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127 studies found for:    Open Studies | "Anemia, Sickle Cell"

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Open Studies | "Anemia, Sickle Cell"
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Rank Status Study
1 Recruiting Carbon Monoxide Levels and Sickle Cell Disease Severity
Conditions: Sickle Cell Disease;   Sickle Cell Anemia;   Anemia, Sickle Cell
Intervention:
2 Recruiting Effects of HQK-1001 in Patients With Sickle Cell Disease
Conditions: Sickle Cell Disease;   Sickle Cell Anemia;   Sickle Cell Disorders;   Hemoglobin S Disease;   Sickling Disorder Due to Hemoglobin S
Interventions: Drug: HQK-1001;   Drug: Placebo
3 Recruiting Microvascular Blood Flow in Sickle Cell Anemia
Conditions: Sickle Cell Disease;   Sickle Cell Anemia
Interventions: Drug: regadenoson infusion with contrast-enhanced ultrasound;   Procedure: contrast-enhanced ultrasound
4 Not yet recruiting A Pilot Study of N-acetylcysteine in Patients With Sickle Cell Disease
Conditions: Sickle Cell Disease;   Sickle Cell Anemia
Intervention: Drug: N-Acetylcysteine
5 Unknown † A Randomized Trial of LOVAZA in Pediatric Sickle Cell Disease (SCD)
Conditions: Sickle Cell Disease;   HEMOGLOBIN SS;   Hemoglobin S Beta-0 Thalassemia;   Inflammation;   Quality of Life
Interventions: Dietary Supplement: Omega-3 Fatty Acids: Eicosapentaenoic Acid (EPA) and Docosahexaenoic Acid (DHA);   Other: Placebo Capsules
6 Recruiting Efficacy of Vorinostat to Induce Fetal Hemoglobin in Sickle Cell Disease
Conditions: Sickle Cell Disease;   Sickle Cell Anemia
Intervention: Drug: vorinostat
7 Unknown † Clinical Importance of Treating Iron Overload in Sickle Cell Disease
Conditions: Anemia, Sickle Cell;   Transfusion Hemochromatosis
Intervention: Drug: deferasirox
8 Unknown † Effectiveness of a Computerized Tool (PAINRelieveIt) to Help Manage Pain Related to Sickle Cell Disease
Conditions: Anemia, Sickle Cell;   Hemoglobin SC Disease
Interventions: Behavioral: PAINReportIt;   Behavioral: PAINUCope;   Behavioral: PAINConsultN
9 Recruiting Nonmyeloablative Haploidentical Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Severe Congenital Anemias Including Sickle Cell Disease and Beta-Thalassemia
Conditions: Peripheral Blood Stem Cell Transplantation;   Anemia, Sickle Cell;   Graft-Versus-Host Disease;   Sirolimus (Rapamune(Registered Trademark));   Alemtuzumab (Campath(Registered Trademark))
Interventions: Procedure: PBMC Transplant;   Drug: Alemtuzumab (Campath(Registered Trademark));   Drug: Sirolimus (Rapamune(Registered Trademark));   Drug: Cyclophosphamide (Cytoxan(Registered Trademark));   Procedure: Low Dose Irradiation
10 Recruiting Antioxidant Therapy to Reduce Inflammation in Sickle Cell Disease
Condition: Anemia, Sickle Cell
Intervention: Drug: alpha-lipoic acid and acetyl-L-carnitine
11 Unknown † Arginine Treatment of Acute Chest Syndrome (Pneumonia) in Sickle Cell Disease Patients
Conditions: Anemia, Sickle Cell;   Pneumonia
Intervention: Drug: Arginine hydrochloride
12 Recruiting A Single Dose Study of the Safety, Blood Levels and Biological Effects of Aes-103 Compared to Placebo in Subjects With Stable Sickle Cell Disease
Condition: Anemia, Sickle Cell
Interventions: Drug: Aes-103;   Drug: Placebo
13 Recruiting Adolescent, Caregiver, and Young Adult Perspectives of the Transition From Pediatric to Adult Care for Sickle Cell Disease: A Preliminary Evaluation of the Sickle Cell Disease Transition Program
Condition: Sickle Cell Disease
Intervention: Other: Assessment
14 Unknown † MACS Study - Microparticles and Coagulation in Sickle Cell Disease
Condition: Sickle Cell Disease
Intervention:
15 Recruiting Cognitive Rehabilitation in Sickle Cell Disease
Conditions: Sickle Cell Disease;   Cognitive Impairment
Intervention: Behavioral: Cogmed
16 Recruiting N-Acetylcysteine in Patients With Sickle Cell Disease
Condition: Sickle Cell Disease
Interventions: Drug: N-Acetylcysteine;   Drug: Placebo
17 Recruiting Iron Mediated Vascular Disease in Sickle Cell Anemia Patients
Condition: Sickle Cell Disease
Intervention:
18 Recruiting Topical Sodium Nitrite for Chronic Leg Ulcers in Adult Patients With Blood Disorders
Conditions: Sickle Cell Anemia;   Sickle Cell Disease;   Chronic Hemolytic Disorders
Intervention: Drug: Sodium Nitrite Cream
19 Recruiting Evaluating the Safety and Effectiveness of Bone Marrow Transplants in Children With Sickle Cell Disease (BMT CTN #0601) (The SCURT Study)
Condition: Sickle Cell Disease
Intervention: Biological: Hematopoietic Stem Cell Transplantation
20 Recruiting Cardiovascular Complications of Sickle Cell Disease
Condition: Sickle Cell Disease
Intervention: Procedure: MRI, Transthoracic Echocardiography, tonometry, EKG
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† Indicates status has not been verified in more than two years