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626 studies found for:    "Narcotic Antagonists"

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Rank Status Study
1 Terminated Opioid Agonist and Antagonist Effects on Opioid Dependence
Condition: Opioid-Related Disorders
Interventions: Drug: Methadone;   Drug: Full opioid agonist;   Drug: Partial opioid agonist;   Drug: Opioid antagonist
2 Completed An Open-Label Evaluation of the Independent Effects of Coadministration of a High-Fat Meal and Naltrexone Blockade on the Pharmacokinetic Profile of Dilaudid OROS (Hydromorphone HCI) 16mg
Condition: Analgesia
Intervention: Drug: Hydromorphone HCL 16mg; Dilaudid SR 16mg; Naltrexone (opioid antagonist) 50mg.
3 Completed An Open-Label Evaluation of the Dose Proportionality of OROS� Hydromorphone HCL Tablets 8mg, 16mg, 32mg, 64mg
Condition: Analgesia
Intervention: Drug: OROS® Hydromorphone HCL; OROS® Dilaudid; Dilaudid SR (slow release); Naltrexone (an opioid antagonist).
4 Active, not recruiting Cardiovascular Outcomes Study of Naltrexone SR/Bupropion SR in Overweight and Obese Subjects With Cardiovascular Risk Factors (The Light Study)
Conditions: Obesity;   Overweight
Interventions: Drug: NB32;   Drug: PBO;   Behavioral: Weight Management Program
5 Completed Medications Development for the Treatment of Cannabis Related Disorders
Conditions: Nicotine Withdrawal;   Marijuana Dependence;   Cannabis Dependence;   Nicotine Dependence;   Cannabis Abuse
Interventions: Drug: Placebo Aprepitant;   Drug: Active Aprepitant
6 Recruiting Comparison of Two Naloxone Infusion Rates on the Postoperative Recovery of Patients Undergoing Spine Fusion Surgery
Conditions: Pain, Postoperative;   Postoperative Nausea and Vomiting;   Scoliosis
Intervention: Drug: Naloxone
7 Recruiting Methylnaltrexone for Opioid-induced Constipation in Cancer Patients
Conditions: Neoplasms;   Constipation;   Opioid-Related Disorders
Intervention: Drug: Methylnaltrexone bromide
8 Recruiting Prevention of Stimulant-Induced Euphoria With an Opioid Receptor Antagonist
Conditions: ADHD;   Stimulant-Induced Euphoria
Interventions: Drug: SODAS MPH;   Drug: Naltrexone
9 Active, not recruiting Buprenorphine's Dose Response Curve
Condition: Opioid-related Disorders
Interventions: Drug: Buprenorphine;   Drug: Morphine;   Drug: Placebo
10 Completed Naloxone and Intravenous Methylnaltrexone Effects on Bladder Function
Condition: Healthy Males
Interventions: Drug: Naloxone;   Drug: IV Methylnaltrexone (MNTX);   Drug: Placebo
11 Terminated Naltrexone in Borderline Personality Disorder
Condition: Borderline Personality Disorder
Intervention: Drug: Naltrexone
12 Completed Evaluation of the Efficacy and Safety of ADL5945 for the Treatment of Opioid-induced Constipation in Adults Taking Opioid Therapy for Chronic Noncancer Pain
Condition: Opioid Induced Constipation
Interventions: Drug: Placebo;   Drug: ADL5945 0.1 mg;   Drug: ADL5945 0.25 mg
13 Completed Evaluation of the Efficacy and Safety of ADL5945 Once Daily for the Treatment of Opioid-induced Constipation in Adults Taking Opioid Therapy for Chronic Noncancer Pain
Condition: Constipation
Interventions: Drug: Placebo;   Drug: ADL5945 0.25 mg
14 Unknown † Naltrexone Implants as Relapse Prevention
Condition: Opioid Dependency
Intervention: Drug: Implantation of naltrexone implants
15 Active, not recruiting Investigation of Naltrexone for Pathological Gambling
Condition: Pathological Gambling
Interventions: Drug: Naltrexone;   Other: Placebo
16 Completed Opioids and Esophageal Function
Conditions: Pharyngeal Dysfunction;   Esophageal Dysfunction
Intervention: Drug: methylnaltrexone
17 Unknown † HIV Risk Reduction and Drug Abuse Treatment in Iran
Conditions: Opiate Dependence;   HIV Infections
Interventions: Drug: Buprenorphine/Subutex;   Drug: Naltrexone;   Behavioral: Drug counseling
18 Completed Effectiveness of Alcohol Interventions Among Tuberculosis (TB) Patients in Tomsk Oblast, Russia
Conditions: Tuberculosis;   Alcohol Use Disorders
Interventions: Behavioral: Brief Counseling Intervention (BCI);   Drug: Naltrexone;   Other: BCI + Naltrexone;   Behavioral: Treatment as Usual
19 Completed Oxycodone-naloxone Prolonged Release Tablets in Relieving Opioid-related Constipation
Condition: Pain
Intervention: Drug: Oxycodone naloxone prolonged release tablets (OXN)
20 Completed Induction of Opioid-Dependent Individuals Onto Buprenorphine and Buprenorphine/Naloxone
Condition: Opioid-Related Disorders
Interventions: Drug: Buprenorphine;   Drug: Buprenorphine/Naloxone
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† Indicates status has not been verified in more than two years