82599 studies found for:    "Pharmacologic Actions"
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Rank Status Study
1 Active, not recruiting Safety and Efficacy of Oral LPCN 1021 in Men With Low Testosterone or Hypogonadism
Condition: Male Hypogonadism
Interventions: Drug: Oral testosterone undecanoate, LPCN 1021;   Drug: Topical testosterone gel 1.62 %
2 Completed Safety and Efficacy of Ledipasvir/Sofosbuvir Fixed-Dose Combination (FDC) With and Without Ribavirin for the Treatment of HCV
Condition: Chronic Hepatitis C Virus
Interventions: Drug: LDV/SOF;   Drug: RBV
3 Completed Efficacy and Safety Study to Evaluate Two Doses of Oral DMI-5207 in Adult Subjects With Diabetic Macular Edema
Condition: Diabetic Macular Edema
Intervention: Drug: Danazol
4 Recruiting A Short Term Open, Randomized Cross-over Trial Exploring the Effect of Carbonic Anhydrase Inhibition by Acetazolamide on Sleep Apnea Associated Hypertension and Vascular Dysfunction
Conditions: Obstructive Sleep Apnea;   Sleep-Disordered Breathing;   Blood Pressure;   Hypertension
Interventions: Drug: Acetazolamide;   Device: nasal Continuous Positive Airway Pressure (nCPAP)
5 Active, not recruiting Aspirin Response in High Risk Patients With Coronary Artery Disease
Conditions: Coronary Artery Disease;   Myocardial Infarction;   Diabetes Mellitus;   Renal Insufficiency, Chronic
Intervention:
6 Recruiting Modufolin (6R 5,10-Methylenetetrahydrofolate) and Pemetrexed for Neoadjuvant Rectal Cancer Treatment
Condition: Rectal Cancer
Interventions: Drug: [6R] 5,10-methylenetetrahydrofolate;   Drug: Pemetrexed
7 Suspended Daptomycin in Pediatric Patients With Bacterial Meningitis
Conditions: Meningitis;   Gram-Positive Bacteria
Intervention: Drug: Daptomycin
8 Active, not recruiting Compare Ceftazidime-Avibactam and Doripenem Followed by Oral Therapy for Hospitalized Adults With Complicated UTIs (Urinary Tract Infections)
Conditions: cUTI;   Complicated Urinary Tract Infection;   Acute Pyelonephritis
Interventions: Drug: CAZ-AVI;   Drug: Doripenem;   Drug: Either switch to oral therapy : 500 mg of Ciprofloxacin (oral);   Drug: or switch to oral therapy : 800 mg/160 mg of sulfamethoxazole/trimethoprim
9 Recruiting Phase I Study of a Dendritic Cell Vaccine for Patients With Either Newly Diagnosed or Recurrent Glioblastoma
Conditions: Glioblastoma;   Glioblastoma Multiforme;   Glioma;   Astrocytoma;   Brain Tumor
Interventions: Biological: Dendritic cell vaccination, in addition to standard temozolomide chemotherapy and involved field radiation therapy;   Biological: Dendritic cell vaccination, with optional bevacizumab treatment for patients previously treated with bevacizumab
10 Recruiting Laboratory-Treated Autologous Lymphocytes, Aldesleukin, and Sargramostim (GM-CSF) in Treating Advanced Solid Tumors
Conditions: Neoplasms;   Tumors;   Solid Tumors;   Metastatic Cancer
Intervention: Biological: EGFRBi-armed autologous activated T cells
11 Completed Zonisamide for the Treatment of Obstructive Sleep Apnea in Overweight/Obese Patients
Conditions: Sleep Apnea;   Obstructive Sleep Apnea;   Obesity
Interventions: Drug: Zonisamide;   Drug: Placebo;   Device: nCPAP
12 Completed A Safety Study Utilizing Yondelis and Doxorubicin in Patients With a Type of Cancer Called Soft Tissue Sarcoma
Conditions: Soft Tissue Sarcoma;   Sarcoma;   Neoplasms, Connective and Soft Tissue;   Neoplasms by Histologic Type;   Neoplasms
Interventions: Drug: Doxorubicin;   Drug: Trabectedin;   Drug: Dexamethasone
13 Completed Efficacy and Safety of Budesonide Foam for Patients With Active Mild to Moderate Ulcerative Proctitis or Proctosigmoiditis
Conditions: Proctitis;   Proctosigmoiditis
Interventions: Drug: Budesonide;   Drug: Placebo
14 Recruiting Research Study of IV Vitamin C in Combination With Irinotecan vs Irinotecan Alone for Advanced Colorectal CA
Condition: Stage IV Colorectal Cancer
Intervention: Drug: Vitamin C
15 Recruiting Antiplatelet Effects of Ticagrelor Versus Clopidogrel in American Indian Patients
Condition: Coronary Artery Disease
Interventions: Drug: Ticagrelor;   Drug: Clopidogrel
16 Unknown  KEEPS Cognitive and Affective Study
Conditions: Perimenopause;   Coronary Disease;   Estrogen Replacement Therapy;   Hormone Replacement Therapy
Interventions: Drug: oral conjugated equine estrogens;   Drug: transdermal estradiol;   Drug: micronized progesterone;   Other: Placebo
17 Completed
Has Results
Study of Azacitidine in Adult Taiwanese Subjects With Higher-Risk Myelodysplastic Syndromes (MDS)
Condition: Myelodysplastic Syndromes
Intervention: Drug: Azacitidine
18 Completed Pilot Study: Effects of Psilocybin on Behavior, Psychology and Brain Function in Long-term Meditators
Conditions: Psilocybin;   Hallucinogens;   Pharmacologic Actions;   Central Nervous System Agents;   Therapeutic Uses;   Psychotropic Drugs
Intervention: Drug: psilocybin
19 Completed Effect of 10mg Domperidone on Gastric Emptying of a High-fat Meal and Appetite Sensations in Healthy Adults
Condition: Diabetes Mellitus
Interventions: Drug: Domperidone 10mg;   Drug: Placebo
20 Recruiting Study of Patritumab in Combination With Erlotinib in Subjects With Locally Advanced or Metastatic Non-Small-Cell Lung Cancer (NSCLC). (HER3-Lung)
Conditions: Lung Cancer;   Non Small Cell Lung Cancer.
Interventions: Drug: Patritumab;   Drug: erlotinib:;   Drug: Placebo

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Indicates status has not been verified in more than two years