49 studies found for:    Open Studies | "Down Syndrome"
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Rank Status Study
21 Unknown  Glucose Metabolic, Amyloid, and Tau Brain Imaging in Down Syndrome and Dementia
Conditions: Down Syndrome;   Alzheimer's Disease
Intervention:
22 Recruiting Non Invasive Prenatal Diagnosis of Trisomy 21 by Genetic Analysis of Circulating Fetal Cells
Condition: Trisomy 21
Intervention: Other: sample blood
23 Recruiting A Study of RG1662 in Adults and Adolescents With Down Syndrome (CLEMATIS)
Condition: Down Syndrome
Interventions: Drug: Placebo;   Drug: RG1662
24 Recruiting A 4-Week Safety Study of Oral ELND005 in Young Adults With Down Syndrome Without Dementia
Condition: Down Syndrome
Interventions: Drug: ELND005;   Drug: Placebo
25 Recruiting Assessment of Bone Density and Bone Turnover Markers in Patients With Down Syndrome and Comparison to the Ts65Dn Model
Condition: Down Syndrome
Intervention: Genetic: Skeletal Status Assessment of a Down Syndrome Population
26 Recruiting A Screening Protocol to Assess Adults and Adolescents With Down Syndrome for Eligibility For Upcoming Study of RG1662 (Study BP27832)
Condition: Down Syndrome
Intervention:
27 Unknown  Frequency of Metabolic Syndrome in Down Syndrome Patients
Conditions: Metabolic Syndrome X;   Down Syndrome
Intervention:
28 Recruiting Specimen Collection From Pregnant Women at Increased Risk for Fetal Aneuploidy
Conditions: Down Syndrome;   Fetal Aneuploidy
Intervention:
29 Recruiting Clinical Evaluation of the SEQureDx T21 Test In High Risk Pregnancies
Conditions: Down Syndrome;   Fetal Aneuploidy
Intervention:
30 Recruiting Non-Invasive Chromosomal Evaluation of Trisomy Study
Conditions: Fetal Aneuploidy;   Trisomy 21;   Trisomy 18;   Trisomy 13;   Down Syndrome
Intervention:
31 Not yet recruiting Use of eHealth in Communication With Patients About Prenatal Diagnosis
Conditions: Downs Syndrome;   Health Knowledge, Attitudes, Practice
Interventions: Behavioral: Access to the website www.graviditetsportalen.dk;   Behavioral: Access to the website www.ouh.dk
32 Recruiting Noninvasive Screening for Affected Pregnancies: Assay Development & Optimization in Affected Pregnancies
Conditions: Down Syndrome;   Aneuploidy
Intervention: Other: Maternal blood draw of 30 to 50ml
33 Recruiting Prenatal Non-invasive Aneuploidy Test Utilizing SNPs Trial
Conditions: Trisomy 13;   Trisomy 18;   Trisomy 21;   Aneuploidy
Intervention: Procedure: Blood Draw
34 Recruiting Development of Non-invasive Prenatal Test for Microdeletion/Duplication and Other Genetic Syndromes Based on Fetal DNA Isolated From Maternal Blood
Conditions: Microdeletion Syndromes;   Trisomy 21;   Trisomy 18;   Trisomy 13;   Sex Chromosome Abnormalities
Intervention:
35 Not yet recruiting The Effect of Bifocals in Children With Down Syndrome
Conditions: Visual Acuity at Near;   Accuracy of Accommodation;   Prevention of Strabismus;   Task Readiness
Interventions: Device: bifocals;   Device: single vision glasses
36 Recruiting Clinical Performance of the MaterniT21 PLUS LDT in Multiple Gestation Pregnancies
Conditions: Down Syndrome;   Edwards Syndrome;   Patau Syndrome;   Turner Syndrome
Intervention:
37 Not yet recruiting DIR/ Floortime™ Parent Training Intervention for the Children With Developmental Disabilities
Conditions: Cerebral Palsy;   Down's Syndrome;   Delayed Development
Interventions: Behavioral: Parent training;   Behavioral: Routine care
38 Recruiting Normalization of dyrk1A and APP Function as an Approach to Improve Cognitive Performance and Decelerate AD Progression in DS Subjects: Epigallocatechin Gallate as Therapeutic Tool
Condition: Down Syndrome (DS)
Intervention: Dietary Supplement: Epigallocatechin-3-gallate (EGCG)
39 Unknown  Non-Invasive Determination of Fetal Chromosome Abnormalities
Conditions: Down Syndrome (Trisomy 21);   Edward's Syndrome (Trisomy 18);   Patau Syndrome (Trisomy 13);   Klinefelter Syndrome (47, XXY);   and Other Chromosome;   Abnormalities.
Intervention:
40 Recruiting Study of Blood Samples From Newborns With Down Syndrome
Condition: Leukemia
Interventions: Genetic: DNA analysis;   Genetic: RNA analysis;   Genetic: cytogenetic analysis;   Genetic: fluorescence in situ hybridization;   Genetic: gene expression analysis;   Genetic: microarray analysis;   Genetic: mutation analysis;   Genetic: polymerase chain reaction;   Genetic: polymorphism analysis;   Other: flow cytometry;   Other: laboratory biomarker analysis;   Other: pharmacological study

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Indicates status has not been verified in more than two years