58 studies found for:    Open Studies | "Amyloidosis"
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Open Studies | "Amyloidosis" (58 records)
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Rank Status Study
1 Recruiting A Safety Study of Carfilzomib in Patients With Previously-Treated Systemic Light Chain Amyloidosis
Conditions: Amyloidosis;   Systemic Light Chain Amyloidosis
Interventions: Drug: Carfilzomib;   Drug: Dexamethasone
2 Recruiting Prevalence of Transthyretin Amyloidosis in Hypertrophic Cardiomyopathy
Conditions: Cardiac Amyloidosis;   Amyloidosis in Transthyretin (TTR);   Hypertrophic Cardiomyopathy (HCM)
Intervention:
3 Recruiting The Effect of Diflunisal on Familial Transthyretin Amyloidosis
Condition: Amyloidosis
Intervention: Drug: Diflunisal
4 Recruiting Safety and Effect of Doxycycline in Patients With Amyloidosis
Condition: Amyloidosis
Intervention: Drug: Doxycycline
5 Recruiting Institutional Registry of Amyloidosis
Condition: Amyloidosis
Intervention:
6 Recruiting Bendamustine and Dexamethasone in Patients With Relapsed AL Amyloidosis
Condition: AL Amyloidosis
Interventions: Drug: Bendamustine;   Drug: Dexamethasone
7 Unknown  Study of Systemic Amyloidosis Presentation and Prognosis
Condition: Amyloidosis
Intervention:
8 Recruiting A Study to Evaluate the Safety of GSK2398852 When Co-administered With GSK2315698 in Patients With Systemic Amyloidosis
Condition: Amyloidosis
Interventions: Drug: GSK2398852;   Drug: GSK2315698
9 Recruiting Efficacy and Safety Study of KIACTA in Preventing Renal Function Decline in AA Amyloidosis
Condition: Amyloidosis
Interventions: Drug: KIACTA (eprodisate disodium);   Drug: Placebo
10 Recruiting Phase I, Open Label, Dose Escalation Study of NEOD001 in Subjects With Light Chain (AL) Amyloidosis
Condition: Primary Amyloidosis
Intervention: Drug: NEOD001
11 Recruiting Safety and Efficacy Study of Doxycycline/UrsoDeoxyCholicAcid on Disease Progression in ATTR Amyloidosis
Conditions: Transthyretin Amyloidosis;   Cardiomyopathy
Interventions: Drug: Doxycycline;   Drug: Ursodeoxycholic acid
12 Recruiting A Trial for Systemic Light-chain (AL) Amyloidosis
Condition: AL Amyloidosis
Intervention: Drug: BMDex
13 Unknown  Safety, Efficacy and Pharmacokinetics of Doxycycline Plus Tauroursodeoxycholic Acid in Transthyretin Amyloidosis
Condition: Transthyretin Amyloidosis
Intervention: Drug: Doxycycline + Tauroursodeoxycholic acid
14 Recruiting Transthyretin-Associated Amyloidoses Outcome Survey (THAOS)
Conditions: Transthyretin Mutations;   Transthyretin Amyloidosis
Intervention: Other: None. Observational Study.
15 Recruiting Imaging Cardiac Amyloidosis: A Pilot Study Using F-18 Florbetapir Positron Emission Tomography
Condition: Cardiac Amyloidosis
Intervention: Drug: F-18 florbetapir PET
16 Recruiting Lendexal in Patients With Primary Systemic Amyloidosis (AL) Newly Diagnosed
Condition: Primary Systemic Amyloidosis
Interventions: Drug: Lenalidomide;   Drug: Cyclophosphamide;   Drug: Dexamethasone
17 Recruiting Study of Dexamethasone Plus MLN9708 or Physician's Choice of Treatment in Relapsed or Refractory Systemic Light Chain (AL) Amyloidosis
Condition: Relapsed or Refractory Systemic Light Chain Amyloidosis
Interventions: Drug: MLN9708;   Drug: Dexamethasone;   Drug: Melphalan;   Drug: Cyclophosphamide;   Drug: Thalidomide;   Drug: Lenalidomide
18 Recruiting Tolerability and Efficacy of a Combination of Doxycycline and TUDCA in Patients With Transthyretin Amyloid Cardiomyopathy
Conditions: Amyloidosis; Heart (Manifestation);   Senile Cardiac Amyloidosis
Intervention: Drug: Tauroursodeoxycholic Acid and Doxycycline
19 Recruiting A Trial for the Treatment of Cardiac AMyloid Light-chain Amyloidosis With the Green Tea Compound Epigallocatechin-3-gallate (TAME-AL)
Conditions: Light Chain (AL) Amyloidosis;   Cardiac Involvement
Intervention: Drug: Epigallocatechin-3-gallate (EGCG)
20 Recruiting High Cut-off Hemodialysis in Patients With Advanced Cardiac AL Amyloidosis and End Stage Renal Disease
Condition: Primary Amyloidosis of Light Chain Type
Interventions: Device: High Cut-off Hemodialysis;   Drug: Chemotherapy

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