46117 studies found for:    "Molecular Mechanisms of Pharmacological Action"
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Study Details
Participant Details
Identifiers
Dates
Rank Status Study
1 Completed Study in Infants With Infantile Hemangioma to Compare Propranolol Gel to Placebo
Condition: Infantile Hemangioma
Interventions: Drug: propranolol gel;   Drug: Placebo
2 Completed Safety and Efficacy of Ledipasvir/Sofosbuvir Fixed-Dose Combination ± Ribavirin for the Treatment of HCV (ION-3)
Condition: Chronic Hepatitis C Virus
Interventions: Drug: LDV/SOF;   Drug: RBV
3 Completed
Has Results
Sofosbuvir (GS-7977) in Combination With PEG and Ribavirin for 12 Weeks in Treatment Experienced Subjects With Chronic HCV Infection Genotype 2 or 3
Condition: Hepatitis C
Interventions: Drug: SOF;   Drug: PEG;   Drug: RBV
4 Active, not recruiting A Phase 1b/2 Study in Asian Subjects With Non-Small Cell Lung Cancer
Conditions: Carcinoma, Non-Small Cell-Lung;   Lung Neoplasms;   Lung Cancer;   Respiratory Tract Neoplasms
Interventions: Biological: AV-299 + gefitinib;   Drug: Gefitinib
5 Unknown  Cardiovascular Effects of Salvia Miltiorrhiza Extract (Danshen)
Conditions: Dyslipidemias;   Hypertension;   Vasodilation;   Oxidative Stress;   Inflammation
Interventions: Dietary Supplement: Salvia miltiorrhiza extract;   Dietary Supplement: Placebo
6 Active, not recruiting Tecemotide (L-BLP25) in Rectal Cancer
Condition: Rectal Cancer
Interventions: Other: Chemoradiation Therapy;   Drug: Cyclophosphamide (CPA);   Other: Biological: Tecemotide (L-BLP25)
7 Completed A Study of MK-0893 on Glucagon-Induced Glycemic Excursion in Healthy Male Participants Following Intravenous Administration of Glucagon, Sandostatine® and Insulin (MK-0893-002)
Condition: Type 2 Diabetes Mellitus
Interventions: Drug: MK-0893 10 mg;   Drug: MK-0893 40 mg;   Drug: MK-0893 200 mg;   Drug: MK-0893 1000 mg;   Drug: Placebo;   Biological: Sandostatine®;   Biological: Insulin;   Biological: Glucagon
8 Completed Phase I/II Study of KRN330 Plus Irinotecan in Patients With Metastatic Colorectal Cancer
Condition: Colorectal Cancer
Interventions: Biological: KRN330;   Drug: Irinotecan
9 Terminated Efficacy and Tolerability of ABT-869 Versus Sorafenib in Advanced Hepatocellular Carcinoma (HCC)
Conditions: Hepatocellular Carcinoma Non-resectable;   Hepatocellular Carcinoma Recurrent;   Carcinoma, Hepatocellular;   Liver Diseases;   Neoplasms by Histologic Type;   Digestive System Neoplasms;   Carcinoma;   Liver Neoplasms;   Neoplasms;   Neoplasms by Site;   Digestive System Diseases;   Adenocarcinoma;   Neoplasms, Glandular and Epithelial
Interventions: Drug: ABT-869;   Drug: Sorafenib
10 Recruiting Potentiation of Quetiapine Treatment With Lithium or Aripiprazole in Bipolar 1 Nonresponders Patients
Condition: Bipolar I Disorder
Interventions: Drug: Lithium;   Drug: Aripiprazole
11 Completed
Has Results
Modulation of Breast Cancer Risk Biomarkers by High Dose Vitamin D
Condition: Breast Cancer
Intervention: Drug: vitamin D3
12 Withdrawn Melatonin Supplementation to Improve Sleep in Patients With Heart Failure
Conditions: Heart Failure;   Sleep Disorders
Interventions: Drug: melatonin;   Drug: placebo
13 Recruiting Tranexamic Acid in Reverse Total Shoulder Arthroplasty
Conditions: Shoulder Joint Disease;   Complications; Arthroplasty;   Intraoperative Complications;   Blood Loss, Surgical
Intervention: Drug: Infusion Tranexamic acid or placebo.
14 Recruiting Pharmacogenetic Trial of Doxazosin for Treatment of Cocaine Abuse
Condition: Cocaine Dependence
Interventions: Drug: Doxazosin;   Drug: Placebo
15 Recruiting Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of GS-9857 in Subjects With Chronic Hepatitis C Virus Infection
Condition: Hepatitis C Virus Infection
Interventions: Drug: GS-9857;   Drug: Placebo to match GS-9857
16 Recruiting A Study of Vitamin C in the Treatment of Liver Cancer to Determine if it is Safe and Effective
Conditions: Metastatic Hepatocellular Carcinoma;   Advanced Liver Cancer
Interventions: Drug: Ascorbic Acid + Sorafenib;   Drug: Sorafenib alone
17 Completed
Has Results
Study of Azacitidine in Adult Taiwanese Subjects With Higher-Risk Myelodysplastic Syndromes (MDS)
Condition: Myelodysplastic Syndromes
Intervention: Drug: Azacitidine
18 Completed Pharmacokinetics, Safety and Tolerability of Escalating Rifapentine Doses in Healthy Volunteers
Conditions: Tuberculosis;   Tuberculosis, Pulmonary
Interventions: Drug: Rifampin & midazolam;   Drug: rifapentine & midazolam;   Drug: rifapentine and midazolam
19 Completed
Has Results
A Study to Assess the Safety, Tolerability and Glucose-Lowering Efficacy of MK-0893 in Participants With Type 2 Diabetes Mellitus (MK-0893-005)
Condition: Type 2 Diabetes Mellitus
Interventions: Drug: MK-0893;   Drug: Metformin;   Drug: Placebo
20 Completed Safety and Efficacy of Ledipasvir/Sofosbuvir Fixed-Dose Combination ± Ribavirin for the Treatment of HCV
Condition: Chronic Hepatitis C Virus
Interventions: Drug: Ledipasvir/sofosbuvir;   Drug: RBV

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