213 studies found for:    heart surgery OR coronary artery bypass surgery OR heart transplant | Open Studies | NIH, U.S. Fed
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Rank Status Study
1 Recruiting Stem Cell Injection to Treat Heart Damage During Open Heart Surgery
Conditions: Heart Disease;   Ischemic Heart Disease;   Coronary Artery Disease;   Coronary Artery Disease (CAD)
Intervention: Other: Cell Therapy
2 Recruiting Allo-antibodies in Pediatric Heart Transplantation
Condition: Pediatric Heart Transplantation
Interventions: Drug: Induction Therapy (anti-T cell antibody induction);   Drug: Tacrolimus (Prograf);   Drug: Mycophenolate Mofetil- MMF (CellCept);   Procedure: Intraoperative plasma exchange/pheresis;   Procedure: Short-term post-operative plasmapheresis;   Drug: Post-transplant course of intravenous immunoglobulin (IVIG) therapy.;   Drug: Prednisone
3 Recruiting Study of Heart Transplant Rejection
Condition: Heart Transplantation
Intervention:
4 Recruiting Prevention of Cardiac Allograft Vasculopathy Using Rituximab (Rituxan) Therapy in Cardiac Transplantation
Condition: Cardiac Allograft Vasculopathy
Interventions: Biological: Rituximab induction/conventional immunosuppression (tacrolimus, MMF, and steroid taper);   Drug: Rituximab placebo/conventional immunosuppression (tacrolimus, MMF, and steroid taper)
5 Unknown  Fish Oil In Heart Transplantation
Condition: Myocardial Tissue in Heart Transplantation
Intervention: Dietary Supplement: Fish Oil
6 Recruiting Safety and Efficacy of Desensitization Therapy in Sensitized Participants Awaiting Heart Transplantation
Conditions: Transplantation;   Organ Transplantation;   Heart Transplantation
Interventions: Drug: Bortezomib;   Procedure: Plasmapheresis on days 0, 1 and 2.
7 Recruiting Stroke Study: Operative Strategies to Reduce Cerebral Embolic Events During Coronary Artery Bypass Surgery
Condition: Stroke
Interventions: Procedure: No aortic clamping;   Procedure: partial occluding clamp;   Procedure: single cross clamp;   Procedure: cross clamp and partial occluding clamp
8 Recruiting Aspirin and Plavix Following Coronary Artery Bypass Grafting
Condition: Coronary Graft Patency
Interventions: Drug: clopidogrel;   Drug: sugar pill
9 Unknown  Heartsbreath Test for Heart Transplant Rejection
Condition: Heart Transplant Rejection
Intervention:
10 Recruiting Proteolytic Enzyme Induction Within the Human Myocardial Interstitium
Condition: Heart Disease
Intervention:
11 Recruiting Targeted, Highly Sensitive, Non-Invasive Cardiac Transplant Rejection Monitoring
Conditions: Cardiovascular Disease;   Acute Rejection of Cardiac Transplant;   Cardiac Transplant Rejection;   Heart Transplant Failure and Rejection
Intervention:
12 Unknown  Continuous Glucose Monitoring Technology in the Perioperative Period During Cardiac Surgery
Condition: Cardiac Surgery
Intervention: Device: Use of continuous glucose monitor during surgery. ( Medtronic Minimed Guardian REALTime Continuous Glucose Monitor)
13 Recruiting Home Electrocardiogram (ECG) Monitoring After Heart Transplantation
Conditions: Cardiac Transplant Rejection;   Qt Interval, Variation in
Intervention:
14 Recruiting Pediatric Heart Transplantation: Transitioning to Adult Care
Condition: Heart Transplantation
Intervention: Behavioral: TRANSIT
15 Recruiting Identification of Genomic Predictors of Adverse Events After Cardiac Surgery
Conditions: Heart; Dysfunction Postoperative, Cardiac Surgery;   Genetic Predisposition to Disease;   Atrial Fibrillation;   Myocardial Infarction;   Heart Failure
Intervention:
16 Recruiting Prasugrel for Prevention of Early Saphenous Vein Graft Thrombosis
Condition: Coronary Artery Bypass
Interventions: Drug: Prasugrel;   Drug: Placebo
17 Not yet recruiting Optimizing Prevention of Healthcare-Acquired Infections After Cardiac Surgery (HAI)_2
Conditions: Cardiovascular Disease;   Healthcare Associated Infectious Disease;   Sternal Superficial Wound Infection;   Deep Sternal Infection;   Mediastinitis;   Thoracotomy;   Conduit Harvest or Cannulation Site;   Sepsis;   Pneumonia
Intervention: Other: There is no intervention. The investigators are interviewing cardiac surgery staff with knowledge of infection prevention.
18 Not yet recruiting Optimizing Prevention of Healthcare-Acquired Infections After Cardiac Surgery
Conditions: Healthcare Associated Infectious Disease;   Sternal Superficial Wound Infection;   Sepsis;   Pneumonia;   Deep Sternal Infection
Intervention:
19 Recruiting Cerebral Autoregulation Monitoring During Cardiac Surgery
Conditions: Thoracic Surgery;   Cardiopulmonary Bypass
Interventions: Other: blood pressure maintenance based on cerebral blood flow autoregulation measurement;   Other: Control group
20 Not yet recruiting ISCHEMIA-Chronic Kidney Disease Trial
Conditions: Cardiovascular Diseases;   Coronary Artery Disease;   Heart Diseases;   Myocardial Ischemia;   Kidney Disease;   End Stage Renal Failure on Dialysis
Interventions: Procedure: Cardiac Catheterization;   Procedure: Coronary Artery Bypass Graft Surgery;   Procedure: Percutaneous Coronary Intervention;   Behavioral: Lifestyle;   Drug: Medication

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Indicates status has not been verified in more than two years