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51 studies found for:    Open Studies | "Down Syndrome"
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Rank Status Study
21 Unknown  Glucose Metabolic, Amyloid, and Tau Brain Imaging in Down Syndrome and Dementia
Conditions: Down Syndrome;   Alzheimer's Disease
Intervention:
22 Recruiting Comparison of Bispectral Index Values in Patients With and Without Down's Syndrome
Condition: Down Syndrome
Intervention: Device: monitoring BIS in both groups
23 Recruiting Non Invasive Prenatal Diagnosis of Trisomy 21 by Genetic Analysis of Circulating Fetal Cells
Condition: Trisomy 21
Intervention: Other: sample blood
24 Recruiting A Study of RG1662 in Adults and Adolescents With Down Syndrome (CLEMATIS)
Condition: Down Syndrome
Interventions: Drug: Placebo;   Drug: RG1662
25 Recruiting A 4-Week Safety Study of Oral ELND005 in Young Adults With Down Syndrome Without Dementia
Condition: Down Syndrome
Interventions: Drug: ELND005;   Drug: Placebo
26 Recruiting Assessment of Bone Density and Bone Turnover Markers in Patients With Down Syndrome and Comparison to the Ts65Dn Model
Condition: Down Syndrome
Intervention: Genetic: Skeletal Status Assessment of a Down Syndrome Population
27 Recruiting A Screening Protocol to Assess Adults and Adolescents With Down Syndrome for Eligibility For Upcoming Study of RG1662 (Study BP27832)
Condition: Down Syndrome
Intervention:
28 Unknown  Frequency of Metabolic Syndrome in Down Syndrome Patients
Conditions: Metabolic Syndrome X;   Down Syndrome
Intervention:
29 Recruiting Specimen Collection From Pregnant Women at Increased Risk for Fetal Aneuploidy
Conditions: Down Syndrome;   Fetal Aneuploidy
Intervention:
30 Recruiting Clinical Evaluation of the SEQureDx T21 Test In High Risk Pregnancies
Conditions: Down Syndrome;   Fetal Aneuploidy
Intervention:
31 Recruiting Non-Invasive Chromosomal Evaluation of Trisomy Study
Conditions: Fetal Aneuploidy;   Trisomy 21;   Trisomy 18;   Trisomy 13;   Down Syndrome
Intervention:
32 Recruiting Noninvasive Screening for Affected Pregnancies: Assay Development & Optimization in Affected Pregnancies
Conditions: Down Syndrome;   Aneuploidy
Intervention: Other: Maternal blood draw of 30 to 50ml
33 Recruiting Development of Non-invasive Prenatal Test for Microdeletion and Other Genetic Syndromes Based on Cell Free DNA
Conditions: Microdeletion Syndromes;   Trisomy 21;   Trisomy 18;   Trisomy 13;   Sex Chromosome Abnormalities
Intervention:
34 Not yet recruiting The Effect of Bifocals in Children With Down Syndrome
Conditions: Visual Acuity at Near;   Accuracy of Accommodation;   Prevention of Strabismus;   Task Readiness
Interventions: Device: bifocals;   Device: single vision glasses
35 Recruiting High Risk Multiple Gestation Study
Conditions: Trisomy 13;   Trisomy 18;   Trisomy 21;   Sex Chromosome Abnormalities
Intervention:
36 Recruiting Multiple Gestation Study
Conditions: Trisomy 13;   Trisomy 18;   Trisomy 21;   Sex Chromosome Abnormalities
Intervention:
37 Recruiting Clinical Performance of the MaterniT21 PLUS LDT in Multiple Gestation Pregnancies
Conditions: Down Syndrome;   Edwards Syndrome;   Patau Syndrome;   Turner Syndrome
Intervention:
38 Not yet recruiting DIR/ Floortime™ Parent Training Intervention for the Children With Developmental Disabilities
Conditions: Cerebral Palsy;   Down's Syndrome;   Delayed Development
Interventions: Behavioral: Parent training;   Behavioral: Routine care
39 Unknown  Normalization of dyrk1A and APP Function as an Approach to Improve Cognitive Performance and Decelerate AD Progression in DS Subjects: Epigallocatechin Gallate as Therapeutic Tool
Condition: Down Syndrome (DS)
Intervention: Dietary Supplement: Epigallocatechin-3-gallate (EGCG)
40 Unknown  Non-Invasive Determination of Fetal Chromosome Abnormalities
Conditions: Down Syndrome (Trisomy 21);   Edward's Syndrome (Trisomy 18);   Patau Syndrome (Trisomy 13);   Klinefelter Syndrome (47, XXY);   and Other Chromosome;   Abnormalities.
Intervention:

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Indicates status has not been verified in more than two years