69 studies found for:    Open Studies | "Cholangiocarcinoma"
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21 Recruiting CPI-613 in Treating Patients With Advanced or Metastatic Bile Duct Cancer That Cannot Be Removed By Surgery
Conditions: Adult Primary Cholangiocellular Carcinoma;   Advanced Adult Primary Liver Cancer;   Cholangiocarcinoma of the Extrahepatic Bile Duct;   Cholangiocarcinoma of the Gallbladder;   Localized Unresectable Adult Primary Liver Cancer;   Metastatic Extrahepatic Bile Duct Cancer;   Recurrent Adult Primary Liver Cancer;   Recurrent Extrahepatic Bile Duct Cancer;   Unresectable Extrahepatic Bile Duct Cancer
Intervention: Drug: 6,8-bis(benzylthio)octanoic acid
22 Recruiting Trametinib or Combination Chemotherapy in Treating Patients With Refractory or Advanced Biliary or Gallbladder Cancer or That Cannot Be Removed By Surgery
Conditions: Adult Primary Cholangiocellular Carcinoma;   Advanced Adult Primary Liver Cancer;   Cholangiocarcinoma of the Extrahepatic Bile Duct;   Cholangiocarcinoma of the Gallbladder;   Localized Unresectable Adult Primary Liver Cancer;   Metastatic Extrahepatic Bile Duct Cancer;   Recurrent Adult Primary Liver Cancer;   Recurrent Childhood Liver Cancer;   Recurrent Extrahepatic Bile Duct Cancer;   Recurrent Gallbladder Cancer;   Stage C Adult Primary Liver Cancer (BCLC);   Stage D Adult Primary Liver Cancer (BCLC);   Stage II Gallbladder Cancer;   Stage III Childhood Liver Cancer;   Stage IIIA Gallbladder Cancer;   Stage IIIB Gallbladder Cancer;   Stage IV Childhood Liver Cancer;   Stage IVA Gallbladder Cancer;   Stage IVB Gallbladder Cancer;   Unresectable Extrahepatic Bile Duct Cancer
Interventions: Drug: trametinib;   Drug: leucovorin calcium;   Drug: fluorouracil;   Drug: capecitabine;   Other: laboratory biomarker analysis
23 Recruiting Genotype-guided Dosing of mFOLFIRINOX Chemotherapy in Patients With Previously Untreated Advanced Gastrointestinal Malignancies
Conditions: Acinar Cell Adenocarcinoma of the Pancreas;   Adenocarcinoma of the Gallbladder;   Adenocarcinoma of Unknown Primary;   Adult Primary Cholangiocellular Carcinoma;   Advanced Adult Primary Liver Cancer;   Cholangiocarcinoma of the Extrahepatic Bile Duct;   Cholangiocarcinoma of the Gallbladder;   Diffuse Adenocarcinoma of the Stomach;   Duct Cell Adenocarcinoma of the Pancreas;   Intestinal Adenocarcinoma of the Stomach;   Localized Unresectable Adult Primary Liver Cancer;   Metastatic Carcinoma of Unknown Primary;   Metastatic Extrahepatic Bile Duct Cancer;   Mixed Adenocarcinoma of the Stomach;   Mucinous Adenocarcinoma of the Colon;   Mucinous Adenocarcinoma of the Rectum;   Newly Diagnosed Carcinoma of Unknown Primary;   Signet Ring Adenocarcinoma of the Colon;   Signet Ring Adenocarcinoma of the Rectum;   Stage III Pancreatic Cancer;   Stage IIIA Colon Cancer;   Stage IIIA Gallbladder Cancer;   Stage IIIA Gastric Cancer;   Stage IIIA Rectal Cancer;   Stage IIIB Colon Cancer;   Stage IIIB Gallbladder Cancer;   Stage IIIB Gastric Cancer;   Stage IIIB Rectal Cancer;   Stage IIIC Colon Cancer;   Stage IIIC Gastric Cancer;   Stage IIIC Rectal Cancer;   Stage IV Gastric Cancer;   Stage IV Pancreatic Cancer;   Stage IVA Colon Cancer;   Stage IVA Gallbladder Cancer;   Stage IVA Rectal Cancer;   Stage IVB Colon Cancer;   Stage IVB Gallbladder Cancer;   Stage IVB Rectal Cancer;   Unresectable Extrahepatic Bile Duct Cancer
Interventions: Drug: oxaliplatin;   Drug: irinotecan hydrochloride;   Drug: leucovorin calcium;   Drug: fluorouracil;   Other: laboratory biomarker analysis
24 Recruiting A Phase I/II Study Safety and Efficacy Study of PCI of Gemcitabine and Chemotherapy in Patients With Cholangiocarcinomas
Condition: Cholangiocarcinoma
Interventions: Drug: Amphinex and Gemcitabine;   Drug: Gemcitabine and Cisplatin
25 Recruiting Optimization of Health Expenditure in Liver Surgery
Conditions: Hepatocellular Carcinoma;   Hilar Cholangiocarcinoma;   Intra Hepatic Cholangiocarcinoma;   Liver Metastasis
Intervention: Procedure: liver surgery
26 Recruiting Hepatic Arterial Infusion in Treating Patients With Locally Advanced, Non-Metastatic Cholangiocarcinoma
Conditions: Cholangiocarcinoma;   Liver Neoplasms
Interventions: Drug: Floxuridine;   Drug: Dexamethasone;   Drug: Gemcitabine;   Drug: Oxaliplatin
