57 studies found for:    Open Studies | "Amyloidosis"
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Rank Status Study
21 Recruiting A Trial for the Treatment of Cardiac AMyloid Light-chain Amyloidosis With the Green Tea Compound Epigallocatechin-3-gallate (TAME-AL)
Conditions: Light Chain (AL) Amyloidosis;   Cardiac Involvement
Intervention: Drug: Epigallocatechin-3-gallate (EGCG)
22 Recruiting Study of Dexamethasone Plus IXAZOMIB or Physician's Choice of Treatment in Relapsed or Refractory Systemic Light Chain (AL) Amyloidosis
Condition: Relapsed or Refractory Systemic Light Chain Amyloidosis
Interventions: Drug: IXAZOMIB;   Drug: Dexamethasone;   Drug: Melphalan;   Drug: Cyclophosphamide;   Drug: Thalidomide;   Drug: Lenalidomide
23 Recruiting Body Composition in Systemic Amyloidosis
Condition: Amyloidosis
Intervention: Other: Dietary advice
24 Recruiting Ohio State University Multiple Myeloma and Amyloidosis Data Registry and Sample Resource
Conditions: Plasma Cell Dyscrasias;   Monoclonal Gammopathy of Undetermined Significance;   AL Amyloidosis;   Multiple Myeloma
Intervention: Procedure: tissue banking
25 Recruiting A Phase I/II Trial of Pomalidomide and Dexamethasone in Subjects With Previously-Treated AL Amyloidosis
Condition: AL Amyloidosis
Interventions: Drug: Pomalidomide;   Drug: Dexamthasone
26 Recruiting Bortezomib/Dexamethasone (BD), Followed By Autologous Stem Cell Transplantation and Maintenance Bortezomib/Dexamethasone For the Initial Treatment of Monoclonal Immunoglobulin Deposition Disease (MIDD) Associated With Multiple Myeloma and AL Amyloidosis
Conditions: Light Chain Deposition Disease (LCDD or MIDD);   Light Chain and Heavy Chain Deposition Disease (LHCDD or MIDD);   Monoclonal Immunoglobulin Deposition Disease (MIDD);   Amyloidosis
Intervention: Drug: Bortezomib/Dexamethasone (BD), Followed By Autologous STC & Maintenance Bortezomib/Dexamethasone
27 Recruiting Phase 2 Study to Evaluate ALN-TTRSC in Patients With Transthyretin (TTR) Cardiac Amyloidosis
Condition: TTR-mediated Amyloidosis
Intervention: Drug: ALN-TTRSC for subcutaneous administration
28 Recruiting Pomalidomide, Bortezomib, and Dexamethasone as First-Line Treatment in Treating Patients With Amyloid Light-Chain Amyloidosis or Light Chain Deposition Disease
Conditions: Light Chain Deposition Disease;   Primary Systemic Amyloidosis
Interventions: Drug: pomalidomide;   Drug: bortezomib;   Drug: dexamethasone
29 Recruiting Study of Bortezomib +HSCT in Primary Systemic Amyloidosis (AL)
Condition: Amyloidosis
Intervention: Drug: Bortezomib
30 Recruiting Tolerability and Efficacy of a Combination of Doxycycline and TUDCA in Patients With Transthyretin Amyloid Cardiomyopathy
Conditions: Amyloidosis; Heart (Manifestation);   Senile Cardiac Amyloidosis
Intervention: Drug: Tauroursodeoxycholic Acid and Doxycycline
31 Recruiting Efficacy and Safety of ISIS-TTR Rx in Familial Amyloid Polyneuropathy
Conditions: FAP;   Familial Amyloid Polyneuropathy;   TTR;   Transthyretin;   Amyloidosis
Interventions: Drug: ISIS-TTR Rx;   Drug: Placebo
32 Recruiting The Study of an Investigational Drug, ALN-TTR02, for the Treatment of Transthyretin (TTR)-Mediated Amyloidosis in Patients Who Have Already Been Treated With ALN-TTR02
Condition: TTR-mediated Amyloidosis
Intervention: Drug: ALN-TTR02 administered by intravenous (IV) infusion
33 Recruiting APOLLO: The Study of an Investigational Drug, Patisiran (ALN-TTR02), for the Treatment of Transthyretin (TTR)-Mediated Amyloidosis
Condition: TTR-mediated Amyloidosis
Interventions: Drug: patisiran (ALN-TTR02);   Drug: Sterile Normal Saline (0.9% NaCl)
34 Recruiting Safety And Efficacy Evaluation Of Fx-1006A In Subjects With Transthyretin Amyloidosis
Condition: ATTR-PN
Intervention: Drug: Tafamidis
35 Not yet recruiting Prevalence of Amyloidosis and Carpal Tunnel
Condition: Amyloid Neuropathy, Carpal Tunnel
Intervention:
36 Not yet recruiting Progression of Renal Amyloidosis of FMF and Relation to Serum SAA Level
Condition: Observational
Intervention:
37 Recruiting Pomalidomide With Melphalan and Dexamethasone for Untreated Systemic AL Amyloidosis
Condition: Myeloma
Interventions: Drug: Pomalidomide;   Drug: Melphalan;   Drug: Dexamethasone;   Behavioral: Questionnaires
38 Not yet recruiting Combined Bone Marrow and Renal Transplantation for Hematologic Disorders With End Stage Renal Disease
Conditions: Multiple Myeloma;   Bone Marrow Failure Syndromes;   Hemoglobinopathies;   AML;   ALL;   Myeloid Leukemia, Chronic;   NHL;   HL;   MDS;   Amyloidosis;   Myelofibrosis
Interventions: Drug: Tacrolimus;   Drug: Anti-thymocyte globulin;   Procedure: Kidney transplant;   Drug: Bone marrow transplant from a related donor;   Radiation: Total body irradiation 400 centigray (200 cGy X 2)
39 Recruiting Bone Marrow and Kidney Transplant for Patients With Chronic Kidney Disease and Blood Disorders
Conditions: Chronic Kidney Disease;   Acute Myeloid Leukemia (AML);   Acute Lymphoblastic Leukemia (ALL);   Chronic Myelogenous Leukemia (CML);   Chronic Lymphocytic Leukemia (CLL);   Non-Hodgkin's Lymphoma (NHL);   Hodgkin Disease;   Multiple Myeloma;   Myelodysplastic Syndrome (MDS);   Aplastic Anemia;   AL Amyloidosis;   Diamond Blackfan Anemia;   Myelofibrosis;   Myeloproliferative Disease;   Sickle Cell Anemia;   Autoimmune Diseases;   Thalassemia
Intervention: Procedure: Haploidentical Bone Marrow/Kidney
40 Recruiting A Phase 1, Single- and Multi-Dose, Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Subcutaneously Administered ALN-TTRSC in Healthy Volunteers
Condition: TTR-mediated Amyloidosis
Interventions: Drug: ALN-TTRSC;   Drug: Sterile Normal Saline (0.9% NaCl)

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Indicates status has not been verified in more than two years