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130 studies found for:    anemia OR aplastic anemia OR iron-defiency OR sickle cell OR fanconi anemia OR pernicious anemia | Open Studies | NIH, U.S. Fed

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Rank Status Study
1 Recruiting Secondary Pulmonary Hypertension in Adults With Sickle Cell Anemia
Conditions: Pulmonary Hypertension;   Sickle Cell Anemia
Intervention:
2 Recruiting A Single Dose Study of the Safety, Blood Levels and Biological Effects of Aes-103 Compared to Placebo in Subjects With Stable Sickle Cell Disease
Condition: Anemia, Sickle Cell
Interventions: Drug: Aes-103;   Drug: Placebo
3 Recruiting Blood Flow and Pain Crises in People With Sickle Cell Disease
Condition: Sickle Cell Disease
Intervention:
4 Recruiting Eltrombopag for Moderate Aplastic Anemia
Conditions: Eltrombopag;   Aplastic Anemia;   Aplastic Anemia Treatment;   Moderate Aplastic Anemia;   Moderate Aplastic Anemia Treatment
Intervention: Drug: Eltrombopag
5 Recruiting Alemtuzumab to Treat Severe Aplastic Anemia
Conditions: Relapsed or Refractory Severe Aplastic Anemia;   Severe Aplastic Anemia
Intervention: Drug: Alemtuzumab (Campath(Registered Trademark))
6 Recruiting Nonmyeloablative Haploidentical Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Severe Congenital Anemias Including Sickle Cell Disease and Beta-Thalassemia
Conditions: Peripheral Blood Stem Cell Transplantation;   Anemia, Sickle Cell;   Graft-Versus-Host Disease;   Sirolimus (Rapamune(Registered Trademark));   Alemtuzumab (Campath(Registered Trademark))
Interventions: Procedure: PBMC Transplant;   Drug: Alemtuzumab (Campath(Registered Trademark));   Drug: Sirolimus (Rapamune(Registered Trademark));   Drug: Cyclophosphamide (Cytoxan(Registered Trademark));   Procedure: Low Dose Irradiation
7 Recruiting Eltrombopag With Standard Immunosuppression for Severe Aplastic Anemia
Conditions: Aplastic Anemia;   Neutropenia;   Pancytopenia;   Anemia;   Thrombocytopenia
Interventions: Drug: Eltrombopag;   Drug: Horse Anti-Thymocyte Globulin (ATG);   Drug: Cyclosporine A (CSA)
8 Recruiting Stem Cell Transplant Using Peripheral and Cord Blood Stem Cells to Treat Severe Aplastic Anemia and Myelopdysplastic Syndrome
Conditions: Myelodysplastic Syndrome (MDS);   Severe Aplastic Anemia (SAA)
Interventions: Other: Umbilical Cord Blood;   Other: Haploidentical Stem Cells;   Device: Miltenvi CliniMACs CD34 Reagent System
9 Recruiting Horse ATG/CsA in Aplastic Anemia Patients Unresponsive to or With a Suboptimal Response to Rabbit ATG/CsA Treatment
Conditions: Anemia, Aplastic;   Anemia, Hypoplastic
Interventions: Drug: h-ATG (ATGAM(Registered Trademark));   Drug: Cyclosporine (Gengraf(Registered Trademark))
10 Recruiting Cancer in Inherited Bone Marrow Failure Syndromes
Conditions: Fanconi's Anemia;   Anemia, Diamond Blackfan;   Dyskeratosis Congenital;   Thrombocytopenia;   Neutropenia
Intervention:
11 Recruiting A Pilot Study of a Thrombopoietin-Receptor Agonist (TPO-R Agonist), Eltrombopag, in Aplastic Anemia Patients With Immunosuppressive-Therapy Refractory Thrombocytopenia
Conditions: Anemia, Aplastic;   Anemia, Hypoplastic;   Thrombocytopenia
Interventions: Drug: Eltrombopag (Promacta);   Drug: Eltrombopag
12 Recruiting Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-cells
Conditions: Severe Aplastic Anemia;   MDS (Myelodysplastic Syndrome)
Interventions: Device: Miltenyi CD34 Reagent System;   Other: Donor derived G-CSF mobilized PBC
13 Unknown † Phase I/II Randomized Study of Hydroxyurea With or Without Clotrimazole in Patients With Sickle Cell Anemia
Condition: Sickle Cell Anemia
Interventions: Drug: clotrimazole;   Drug: hydroxyurea
14 Recruiting Natural History of Sickle Cell Disease and Other Hemolytic Disorders
Conditions: Hemoglobin SC Disease;   Hematologic Diseases;   Sickle Cell Anemia;   Hemolytic Anemia
Intervention:
15 Unknown † Sirolimus and Cyclosporine for Treatment-Resistant Aplastic Anemia
Condition: Anemia, Aplastic
Interventions: Drug: Sirolimus;   Drug: Cyclosporine
16 Recruiting Topical Sodium Nitrite for Chronic Leg Ulcers in Adult Patients With Blood Disorders
Conditions: Sickle Cell Anemia;   Sickle Cell Disease;   Chronic Hemolytic Disorders
Intervention: Drug: Sodium Nitrite Cream
17 Recruiting Genetics and Pain Severity in Sickle Cell Disease
Conditions: Genotype;   Pain;   Sickle Cell Anemia;   Vaso-Occlusive Pain Crisis
Intervention:
18 Unknown † Effectiveness of a Computerized Tool (PAINRelieveIt) to Help Manage Pain Related to Sickle Cell Disease
Conditions: Anemia, Sickle Cell;   Hemoglobin SC Disease
Interventions: Behavioral: PAINReportIt;   Behavioral: PAINUCope;   Behavioral: PAINConsultN
19 Recruiting Carbon Monoxide Levels and Sickle Cell Disease Severity
Conditions: Sickle Cell Disease;   Sickle Cell Anemia;   Anemia, Sickle Cell
Intervention:
20 Unknown † The Link Between Anemia and Deficits in Memory and Attention in Individuals With Sickle Cell Disease
Condition: Sickle Cell Disease
Intervention:
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† Indicates status has not been verified in more than two years