47 studies found for:    Open Studies | "Down Syndrome"
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Rank Status Study
21 Recruiting A Study of RG1662 in Adults and Adolescents With Down Syndrome (CLEMATIS)
Condition: Down Syndrome
Interventions: Drug: RG1662;   Drug: Placebo
22 Recruiting A 4-Week Safety Study of Oral ELND005 in Young Adults With Down Syndrome Without Dementia
Condition: Down Syndrome
Interventions: Drug: ELND005;   Drug: Placebo
23 Recruiting A Screening Protocol to Assess Adults and Adolescents With Down Syndrome for Eligibility For Upcoming Study of RG1662 (Study BP27832)
Condition: Down Syndrome
Intervention:
24 Recruiting Non-Invasive Chromosomal Evaluation of Trisomy Study
Conditions: Fetal Aneuploidy;   Trisomy 21;   Trisomy 18;   Trisomy 13;   Down Syndrome
Intervention:
25 Unknown  Memantine and Down's Syndrome
Conditions: Down's Syndrome;   Dementia;   Learning Disabilities
Intervention: Drug: Memantine Hydrochloride
26 Recruiting Prenatal Screening for Down Syndrome With DNAFirst
Conditions: Trisomy 21;   Trisomy 18;   Trisomy 13;   Monosomy X
Intervention:
27 Unknown  Frequency of Metabolic Syndrome in Down Syndrome Patients
Conditions: Metabolic Syndrome X;   Down Syndrome
Intervention:
28 Recruiting Non Invasive Prenatal Diagnosis of Trisomy 21 by Genetic Analysis of Circulating Fetal Cells
Condition: Trisomy 21
Intervention: Other: sample blood
29 Recruiting Specimen Collection From Pregnant Women at Increased Risk for Fetal Aneuploidy
Conditions: Down Syndrome;   Fetal Aneuploidy
Intervention:
30 Recruiting Clinical Evaluation of the SEQureDx T21 Test In High Risk Pregnancies
Conditions: Down Syndrome;   Fetal Aneuploidy
Intervention:
31 Unknown  Non-Invasive Determination of Fetal Chromosome Abnormalities
Conditions: Down Syndrome (Trisomy 21);   Edward's Syndrome (Trisomy 18);   Patau Syndrome (Trisomy 13);   Klinefelter Syndrome (47, XXY);   and Other Chromosome;   Abnormalities.
Intervention:
32 Recruiting Noninvasive Screening for Affected Pregnancies: Assay Development & Optimization in Affected Pregnancies
Conditions: Down Syndrome;   Aneuploidy
Intervention: Other: Maternal blood draw of 30 to 50ml
33 Not yet recruiting Use of eHealth in Communication With Patients About Prenatal Diagnosis
Conditions: Downs Syndrome;   Health Knowledge, Attitudes, Practice
Interventions: Behavioral: Access to the website www.graviditetsportalen.dk;   Behavioral: Access to the website www.ouh.dk
34 Recruiting Normalization of dyrk1A and APP Function as an Approach to Improve Cognitive Performance and Decelerate AD Progression in DS Subjects: Epigallocatechin Gallate as Therapeutic Tool
Condition: Down Syndrome (DS)
Intervention: Dietary Supplement: Epigallocatechin-3-gallate (EGCG)
35 Recruiting Development of Non-invasive Prenatal Test for Microdeletion/Duplication and Other Genetic Syndromes Based on Fetal DNA Isolated From Maternal Blood
Conditions: Microdeletion Syndromes;   Trisomy 21;   Trisomy 18;   Trisomy 13;   Sex Chromosome Abnormalities
Intervention:
36 Recruiting Prenatal Non-invasive Aneuploidy Test Utilizing SNPs Trial
Conditions: Trisomy 13;   Trisomy 18;   Trisomy 21;   Aneuploidy
Intervention: Procedure: Blood Draw
37 Not yet recruiting DIR/ Floortime™ Parent Training Intervention for the Children With Developmental Disabilities
Conditions: Cerebral Palsy;   Down's Syndrome;   Delayed Development
Interventions: Behavioral: Parent training;   Behavioral: Routine care
38 Recruiting Study of Blood Samples From Newborns With Down Syndrome
Condition: Leukemia
Interventions: Genetic: DNA analysis;   Genetic: RNA analysis;   Genetic: cytogenetic analysis;   Genetic: fluorescence in situ hybridization;   Genetic: gene expression analysis;   Genetic: microarray analysis;   Genetic: mutation analysis;   Genetic: polymerase chain reaction;   Genetic: polymorphism analysis;   Other: flow cytometry;   Other: laboratory biomarker analysis;   Other: pharmacological study
39 Recruiting Development of Non-invasive Prenatal Screening Test for Microdeletions Based on Fetal DNA Isolated From Maternal Blood
Conditions: Trisomy 21;   Trisomy 18;   Trisomy 13;   Sex Chromosome Abnormalities;   Microdeletion Syndromes
Intervention:
40 Recruiting Study of the Efficacy of New Non-invasive Prenatal Tests for Screening for Fetal Trisomies Using Maternal Blood
Conditions: Trisomy 21;   Trisomy 18;   Trisomy 13
Interventions: Other: Integrated prenatal screening for Down's syndrome;   Other: Serum QUAD Assay for aneuploidy screening;   Other: Targeted NIPT assay using ccfDNA in maternal blood;   Other: Un-targeted NIPT assay using ccfDNA in maternal blood;   Other: Harmony™ Test (Ariosa Diagnostics)

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Indicates status has not been verified in more than two years