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40 studies found for:    Open Studies | "Down Syndrome"

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Rank Status Study
1 Recruiting Down Syndrome Metabolic Health Study
Conditions: Down Syndrome;   Trisomy 21
Intervention:
2 Recruiting Nicotine Treatment of Cognitive Decline in Down Syndrome
Conditions: Down Syndrome;   Mild Cognitive Impairment
Interventions: Drug: Low Dose Nicotine (5mg);   Drug: Moderate Dose Nicotine (10mg)
3 Recruiting Treatment Trial of Subclinical Hypothyroidism in Down Syndrome
Conditions: Down Syndrome;   Subclinical Hypothyroidism
Intervention: Drug: Levothyroxine
4 Recruiting History of Amyloid Deposition in Adults With Down Syndrome
Conditions: Down Syndrome;   Amyloid Deposition;   Alzheimers Disease
Intervention:
5 Recruiting Obstructive Sleep Apnea and Neurocognitive and Cardiovascular Function in Children With Down Syndrome
Conditions: Down Syndrome;   Obstructive Sleep Apnea Syndrome
Interventions: Device: Continuous positive airway pressure;   Device: Sham or placebo continuous positive airway pressure
6 Recruiting Rivastigmine Study in Adolescents With Down Syndrome
Condition: Down Syndrome
Interventions: Drug: Rivastigmine;   Other: Liquid Placebo
7 Recruiting Evaluation of a Simplified Method for Diagnosis of Sleep Apnea in Children and Adults With Down Syndrome
Condition: Down Syndrome
Intervention: Other: Polysomnography
8 Unknown † Trends in Intellectual Development in Down Syndrome
Condition: Down Syndrome
Intervention:
9 Recruiting Down Syndrome and Continuous Positive Pressure Therapy
Conditions: Down Syndrome;   Obstructive Sleep Apnea Syndrome
Intervention: Device: Continuous Positive Pressure
10 Recruiting Gait Parameters of Persons With Down Syndrome With and Without Orthotics Using GaitRite
Condition: Down Syndrome
Intervention: Procedure: custom orthotics
11 Recruiting Efficacy Assessment of Systematic Treatment With Folinic Acid and Thyroid Hormone on Psychomotor Development of Down Syndrome Young Children
Condition: Down Syndrome
Intervention: Drug: thyroid hormone and folinic acid
12 Unknown † Natural History of Amyloid Deposition in Adults With Down Syndrome
Condition: Down Syndrome
Intervention:
13 Not yet recruiting Intensive Dysarthria Sessions in Adults and Children With Down Syndrome
Conditions: Dysarthria;   Down Syndrome
Intervention: Behavioral: Speech sessions
14 Unknown † Amyloid Plaque and Tangle Imaging in Alzheimer's Disease and Down Syndrome
Conditions: Down Syndrome;   Alzheimer's Disease
Intervention:
15 Unknown † Neuromuscular Characteristics of Individuals With Down Syndrome (DS)
Condition: Down Syndrome
Intervention: Other: muscle strength
16 Recruiting A Study of RG1662 in Individuals With Down Syndrome
Condition: Down Syndrome
Interventions: Drug: RG1662;   Drug: Placebo
17 Not yet recruiting Trisomy 21 in Adulthood
Condition: Down Syndrome
Intervention: Genetic: karyotype
18 Recruiting Glucose Metabolic, Amyloid, and Tau Brain Imaging in Down Syndrome and Dementia
Conditions: Down Syndrome;   Alzheimer's Disease
Intervention:
19 Unknown † Memantine and Down's Syndrome
Conditions: Down's Syndrome;   Dementia;   Learning Disabilities
Intervention: Drug: Memantine Hydrochloride
20 Recruiting A Molecular and Functional Brain Imaging Study in Individuals With Down Syndrome and Healthy Controls Following Single Dose RG1662
Condition: Down Syndrome, Healthy Volunteer
Interventions: Drug: RG1662;   Drug: placebo
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† Indicates status has not been verified in more than two years