissue Sarcoma;   Hepatoblastoma;   Hodgkin's Disease;   Germ Cell Tumor
Intervention: Drug: High-Dose Chemotherapy with Tandem PBSC Rescue.
5 Recruiting Aflac ST0901 CHOANOME - Sirolimus in Solid Tumors
Conditions: Ewing's Sarcoma;   Osteosarcoma;   Astrocytoma;   Atypical Teratoid/Rhabdoid Tumor;   Ependymoma;   Germ Cell Tumor;   Glioma;   Medulloblastoma;   Rhabdoid Tumor;   Retinoblastoma;   Clear Cell Sarcoma;   Renal Cell Carcinoma;   Wilms Tumor;   Hepatoblastoma;   Neuroblastoma;   Rhabdomyosarcoma
Intervention: Drug: sirolimus
6 Recruiting Alisertib in Treating Young Patients With Recurrent or Refractory Solid Tumors or Leukemia
Conditions: Childhood Hepatoblastoma;   Previously Treated Childhood Rhabdomyosarcoma;   Recurrent Childhood Acute Lymphoblastic Leukemia;   Recurrent Childhood Acute Myeloid Leukemia;   Recurrent Childhood Malignant Germ Cell Tumor;   Recurrent Childhood Rhabdomyosarcoma;   Recurrent Childhood Soft Tissue Sarcoma;   Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor;   Recurrent Neuroblastoma;   Recurrent Osteosarcoma;   Recurrent Wilms Tumor and Other Childhood Kidney Tumors
Interventions: Drug: alisertib;   Other: pharmacological study;   Other: laboratory biomarker analysis
7 Recruiting Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ Cell Tumor, Hepatoblastoma, Medulloblastoma, Neuroblastoma, Osteosarcoma, or Other Malignancy
Conditions: Brain and Central Nervous System Tumors;   Childhood Germ Cell Tumor;   Extragonadal Germ Cell Tumor;   Liver Cancer;   Neuroblastoma;   Ototoxicity;   Ovarian Cancer;   Sarcoma
Interventions: Drug: sodium thiosulfate;   Procedure: examination
8 Unknown † Cisplatin With or Without Sodium Thiosulfate in Treating Young Patients With Stage I, Stage II, or Stage III Childhood Liver Cancer
Conditions: Liver Cancer;   Ototoxicity
Interventions: Drug: cisplatin;   Drug: sodium thiosulfate;   Genetic: gene rearrangement analysis;   Genetic: microarray analysis;   Genetic: proteomic profiling;   Other: immunohistochemistry staining method;   Other: laboratory biomarker analysis;   Procedure: adjuvant therapy;   Procedure: neoadjuvant therapy;   Procedure: therapeutic conventional surgery
9 Recruiting A Phase II Trial of Reduced Intensity Conditioning and Haploidentical BMT for High-risk Solid Tumors
Condition: Refractory and/or Relapsed Metastatic Solid Tumors
Interventions: Drug: Cyclophosphamide;   Drug: Fludarabine;   Radiation: low dose total body irradiation;   Drug: Melphalan;   Drug: Sirolimus
10 Recruiting Cyproheptadine in Preventing Weight Loss in Children Receiving Chemotherapy for Cancer
Condition: Cancer
Interventions: Drug: cyproheptadine hydrochloride;   Other: placebo
11 Recruiting Collecting and Storing Tissue From Young Patients With Cancer
Condition: Cancer
Interventions: Genetic: DNA analysis;   Genetic: reverse transcriptase-polymerase chain reaction;   Other: biologic sample preservation procedure;   Other: flow cytometry;   Other: laboratory biomarker analysis
12 Unknown † Biomarkers in Tissue Samples From Young Patients With Liver Cancer
Condition: Liver Cancer
Interventions: Genetic: RNA analysis;   Genetic: gene expression analysis;   Genetic: microarray analysis;   Genetic: nucleic acid sequencing;   Other: laboratory biomarker analysis
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† Indicates status has not been verified in more than two years