77405 studies found for:    "Pharmacologic Actions"
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Rank Status Study
1 Completed
Has Results
Prasugrel/Clopidogrel Maintenance Dose Washout Study
Condition: Coronary Artery Disease
Interventions: Drug: prasugrel;   Drug: clopidogrel
2 Active, not recruiting Study of Vorinostat (MK-0683) an HDAC Inhibitor, or Placebo in Combination With Bortezomib in Patients With Multiple Myeloma (MK-0683-088 AMN)
Condition: Multiple Myeloma
Interventions: Drug: vorinostat;   Drug: bortezomib;   Drug: placebo to vorinostat
3 Completed Zonisamide for the Treatment of Obstructive Sleep Apnea in Overweight/Obese Patients
Conditions: Sleep Apnea;   Obstructive Sleep Apnea;   Obesity
Interventions: Drug: Zonisamide;   Drug: Placebo;   Device: nCPAP
4 Recruiting Laboratory-Treated Autologous Lymphocytes, Aldesleukin, and Sargramostim (GM-CSF) in Treating Advanced Solid Tumors
Conditions: Neoplasms;   Tumors;   Solid Tumors;   Metastatic Cancer
Intervention: Biological: EGFRBi-armed autologous activated T cells
5 Recruiting A Short Term Open, Randomized Cross-over Trial Exploring the Effect of Carbonic Anhydrase Inhibition by Acetazolamide on Sleep Apnea Associated Hypertension and Vascular Dysfunction
Conditions: Obstructive Sleep Apnea;   Sleep-Disordered Breathing;   Blood Pressure;   Hypertension
Interventions: Drug: Acetazolamide;   Device: nasal Continuous Positive Airway Pressure (nCPAP)
6 Completed Efficacy and Safety Study to Evaluate Two Doses of Oral DMI-5207 in Adult Subjects With Diabetic Macular Edema
Condition: Diabetic Macular Edema
Intervention: Drug: Danazol
7 Recruiting A Study of Vitamin C in the Treatment of Liver Cancer to Determine if it is Safe and Effective
Conditions: Metastatic Hepatocellular Carcinoma;   Advanced Liver Cancer
Interventions: Drug: Ascorbic Acid + Sorafenib;   Drug: Sorafenib alone
8 Recruiting A Study of KX2-391 With Paclitaxel in Patients With Solid Tumors
Conditions: Unspecified Adult Solid Tumor, Protocol Specific;   Gastric Cancer;   Breast Cancer
Intervention: Drug: KX2-391 and Paclitaxel
9 Recruiting A Study of Brentuximab Vedotin in Patients With Relapsed or Refractory Hodgkin Lymphoma
Condition: Hodgkin Lymphoma
Intervention: Drug: Brentuximab vedotin
10 Completed A Phase 1 Dose-Escalation Study in Advanced Solid Tumors, Lymphomas or Multiple Myeloma
Conditions: Malignant Solid Tumor;   Lymphomas;   Multiple Myeloma
Interventions: Biological: AV-299;   Biological: AV-299 + erlotinib
11 Not yet recruiting Pharmacogenetic Trial of Doxazosin for Treatment of Cocaine Abuse
Condition: Cocaine Dependence
Interventions: Drug: Doxazosin;   Drug: Placebo
12 Recruiting Tranexamic Acid in Reverse Total Shoulder Arthroplasty
Conditions: Shoulder Joint Disease;   Complications; Arthroplasty;   Intraoperative Complications;   Blood Loss, Surgical
Intervention: Drug: Infusion Tranexamic acid or placebo.
13 Recruiting A Study of Intravenous Zanamivir Versus Oral Oseltamivir in Adults and Adolescents Hospitalized With Influenza
Condition: Influenza, Human
Interventions: Drug: 300mg intravenous (IV) zanamivir and oral oseltamivir placebo;   Drug: 600mg intravenous (IV) zanamivir and oral oseltamivir placebo;   Drug: 75mg oral oseltamivir and intravenous zanamivir placebo
14 Recruiting STOP-AUST: The Spot Sign and Tranexamic Acid On Preventing ICH Growth - AUStralasia Trial
Conditions: Intracerebral Haemorrhage;   Stroke
Interventions: Drug: Tranexamic Acid;   Drug: Placebo
15 Completed
Has Results
Efficacy of ArTiMist™ in Children
Condition: Falciparum Malaria
Interventions: Drug: Quinine;   Drug: Artemether
16 Completed Safety and Efficacy of Ledipasvir/Sofosbuvir Fixed-Dose Combination (FDC) With and Without Ribavirin for the Treatment of HCV
Condition: Chronic Hepatitis C Virus
Interventions: Drug: LDV/SOF;   Drug: RBV
17 Not yet recruiting Testosterone Plus Finasteride Treatment After Spinal Cord Injury
Conditions: Spinal Cord Injury;   Spinal Cord Injuries;   Trauma, Nervous System;   Wounds and Injuries;   Central Nervous System Diseases;   Nervous System Diseases;   Spinal Cord Diseases;   Gonadal Disorders;   Endocrine System Diseases;   Hypogonadism;   Genital Diseases, Male
Interventions: Drug: testosterone enanthate, finasteride;   Other: placebo
18 Terminated Efficacy and Tolerability of ABT-869 Versus Sorafenib in Advanced Hepatocellular Carcinoma (HCC)
Conditions: Hepatocellular Carcinoma Non-resectable;   Hepatocellular Carcinoma Recurrent;   Carcinoma, Hepatocellular;   Liver Diseases;   Neoplasms by Histologic Type;   Digestive System Neoplasms;   Carcinoma;   Liver Neoplasms;   Neoplasms;   Neoplasms by Site;   Digestive System Diseases;   Adenocarcinoma;   Neoplasms, Glandular and Epithelial
Interventions: Drug: ABT-869;   Drug: Sorafenib
19 Completed Caffeine for Motor Manifestations of Parkinson's Disease
Condition: Parkinson's Disease
Intervention: Drug: Caffeine alkaloid
20 Completed Study of Safety, Tolerability, and Anti-Viral Effect of Locteron Compared to PEG-Intron in Patients With Chronic Hepatitis C
Condition: Hepatitis C
Interventions: Other: Locteron (controlled-release interferon alpha 2b);   Biological: pegylated IFNa2b

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Indicates status has not been verified in more than two years