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681 studies found for:    Open Studies | "Bone Marrow Diseases"

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1 Recruiting A Double-Blind, Placebo Controlled Study of Intravenous Immunoglobulin for HIV-Associated Myelopathy
Condition: HIV-associated Myelopathy
Interventions: Drug: Intravenous Immunoglobulin;   Drug: Placebo
2 Recruiting Anterior Vs Posterior Procedures for Cervical Spondylotic Myelopathy: Prospective Randomized Clinical Trial
Condition: Cervical Spondylotic Myelopathy
Interventions: Procedure: ACDF;   Procedure: Cervical laminoplasty
3 Recruiting Safety Study of Preservon-Treated Bone Implants for Cervical Fusion in the Treatment of Cervical Radiculopathy or Myelopathy
Conditions: Cervical Radiculopathy;   Myelopathy
Intervention: Procedure: Anterior Cervical Discectomy and Fusion
4 Recruiting CNS Growth Factors Release and Changes in the Inflammatory Environment in Response to Electrical Stimulation in Subjects With Inflammatory Myelopathies
Condition: Inflammatory Myelopathies
Interventions: Device: FES Cycling;   Device: Cycling without FES;   Procedure: Lumbar puncture;   Behavioral: Mood assessment
5 Recruiting Efficacy of Riluzole in Surgical Treatment for Cervical Spondylotic Myelopathy (CSM-Protect)
Condition: Cervical Spondylotic Myelopathy
Interventions: Drug: riluzole;   Drug: Placebo medication
6 Recruiting A Phase II Clinical Trial on Comparison of Effectiveness and Safeness of Different Amifostine Regimens
Conditions: Nasopharyngeal Neoplasms;   Salivary Gland Diseases;   Bone Marrow Diseases;   Mucositis
Interventions: Drug: Amifostine every-other-day regimen;   Drug: Amifostine everyday regimen
7 Recruiting A Phase Ib/II Dose-finding Study to Assess the Safety and Efficacy of LDE225 + INC424 in Patients With MF
Conditions: Primary Myelofibrosis;   Thrombocythemia, Essential;   Thrombocytosis;   Myeloproliferative Disorders;   Bone Marrow Diseases;   Hematologic Diseases;   Blood Coagulation Disorders;   Blood Platelet Disorders;   Hemorrhagic Disorders
Interventions: Drug: LDE225;   Drug: INC424
8 Recruiting Clofarabine Followed By Lenalidomide for High-Risk Myelodysplastic Syndromes and Acute Myeloid Leukemia
Conditions: Myeldysplastic Syndrome (MDS);   Chronic Myelomonocytic Leukemia;   Bone Marrow Diseases;   Neutropenia;   Acute Myeloid Leukemia (AML)
Interventions: Drug: Clofarabine;   Drug: Lenalidomide
9 Recruiting Radotinib Versus Imatinib in Newly Diagnosed Philadelphia Chromosome and Chronic Myeloid Leukemia Chronic Phase Patients
Conditions: Leukemia;   Leukemia, Myeloid;   Leukemia, Myelogenous, Chronic, BCR-ABL Positive;   Philadelphia Chromosome;   Bone Marrow Diseases;   Hematologic Diseases
Interventions: Drug: Imatinib;   Drug: Radotinib
10 Recruiting Interbody Fusion Devices in the Treatment of Cervicobrachial Syndrome
Conditions: Radiating Pain;   Myelopathy;   Cervicobrachial Syndrome
Interventions: Device: Anterior cervical discectomy and fusion (ACDF) with PEEK Cage;   Device: Anterior cervical discectomy and fusion (ACDF) with a Valeo CSC Cage
11 Not yet recruiting Open Label, Phase II Study to Evaluate Efficacy and Safety of Oral Nilotinib in Philadelphia Positive (Ph+) Chronic Myelogenous Leukemia (CML) Pediatric Patients.
Conditions: Leukemia;   Leukemia,Pediatric;   Leukemia, Myleiod;   Leukemia, Mylegenous, Chronic;   Leukemia, Mylegenous, Accelerated;   BCR-ABL Positive;   Myeloproliferative Disorder;   Bone Marrow Disease;   Hematologic Diseases;   Neoplastic Processes;   Imatinib;   Dasatinib;   Enzyme Inhibitor;   Protein Kinase Inhibitor
Intervention: Drug: nilotinib
12 Unknown † Reorganization of Brain Functions in Patients With Cervical Myelopathy Using fMRI and MRS
Condition: Spinal Cord Diseases
Interventions: Procedure: Decompressive cervical spine surgery;   Procedure: fMRI and MRS scan
13 Recruiting Hu Mik-Beta-1 to Treat HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis
Condition: HTLV-1
Intervention: Drug: Hu MiK-Beta-1
14 Recruiting Campath/Fludarabine/Melphalan Transplant Conditioning for Non-Malignant Diseases
Conditions: Metabolic Disorders;   Hematologic, Immune, or Bone Marrow Disorders;   Hemoglobinopathies
Interventions: Drug: Transplant conditioning regimen of alemtuzumab, fludarabine, and melphalan;   Drug: Transplant conditioning regimen of hydroxyurea, campath, fludarabine, thiotepa, & melphalan
15 Recruiting Arthroplasty Versus Fusion in Anterior Cervical Surgery: Prospective Study of the Impact on the Adjacent Level
Conditions: Clinical Radiculopathy;   Myelopathy Due to a Cervical Disk Disease
Interventions: Device: cervical disc prosthesis with a mobile insert named Mobi-C;   Procedure: arthrodesis - cervical disk surgery
16 Unknown † Anesthesia Induction in Patients Undergoing Surgery for Cervical Myelopathy
Condition: Spinal Cord Diseases
Intervention: Drug: anaesthetics: sevofluorane
17 Recruiting Denosumab Compared to Zoledronic Acid in the Treatment of Bone Disease in Subjects With Multiple Myeloma
Conditions: Cancer;   Hematologic Malignancies;   Multiple Myeloma;   Oncology;   Bone Metastases;   Multiple Myeloma Bone Lesions
Interventions: Drug: Denosumab;   Drug: Zoledronic acid
18 Unknown † Bortezomib and Low Dose Cytarabine in the Treatment of High-Risk Myelodysplastic Syndromes
Condition: Myelodysplastic Syndromes
Intervention: Drug: Bortezomib
19 Recruiting Ponatinib in Newly Diagnosed Chronic Myeloid Leukemia (CML) (EPIC)
Condition: Chronic Myeloid Leukemia
Interventions: Drug: ponatinib;   Drug: imatinib (Gleevec/ Glivec)
20 Available Expanded Access Protocol (EAP) Using the CliniMACS® Device for Pediatric Haplocompatible Donor Stem Cell Transplant
Conditions: Acute Lymphoblastic Leukemia;   Acute Myeloid Leukemia;   Chronic Myeloid Leukemia;   Myelodysplastic Syndrome;   Lymphomas;   Bone Marrow Failure;   Hemoglobinopathy;   Immune Deficiency;   Osteopetrosis;   Cytopenias;   White Blood Cell Abnormalities;   Red Blood Cell Abnormalities
Intervention: Biological: CD34+ enriched, T Cell Depleted donor stem cell product
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† Indicates status has not been verified in more than two years