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79 studies found for:    congenital heart defects OR congenital heart disease OR valve defects | Open Studies | NIH, U.S. Fed

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Rank Status Study
1 Recruiting Myocardial Perfusion and Scarring in Congenital Heart Disease
Condition: Congenital Heart Disease
Intervention:
2 Unknown † Examining Developmental Changes in Heart Contractions of Children With Congenital Heart Defects
Conditions: Hypoplastic Left Heart Syndrome;   Tetralogy of Fallot
Intervention:
3 Recruiting Congenital Heart Disease GEnetic NEtwork Study (CHD GENES)
Condition: Congenital Heart Defects
Intervention:
4 Recruiting Association Between a Mother's Exposure to "Strep Throat" and Her Baby's Developing Heart Disease
Condition: Congenital Heart Disease in Pregnancy
Intervention:
5 Recruiting Spironolactone in Adult Congenital Heart Disease
Conditions: Congenital Heart Disease;   Heart Failure;   Endomyocardial Fibrosis
Interventions: Drug: Spironolactone;   Other: Placebo
6 Recruiting Cardiovascular Disease Screening
Conditions: Congenital Heart Disease;   Atherosclerosis;   Myocardial Ischemia;   Myocardial Infarction;   Acquired Heart Disease
Intervention:
7 Recruiting Corticosteroid Therapy in Neonates Undergoing Cardiopulmonary Bypass
Conditions: Congenital Heart Disease;   Disorder of Fetus or Newborn
Interventions: Drug: Methylprednisolone;   Drug: Placebo
8 Recruiting SVRII Family Factors Study
Condition: Hypoplastic Left Heart Syndrome
Intervention:
9 Recruiting Real-time MRI Right Heart Catheterization Using Passive Catheters
Conditions: Caridovascular Disease;   Congenital Heart Disease;   Pulmonary Hypertension
Interventions: Device: Balloon catheter for right heart catheterization;   Drug: Gadopentate Dimeglumine (Gadolinium); Contrast Agent;   Procedure: Right Heart Catheterization;   Procedure: Cardiac Real-time MRI;   Procedure: Vascular Hemostasis
10 Recruiting National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions
Conditions: Marfan Syndrome;   Turner Syndrome;   Ehlers-Danlos Syndrome;   Loeys-Dietz Syndrome;   FBN1, TGFBR1, TGFBR2, ACTA2 or MYH11 Genetic Mutation;   Bicuspid Aortic Valve Without Known Family History;   Bicuspid Aortic Valve With Family History;   Bicuspid Aortic Valve With Coarctation;   Familial Thoracic Aortic Aneurysm and Dissections;   Shprintzen-Goldberg Syndrome;   Other Aneurysms and Dissections of the Thoracic Aorta Not Due to Trauma, <50yo;   Other Congenital Heart Disease
Intervention:
11 Unknown † Examining Genetic Factors That Affect the Severity of 22q11.2 Deletion Syndrome
Conditions: DiGeorge Syndrome;   22q11.2 Deletion Syndrome
Intervention:
12 Recruiting Clinical and Genetic Studies of VACTERL Association
Conditions: Congenital Abnormalities;   Birth Defects;   Congenital Defects
Intervention:
13 Unknown † Study of Energy Expenditure in Infants With Ventricular Septal Defects
Condition: Heart Septal Defects, Ventricular
Intervention:
14 Unknown † Immunologic Evaluation in Patients With DiGeorge Syndrome or Velocardiofacial Syndrome
Conditions: DiGeorge Syndrome;   Shprintzen Syndrome;   Chromosome Abnormalities;   Abnormalities, Multiple;   Conotruncal Cardiac Defects
Intervention:
15 Unknown † Genetic Study of the FBN1 Gene and Fibrillin-1 Abnormalities in Choctaw Native Americans and Other Patients With Systemic Sclerosis
Condition: Systemic Sclerosis
Intervention:
16 Recruiting Thymus Transplantation Safety-Efficacy
Conditions: Complete DiGeorge Anomaly;   DiGeorge Syndrome;   DiGeorge Anomaly;   Complete DiGeorge Syndrome
Interventions: Biological: Thymus Tissue for Transplantation;   Procedure: Blood Draw;   Drug: Rabbit anti-thymocyte globulin;   Drug: Cyclosporine;   Drug: Tacrolimus;   Drug: Methylprednisolone or Prednisolone;   Drug: Basiliximab;   Drug: Mycophenolate mofetil
17 Recruiting Clinical and Molecular Manifestations of Heritable Disorders of Connective Tissue
Conditions: Ehlers-Danlos Syndrome;   Stickler Syndrome;   Marfan Syndrome
Intervention:
18 Recruiting Clinical Study of Y Chromosome Variants and Infertility
Conditions: Male Factor Infertility;   Female Factor Infertility;   Turner Syndrome
Intervention:
19 Recruiting Clinical Proteomic Research for the Brain
Conditions: Ischemic Brain Injury;   Stroke;   Healthy Individual;   Patent Foramen Ovale (PFO);   Neurovascular Injury
Intervention:
20 Recruiting Pathogenesis of Primary Ciliary Dyskinesia (PCD) Lung Disease
Condition: Kartagener Syndrome
Intervention:
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† Indicates status has not been verified in more than two years