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72 studies found for:    Open Studies | "Amyotrophic Lateral Sclerosis"

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Rank Status Study
1 Recruiting Phase II/III Randomized, Placebo-controlled Trial of Arimoclomol in SOD1 Positive Familial Amyotrophic Lateral Sclerosis
Conditions: Amyotrophic Lateral Sclerosis 1;   Acquired Amyotrophic Lateral Sclerosis;   Amyotrophic Lateral Sclerosis
Intervention: Drug: Arimoclomol
2 Recruiting Genetics of ALS: Identification of Genes With Roles in Familial and Sporadic Amyotrophic Lateral Sclerosis (ALS) and Amyotrophic Lateral Sclerosis (ALS) With Frontotemporal Dementia
Conditions: Amyotrophic Lateral Sclerosis;   Familial Amyotrophic Lateral Sclerosis;   Amyotrophic Lateral Sclerosis With Frontotemporal Dementia;   Lou Gehrig's Disease;   Motor Neuron Disease;   Primary Lateral Sclerosis
Intervention: Other: Genetic study of ALS families
3 Recruiting The National Amyotrophic Lateral Sclerosis Registry
Condition: Amyotrophic Lateral Sclerosis
Intervention:
4 Unknown † Non-Invasive Ventilation in Amyotrophic Lateral Sclerosis
Conditions: Amyotrophic Lateral Sclerosis;   Chronic Respiratory Failure
Interventions: Device: Non invasive ventilation delivered with one of the ventilator specifically designed for NIV and given to the patient by the home care providers;   Device: Non invasive ventilation
5 Recruiting Study of Ozanezumab (GSK1223249) Versus Placebo in the Treatment of Amyotrophic Lateral Sclerosis
Condition: Amyotrophic Lateral Sclerosis
Interventions: Drug: Ozanezumab;   Drug: Placebo
6 Recruiting Study of Cognitive and Emotional Disorders in Amyotrophic Lateral Sclerosis
Condition: Amyotrophic Lateral Sclerosis
Intervention: Other: MRI + 18FDG-PET + neuropsychological assessments ; 18FDG performed especially for the research
7 Recruiting Aerobic Exercise Training in Amyotrophic Lateral Sclerosis
Condition: Amyotrophic Lateral Sclerosis
Interventions: Other: Aerobic exercise training;   Other: Standard physical therapy (Stretching/Range-of-motion)
8 Recruiting Influence of the Vitamin D Blood Levels on the Amyotrophic Lateral Sclerosis Phenotype
Condition: Amyotrophic Lateral Sclerosis
Intervention: Procedure: Blood test
9 Recruiting Early Stage Amyotrophic Lateral Sclerosis Phrenic Stimulation
Conditions: Amyotrophic Lateral Sclerosis;   Respiratory Insufficiency
Interventions: Device: phenique nerve stimulation NeurX™ (Synapse Biomedical);   Device: sham phrenic nerve stimulation
10 Recruiting Safety Study of HLA-haplo Matched Allogenic Bone Marrow Derived Stem Cell Treatment in Amyotrophic Lateral Sclerosis
Conditions: Amyotrophic Lateral Sclerosis;   Motor Neuron Disease;   Neuromuscular Disease;   Neurodegenerative Disease;   Central Nervous System Disease
Intervention: Genetic: HYNR-CS-Allo
11 Recruiting Toxin Treatment for Amyotrophic Lateral Sclerosis (ALS) Related Sialorrhea
Conditions: Sialorrhea;   Amyotrophic Lateral Sclerosis
Interventions: Drug: Botox injection;   Drug: Placebo injection
12 Unknown † Cistanche Total Glycosides for Amyotrophic Lateral Sclerosis: A Randomized Control Trial (RCT) Study Assessing Clinical Response
Condition: Amyotrophic Lateral Sclerosis
Intervention: Drug: Cistanche Total Glycosides
13 Recruiting Clinical Trial on The Use of Autologous Bone Marrow Stem Cells in Amyotrophic Lateral Sclerosis (Extension CMN/ELA)
Condition: Amyotrophic Lateral Sclerosis
Interventions: Procedure: Laminectomy and bone marrow stem cells transplantation;   Procedure: Intrathecal infusion of autologous bone marrow stem cells;   Procedure: Intrathecal infusion of placebo (saline solution).
14 Recruiting Autologous Cultured Mesenchymal Bone Marrow Stromal Cells Secreting Neurotrophic Factors (MSC-NTF), in Patients With Amyotrophic Lateral Sclerosis (ALS)
Condition: Amyotrophic Lateral Sclerosis
Intervention: Biological: MSC_NTF cells transplantation by multiple intramuscular injections at 24 separate sites, in addition to a single intrathechal injection into the CSF
15 Recruiting Genetic Study of Familial and Sporadic ALS/Motor Neuron Disease, Miyoshi Myopathy and Other Neuromuscular Disorders
Conditions: Amyotrophic Lateral Sclerosis;   Frontotemporal Dementia;   PLS;   Motor Neuron Disease;   Lou Gehrigs Disease;   Familial Disease;   Amyotrophic Lateral Sclerosis, Sporadic
Intervention:
16 Recruiting Phase 3 Study of MCI-186 for Treatment of Amyotrophic Lateral Sclerosis
Condition: Amyotrophic Lateral Sclerosis (ALS)
Interventions: Drug: MCI-186;   Drug: Placebo;   Drug: MCI-186 in open label phase
17 Not yet recruiting Non-invasive Ventilation in Amyotrophic Lateral Sclerosis (ALS) Using the iVAPS Mode
Condition: Amyotrophic Lateral Sclerosis (ALS)
Intervention: Device: Non-invasive home ventilation
18 Unknown † Cortex Changes in Real/Imagined Movements in Amyotrophic Lateral Sclerosis (ALS)
Conditions: ALS;   Amyotrophic Lateral Sclerosis
Intervention:
19 Recruiting Effect of Noninvasive Ventilation on Lung Function in Amyotrophic Lateral Sclerosis
Conditions: Amyotrophic Lateral Sclerosis;   Motor Neuron Disease
Intervention: Device: noninvasive positive pressure ventilation
20 Recruiting Transcranial Direct Current Stimulation as a Novel Therapeutic Approach in Amyotrophic Lateral Sclerosis
Condition: Amyotrophic Lateral Sclerosis
Interventions: Other: transcranial direct current stimulation;   Other: Sham stimulation
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† Indicates status has not been verified in more than two years