69138 studies found for:    "Therapeutic Uses"
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Rank Status Study
1 Recruiting Randomized Study of Combination Chemotherapy With or Without Focused Microwave Thermotherapy Before Surgery in Treating Women With Large Breast Cancer Tumors
Condition: Breast Cancer
Interventions: Device: Focused Microwave Thermotherapy;   Drug: Chemotherapy (control)
2 Completed Safety and Efficacy of Ledipasvir/Sofosbuvir Fixed-Dose Combination (FDC) With and Without Ribavirin for the Treatment of HCV
Condition: Chronic Hepatitis C Virus
Interventions: Drug: LDV/SOF;   Drug: RBV
3 Completed Combined Treatment of Sorafenib and Pegylated Interferon α2b in Stage IV Metastatic Melanoma
Condition: Melanoma
Interventions: Drug: Sorafenib;   Drug: pegylated interferon α-2b
4 Active, not recruiting Tecemotide (L-BLP25) in Rectal Cancer
Condition: Rectal Cancer
Interventions: Other: Chemoradiation Therapy;   Drug: Cyclophosphamide (CPA);   Other: Biological: Tecemotide (L-BLP25)
5 Recruiting A Short Term Open, Randomized Cross-over Trial Exploring the Effect of Carbonic Anhydrase Inhibition by Acetazolamide on Sleep Apnea Associated Hypertension and Vascular Dysfunction
Conditions: Obstructive Sleep Apnea;   Sleep-Disordered Breathing;   Blood Pressure;   Hypertension
Interventions: Drug: Acetazolamide;   Device: nasal Continuous Positive Airway Pressure (nCPAP)
6 Recruiting Modufolin (6R 5,10-Methylenetetrahydrofolate) and Pemetrexed for Neoadjuvant Rectal Cancer Treatment
Condition: Rectal Cancer
Interventions: Drug: [6R] 5,10-methylenetetrahydrofolate;   Drug: Pemetrexed
7 Recruiting Comparing Subsartorial Saphenous Nerve Blocks With and Without Dexamethasone for Anterior Cruciate Ligament Reconstruction
Conditions: Anterior Cruciate Ligament Reconstruction;   Regional Anesthesia, Saphenous Nerve Block
Interventions: Drug: Bupivacaine Only;   Drug: Bupivacaine with 1 mg of Dexamethasone;   Drug: Bupivacaine with 4 mg of Dexamethasone
8 Active, not recruiting Compare Ceftazidime-Avibactam and Doripenem Followed by Oral Therapy for Hospitalized Adults With Complicated UTIs (Urinary Tract Infections)
Conditions: cUTI;   Complicated Urinary Tract Infection;   Acute Pyelonephritis
Interventions: Drug: CAZ-AVI;   Drug: Doripenem;   Drug: Either switch to oral therapy : 500 mg of Ciprofloxacin (oral);   Drug: or switch to oral therapy : 800 mg/160 mg of sulfamethoxazole/trimethoprim
9 Recruiting Phase I Study of a Dendritic Cell Vaccine for Patients With Either Newly Diagnosed or Recurrent Glioblastoma
Conditions: Glioblastoma;   Glioblastoma Multiforme;   Glioma;   Astrocytoma;   Brain Tumor
Interventions: Biological: Dendritic cell vaccination, in addition to standard temozolomide chemotherapy and involved field radiation therapy;   Biological: Dendritic cell vaccination, with optional bevacizumab treatment for patients previously treated with bevacizumab
10 Completed Safety and Tolerability of Repeat Courses of IM Alefacept
Condition: Chronic Plaque Psoriasis
Intervention: Drug: Alefacept
11 Recruiting Laboratory-Treated Autologous Lymphocytes, Aldesleukin, and Sargramostim (GM-CSF) in Treating Advanced Solid Tumors
Conditions: Neoplasms;   Tumors;   Solid Tumors;   Metastatic Cancer
Intervention: Biological: EGFRBi-armed autologous activated T cells
12 Completed Zonisamide for the Treatment of Obstructive Sleep Apnea in Overweight/Obese Patients
Conditions: Sleep Apnea;   Obstructive Sleep Apnea;   Obesity
Interventions: Drug: Zonisamide;   Drug: Placebo;   Device: nCPAP
13 Completed The Effect of Nebivolol on Endothelial Dysfunction in African Americans With Hypertension
Condition: High Blood Pressure
Interventions: Drug: Nebivolol;   Drug: Metoprolol succinate
14 Completed Efficacy and Safety of Budesonide Foam for Patients With Active Mild to Moderate Ulcerative Proctitis or Proctosigmoiditis
Conditions: Proctitis;   Proctosigmoiditis
Interventions: Drug: Budesonide;   Drug: Placebo
15 Recruiting Research Study of IV Vitamin C in Combination With Irinotecan vs Irinotecan Alone for Advanced Colorectal CA
Condition: Stage IV Colorectal Cancer
Intervention: Drug: Vitamin C
16 Recruiting Antiplatelet Effects of Ticagrelor Versus Clopidogrel in American Indian Patients
Condition: Coronary Artery Disease
Interventions: Drug: Ticagrelor;   Drug: Clopidogrel
17 Completed
Has Results
Study of Azacitidine in Adult Taiwanese Subjects With Higher-Risk Myelodysplastic Syndromes (MDS)
Condition: Myelodysplastic Syndromes
Intervention: Drug: Azacitidine
18 Completed Pilot Study: Effects of Psilocybin on Behavior, Psychology and Brain Function in Long-term Meditators
Conditions: Psilocybin;   Hallucinogens;   Pharmacologic Actions;   Central Nervous System Agents;   Therapeutic Uses;   Psychotropic Drugs
Intervention: Drug: psilocybin
19 Active, not recruiting Skin Cancer Prevention
Conditions: Carcinoma, Basal Cell;   Carcinoma, Squamous Cell;   Skin Neoplasms;   Skin Diseases;   Neoplasms, Basal Cell;   Neoplasms, Squamous Cell;   Carcinoma
Interventions: Drug: 5-fluorouracil;   Drug: Placebo, vehicle control
20 Recruiting Special Investigation (All Cases) of LipaCreon in Patients With Pancreatic Exocrine Insufficiency Due to Cystic Fibrosis
Conditions: Cystic Fibrosis;   Exocrine Pancreatic Insufficiency;   Pancreatic Diseases;   Digestive System Diseases
Intervention:

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Indicates status has not been verified in more than two years