59 studies found for:    Open Studies | "Hemophilia A"
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Rank Status Study
21 Recruiting A Phase 1 Study of an Investigational Drug, ALN-AT3SC, in Healthy Volunteers and Hemophilia A or B Patients
Conditions: Hemophilia A;   Hemophilia B
Interventions: Drug: ALN-AT3SC;   Drug: Sterile Normal Saline (0.9% NaCl)
22 Recruiting Safety and Efficacy of Turoctocog Alfa Pegol (N8-GP) in Previously Untreated Patients With Haemophilia A
Conditions: Congenital Bleeding Disorder;   Haemophilia A
Intervention: Drug: turoctocog alfa pegol
23 Recruiting A Phase 1 Safety, Pharmacokinetics And Pharmacodynamics Study Of PF-05280602, A Recombinant Factor VIIa Variant (813d), In Adult Subjects With Hemophilia A Or B
Condition: Hemophilia A
Intervention: Biological: PF-05280602
24 Recruiting An Open-label Safety, Efficacy and Pharmacokinetic Study of a Recombinant FVIII Compared to Recombinant Human Antihemophilic FVIII in Patients With Severe Hemophilia A
Condition: Hemophilia A
Intervention: Biological: Recombinant Factor VIII (rFVIII)
25 Not yet recruiting Assess the Efficacy and Safety of Personalized Prophylaxis Human-cl rhFVIII in Patients With Severe Haemophilia A
Condition: Severe Haemophilia A
Intervention: Biological: Human cl rhFVIII
26 Recruiting Covalent Tolerance Induction to Factor VIII-Prediction of Inhibitors in Hemophilia
Condition: Hemophilia A
Intervention:
27 Recruiting Pharmacokinetic, Efficacy, and Safety Study of Recombinant Factor VIII Single Chain (rVIII-SingleChain) in Children With Severe Hemophilia A
Condition: Congenital Hemophilia A
Intervention: Biological: rVIII-SingleChain
28 Recruiting A Phase III Study on the Safety, Pharmacokinetics and Efficacy of Coagulation Factor VIIa (Recombinant) in Congenital Hemophilia A or B Patients With Inhibitors to Factor VIII or IX
Conditions: Hemophilia A With Inhibitors;   Hemophilia B With Inhibitors
Intervention: Biological: Coagulation Factor VIIa (Recombinant)
29 Unknown  Personalized Prediction of Tolerance and Immunogenicity in Hemophilia
Condition: Hemophilia A
Intervention:
30 Recruiting Study of Safety And Efficacy Of ReFacto AF In Previously Untreated Hemophilia A Patients In The Usual Care Setting
Condition: Hemophilia A
Intervention: Procedure: Laboratory Tests
31 Recruiting Survey of Inhibitors in Plasma-Product Exposed Toddlers
Condition: Hemophilia A
Interventions: Drug: PLASMA DERIVED Factor VIII;   Drug: Recombinant FVIII
32 Not yet recruiting Hemophilia Inhibitor Prevention (INHIBIT) Trial
Condition: Severe Hemophilia A
Intervention: Drug: Long-acting recombinant factor VIII Fc fusion protein
33 Recruiting BAY81-8973 Pediatric Safety and Efficacy Trial
Condition: Haemophilia A
Intervention: Biological: Recombinant Factor VIII (BAY81-8973)
34 Recruiting Thrombin Generation Assay (TGA) as Predictive Test for Haemostatic. Effectiveness of FVIII Concentrates in Haemophiliac A With Inhibitors
Condition: Severe Hemophilia A With Inhibitor
Intervention: Other: TGA (Thrombin generation Assay)
35 Unknown  A Prospective, Randomized, Cross-Over Study of an Activated Prothrombin Complex Concentrate for Secondary Prophylaxis in Patients With Hemophilia A and Inhibitors
Condition: Hemophilia A With Inhibitors
Intervention: Drug: activated prothrombin complex concentrate (FEIBA)
36 Recruiting China ADVATE PTP Study
Condition: Hemophilia A
Intervention: Biological: Octocog alfa (recombinant human coagulation factor VIII)
37 Unknown  Non Neutralizing Antibodies: Prevalence and Characterization
Condition: Hemophilia A
Intervention: Biological: blood test
38 Recruiting Study Evaluating Prophylaxis Treatment & Characterizing Efficacy, Safety, & PK Of B-Domain Deleted Recombinant FVIII
Condition: Hemophilia A
Intervention: Biological: Moroctocog alfa (AF-CC)
39 Recruiting BAX 855 Pediatric Study
Condition: Hemophilia A
Interventions: Biological: Antihemophilic Factor (Recombinant) - Plasma/Albumin Free Method;   Biological: PEGylated Recombinant Factor VIII
40 Not yet recruiting Case-control Pilot Study of the Immune Modulating Effect of FEIBA on Patients With Haemophilia A and Inhibitors
Condition: Severe Haemophilia A With Inhibitors
Intervention:

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Indicates status has not been verified in more than two years