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13 studies found for:    "BMS-708163"

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1 Completed Study to Evaluate the Safety, Pharmacokinetics and Tolerability of BMS-708163
Condition: Alzheimer's Disease
Interventions: Drug: BMS-708163 (Gamma-Secretase Inhibitor);   Drug: Placebo matching BMS-708163
2 Completed Drug-Drug Interaction (DDI) w/Ketoconazole or Fluconazole
Condition: Alzheimer Disease
Interventions: Drug: BMS-708163;   Drug: BMS-708163 + Ketoconazole;   Drug: Ketoconazole;   Drug: Fluconazole;   Drug: BMS-708163 + Fluconazole
3 Completed Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of BMS-708163
Condition: Alzheimer's Disease
Interventions: Drug: BMS-708163;   Drug: Placebo
4 Completed A Phase II, Multicenter, Double Blind, Placebo-Controlled Safety, Tolerability Study of BMS-708163 in Patients With Mild to Moderate Alzheimer's Disease
Condition: Alzheimer's Disease
Interventions: Drug: BMS-708163;   Drug: Placebo
5 Completed Safety Study of Multiple-dose of Gamma-secretase Inhibitor in Healthy Male Japanese and Healthy Elderly Japanese
Condition: Healthy
Interventions: Drug: BMS-708163;   Drug: Placebo
6 Completed Effect on the Electrocardiographic QT Interval Corrected for Heart Rate (QTc) in Healthy Subjects
Condition: Alzheimer Disease
Interventions: Drug: BMS-708163;   Drug: Placebo;   Drug: Moxifloxacin
7 Completed Relative Bioavailability Study of Four Experimental Formulations for Alzheimer's Disease
Conditions: Alzheimer's Disease;   Healthy
Intervention: Drug: BMS-708163
8 Completed Drug Interaction Study With a Potential Alzheimer's Disease Compound
Condition: Alzheimer Disease
Interventions: Drug: Interacting drugs - Cooperstown Cocktail (midazolam, warfarin, (+ vitamin K), caffeine, omeprazole and dextromethorphan);   Drug: BMS-708163;   Drug: BMS-708163 + Cooperstown Cocktail
9 Completed Drug-Drug Interaction to Study the Effect of BMS-708163 on Pharmacokinetics (PK) of Galantamine Extended Release (ER)
Condition: Alzheimer Disease
Interventions: Drug: galantamine;   Drug: BMS-708163
10 Completed Drug-Drug Interaction Study With Rifampin
Condition: Alzheimer Disease
Interventions: Drug: BMS-708163;   Drug: Rifampin
11 Completed Multiple Dose Japanese Bridging Study
Condition: Alzheimer Disease
Interventions: Drug: BMS-708163;   Drug: Placebo
12 Completed Drug-Drug Interaction Study With Aricept® (Donepezil)
Condition: Alzheimer Disease
Interventions: Drug: Donepezil;   Drug: BMS-708163
13 Active, not recruiting A Multicenter, Double Blind, Placebo-Controlled, Safety and Tolerability Study of BMS-708163 in Patients With Prodromal Alzheimer's Disease
Condition: Alzheimer's Disease
Interventions: Drug: Avagacestat;   Drug: Placebo
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† Indicates status has not been verified in more than two years