27 Recruiting Study Of Intrahepatic Arterial Injection of 90-Y Glass Microspheres for Cholangiocarcinoma
Condition: Cholangiocarcinoma
Intervention: Device: TheraSphere® Yttrium-90 (Y-90) Microspheres
28 Recruiting Phase 1 Study of Pazopanib With GSK1120212 in Advanced Solid Tumors, Enriched With Patients With Differentiated Thyroid Cancer, Soft-tissue Sarcoma, and Cholangiocarcinoma
Conditions: Solid Tumors;   Thyroid Cancer;   Soft-tissue Sarcoma;   Cholangiocarcinoma
Interventions: Drug: Pazopanib;   Drug: GSK1120212
29 Recruiting A Study of Gemcitabine as an Adjuvant Treatment for Cholangiocarcinoma After Surgical Resection
Condition: Cholangiocarcinoma
Intervention: Drug: Gemcitabine
30 Recruiting Stereotactic Body Radiotherapy for Hepatocellular Carcinoma, and Intrahepatic Cholangiocarcinoma
Conditions: Carcinoma, Hepatocellular;   Intrahepatic Cholangiocarcinoma
Intervention: Radiation: Stereotactic radiation
31 Recruiting Drug-Eluting Bead, Irinotecan Therapy for Unresectable Intrahepatic Cholangiocarcinoma w/Concomitant Gemcitabine and Cisplatin
Condition: Unresectable Intrahepatic Cholangiocarcinoma
Interventions: Device: LC Bead with Gem-Cis;   Drug: Gemcitabine and Cisplatin
32 Recruiting IRS(Irradiation Stent) vs. CS(Conventional Stent) Insertion in Inoperable Malignant Biliary Obstruction
Condition: Cholangiocarcinoma
Interventions: Procedure: Stenting;   Device: self-expandable metallic biliary stent loaded with 125 iodine seeds;   Device: conventional biliary self-expandable stent;   Procedure: brachytherapy
33 Recruiting Endobiliary RFA for Unresectable Malignant Biliary Strictures
Conditions: Cholangiocarcinoma;   Ampullary Carcinoma
Intervention: Procedure: Radiofrequency ablation (RFA)
34 Recruiting Pilot Study of Irreversible Electroporation (IRE) to Treat Metastatic Liver Cancer & Cholangiocarcinoma
Conditions: Metastatic Liver Cancer;   Cholangiocarcinoma;   Neoplasm Metastasis
Intervention: Procedure: Irreversible electroporation (IRE)
35 Recruiting ADH-1, Gemcitabine Hydrochloride and Cisplatin in Treating Patients With Metastatic Pancreatic or Biliary Tract Cancer That Cannot Be Removed By Surgery
Conditions: Acinar Cell Adenocarcinoma of the Pancreas;   Adenocarcinoma of the Gallbladder;   Adult Primary Cholangiocellular Carcinoma;   Advanced Adult Primary Liver Cancer;   Cholangiocarcinoma of the Gallbladder;   Duct Cell Adenocarcinoma of the Pancreas;   Localized Unresectable Adult Primary Liver Cancer;   Periampullary Adenocarcinoma;   Recurrent Adult Primary Liver Cancer;   Recurrent Gallbladder Cancer;   Recurrent Pancreatic Cancer;   Stage II Gallbladder Cancer;   Stage III Pancreatic Cancer;   Stage IIIA Gallbladder Cancer;   Stage IIIB Gallbladder Cancer;   Stage IV Pancreatic Cancer;   Stage IVA Gallbladder Cancer;   Stage IVB Gallbladder Cancer
Interventions: Drug: ADH-1;   Drug: cisplatin;   Drug: gemcitabine hydrochloride;   Other: laboratory biomarker analysis
36 Recruiting Liver Transplantation for Hilar Cholangiocarcinoma in Association With Neoadjuvant Radio- and Chemo-therapy
Conditions: Hilar Cholangiocarcinoma;   Primary Sclerosing Cholangitis
Interventions: Procedure: Liver transplantation;   Radiation: 45 Gy external radiations;   Radiation: Endoluminal bile duct Brachytherapy;   Drug: Capecitabine;   Procedure: Pre liver transplantation laparoscopic hand assisted staging
37 Recruiting Selective Internal Radiotherapy (SIRT) Versus Transarterial Chemoembolisation (TACE) for the Treatment of Cholangiocellular Carcinoma (CCC).
Condition: Intrahepatic Cholangiocellular Carcinoma
Interventions: Procedure: DEB TACE;   Procedure: SIRT
38 Recruiting Downsizing of Unresectable Cholangiocarcinoma by Combined Intravenous and Intra-arterial Chemotherapy
Condition: Cholangiocellular Carcinoma
Intervention: Drug: Selective intra-arterial floxuridine and systemic gemcitabine and cisplatin
39 Recruiting Adjuvant Cisplatin Plus Gemcitabine in Operable Cholangiocellular Carcinoma.
Condition: Cholangiocellular Carcinoma
Intervention: Drug: Cisplatin and Gemcitabine
40 Recruiting Endoscopic Bipolar Radiofrequency Probe (ENDOHPB) in the Management of Unresectable Bile Duct and Pancreatic Cancer
Conditions: Cholangiocarcinoma;   Pancreatic Cancer
Intervention: Device: Endoscopic bipolar radiofrequency probe (ENDOHPB)

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