59 studies found for:    Open Studies | "Eye Neoplasms"
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Rank Status Study
21 Recruiting Trametinib With or Without GSK2141795 in Treating Patients With Metastatic Uveal Melanoma
Conditions: Ciliary Body and Choroid Melanoma, Medium/Large Size;   Ciliary Body and Choroid Melanoma, Small Size;   Extraocular Extension Melanoma;   Iris Melanoma;   Metastatic Intraocular Melanoma;   Recurrent Intraocular Melanoma;   Stage IV Intraocular Melanoma
Interventions: Drug: trametinib;   Drug: Akt inhibitor GSK2141795;   Other: pharmacological study;   Other: laboratory biomarker analysis
22 Recruiting A Study of Sorafenib in Patients With Chemonaive Metastatic Uveal Melanoma
Condition: Uveal Melanoma
Interventions: Drug: Placebo;   Drug: Sorafenib
23 Unknown  Combined PET/CT Imaging for the Early Detection of Ocular Melanoma Metastasis Compared to CT Scanning Alone
Conditions: Ocular Melanoma;   Choroidal Melanoma;   Uveal Melanoma
Intervention:
24 Unknown  Quality of Life in Children Cured of Retinoblastoma
Condition: Retinoblastoma
Intervention:
25 Not yet recruiting Intra-arterial Melphalan in Treating Younger Patients With Unilateral Retinoblastoma
Condition: Intraocular Retinoblastoma
Intervention: Drug: melphalan
26 Recruiting Aflac ST0901 CHOANOME - Sirolimus in Solid Tumors
Conditions: Ewing's Sarcoma;   Osteosarcoma;   Astrocytoma;   Atypical Teratoid/Rhabdoid Tumor;   Ependymoma;   Germ Cell Tumor;   Glioma;   Medulloblastoma;   Rhabdoid Tumor;   Retinoblastoma;   Clear Cell Sarcoma;   Renal Cell Carcinoma;   Wilms Tumor;   Hepatoblastoma;   Neuroblastoma;   Rhabdomyosarcoma
Intervention: Drug: sirolimus
27 Recruiting Protocol for the Study and Treatment of Participants With Intraocular Retinoblastoma
Condition: Retinoblastoma
Interventions: Drug: vincristine;   Drug: topotecan;   Drug: filgrastim;   Drug: PEG-filgrastim;   Drug: carboplatin;   Other: focal therapy;   Drug: etoposide;   Drug: cyclophosphamide;   Drug: MESNA;   Drug: doxorubicin;   Procedure: enucleation;   Radiation: external beam radiation
28 Recruiting Intra-arterial Chemotherapy for the Treatment of Intraocular Retinoblastoma
Condition: Retinoblastoma
Intervention: Drug: Melphalan hydrochloride
29 Recruiting Vascular Response to Brachytherapy Using Functional OCT
Condition: Uveal Melanoma
Intervention:
30 Unknown  Sunitinib, Tamoxifen, and Cisplatin in Treating Patients With High-Risk Ocular Melanoma
Condition: Intraocular Melanoma
Interventions: Drug: cisplatin;   Drug: sunitinib malate;   Drug: tamoxifen citrate;   Procedure: adjuvant therapy
31 Recruiting Cabozantinib-S-Malate Compared With Temozolomide or Dacarbazine in Treating Patients With Melanoma of the Eye
Conditions: Ciliary Body and Choroid Melanoma, Medium/Large Size;   Ciliary Body and Choroid Melanoma, Small Size;   Iris Melanoma;   Metastatic Intraocular Melanoma;   Recurrent Intraocular Melanoma;   Stage IIIA Intraocular Melanoma;   Stage IIIB Intraocular Melanoma;   Stage IIIC Intraocular Melanoma;   Stage IV Intraocular Melanoma
Interventions: Drug: cabozantinib-s-malate;   Drug: temozolomide;   Drug: dacarbazine;   Other: laboratory biomarker analysis
32 Recruiting Adoptive T Cell Therapy for Metastatic Ocular Melanoma
Conditions: Metastatic Ocular Melanoma;   Metastatic Uveal Melanoma
Interventions: Drug: Aldesleukin;   Drug: Cyclophosphamide;   Drug: Fludarabine;   Drug: Tumor Infiltrating Lymphocytes
33 Not yet recruiting Dendritic Cells Plus Autologous Tumor RNA in Uveal Melanoma
Condition: Uveal Melanoma, Monosomy 3 Positive, no Evidence for Metastases.
Intervention: Biological: Autologous Dendritic Cells loaded with autologous Tumor RNA
34 Recruiting Pilot Study of Topotecan/Vincristine With Subconjunctival Carboplatin for Patients With Bilateral Retinoblastoma
Condition: Retinoblastoma
Interventions: Drug: subtenon Carboplatin;   Drug: Topotecan Hydrochloride;   Drug: Vincristine;   Drug: Filgrastim
35 Recruiting RAD001 (Everolimus) and Pasireotide (SOM230) LAR in Patients With Advanced Uveal Melanoma
Condition: Uveal Melanoma
Intervention: Drug: RAD001 (Everolimus) and Pasireotide (SOM230) LAR
36 Recruiting Vorinostat in Treating Patients With Metastatic Melanoma of the Eye
Conditions: Metastatic Intraocular Melanoma;   Recurrent Intraocular Melanoma
Interventions: Drug: vorinostat;   Other: laboratory biomarker analysis
37 Not yet recruiting Phase II Study Temozolomide for Retinoblastoma Metastatic to the Central Nervous System for Patients From Guatemala
Condition: Retinoblastoma
Intervention: Drug: Temozolomide
38 Not yet recruiting Selumetinib (AZD6244: ARRY-142886) (Hyd-Sulfate) in Metastatic Uveal Melanoma (SUMIT)
Conditions: Metastatic;   Uveal Melanoma
Interventions: Drug: 75mg selumetinib;   Drug: placebo;   Drug: Dacarbazine
39 Not yet recruiting Dexamethasone Intravitreal Implant for Treatment of Macular Edema After Plaque Radiotherapy of Uveal Melanoma
Conditions: Macular Edema;   Cystoid Macular Edema;   Uveal Melanoma;   Radiation Maculopathy;   Radiation Retinopathy
Interventions: Drug: Ozurdex;   Drug: Bevacizumab
40 Recruiting Use of Racotumomab in Patients With Pediatric Tumors Expressing N-glycolylated Gangliosides
Conditions: Neuroblastoma;   Ewing's Sarcoma;   Wilm's Tumor;   Retinoblastoma;   Glioma
Intervention: Drug: racotumomab

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Indicates status has not been verified in more than two years