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157 studies found for:    "CINJ" OR "Cancer Intitute of New Jersey" | Open Studies | United States, New Jersey

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41 Recruiting Cisplatin and Etoposide With or Without Veliparib in Treating Patients With Extensive Stage Small Cell Lung Cancer or Metastatic Large Cell Neuroendocrine Non-Small Cell Lung Cancer
Conditions: Extensive Stage Small Cell Lung Cancer;   Large Cell Lung Cancer;   Metastatic Carcinoma of Unknown Primary;   Neuroendocrine Carcinoma;   Newly Diagnosed Carcinoma of Unknown Primary
Interventions: Drug: veliparib;   Other: placebo;   Drug: etoposide;   Drug: cisplatin;   Other: laboratory biomarker analysis;   Procedure: quality-of-life assessment;   Other: questionnaire administration
Study Type: Interventional
Phases: Phase 1 / Phase 2
Funder Type: NIH
Study Design: Allocation: Randomized;   Endpoint Classification: Safety/Efficacy Study;   Intervention Model: Single Group Assignment;   Masking: Open Label;   Primary Purpose: Treatment
Number Enrolled: 168
Gender: Both
Age Groups: Adult / Senior
NCT Number: NCT01642251
42 Recruiting Combination Chemotherapy in Treating Patients With Non-Metastatic Extracranial Ewing Sarcoma
Conditions: Brain and Central Nervous System Tumors;   Kidney Cancer;   Sarcoma
Interventions: Drug: cyclophosphamide;   Drug: doxorubicin hydrochloride;   Drug: etoposide;   Drug: ifosfamide;   Drug: topotecan hydrochloride;   Drug: vincristine sulfate
Study Type: Interventional
Phase: Phase 3
Funder Type: Other / NIH
Study Design: Allocation: Randomized;   Masking: Open Label;   Primary Purpose: Treatment
Number Enrolled: 630
Gender: Both
Age Groups: Child / Adult
NCT Number: NCT01231906
43 Recruiting Chemotherapy and Radiation Therapy in Treating Young Patients With Newly Diagnosed, Previously Untreated, High-Risk Medulloblastoma or Supratentorial Primitive Neuroectodermal Tumor
Condition: Brain and Central Nervous System Tumors
Interventions: Biological: filgrastim;   Drug: carboplatin;   Drug: cisplatin;   Drug: cyclophosphamide;   Drug: isotretinoin;   Drug: vincristine sulfate;   Radiation: radiation therapy
Study Type: Interventional
Phase: Phase 3
Funder Type: Other / NIH
Study Design: Allocation: Randomized;   Masking: Open Label;   Primary Purpose: Treatment
Number Enrolled: 300
Gender: Both
Age Groups: Child / Adult
NCT Number: NCT00392327
44 Recruiting Risk-Based Classification System of Patients With Newly Diagnosed Acute Lymphoblastic Leukemia
Condition: Leukemia
Interventions: Genetic: DNA ploidy analysis;   Genetic: chromosomal translocation analysis;   Genetic: cytogenetic analysis;   Genetic: fluorescence in situ hybridization;   Other: cytology specimen collection procedure;   Other: flow cytometry;   Other: laboratory biomarker analysis
Study Type: Observational
Phase:
Funder Type: Other / NIH
Study Design:
Number Enrolled: 11500
Gender: Both
Age Groups: Child / Adult
NCT Number: NCT01142427
45 Recruiting Risk-Adapted Chemotherapy in Younger Patients With Newly Diagnosed Standard-Risk Acute Lymphoblastic Leukemia
Condition: Leukemia
Interventions: Drug: cyclophosphamide;   Drug: cytarabine;   Drug: dexamethasone;   Drug: doxorubicin hydrochloride;   Drug: leucovorin calcium;   Drug: mercaptopurine;   Drug: methotrexate;   Drug: pegaspargase;   Drug: thioguanine;   Drug: vincristine sulfate
Study Type: Interventional
Phase: Phase 3
Funder Type: Other / NIH
Study Design: Allocation: Randomized;   Masking: Open Label;   Primary Purpose: Treatment
Number Enrolled: 5760
Gender: Both
Age Group: Child
NCT Number: NCT01190930
46 Recruiting Vincristine, Dactinomycin, and Doxorubicin With or Without Radiation Therapy or Observation Only in Treating Younger Patients Who Are Undergoing Surgery for Newly Diagnosed Stage I, Stage II, or Stage III Wilms Tumor
Condition: Kidney Cancer
Interventions: Biological: dactinomycin;   Drug: doxorubicin hydrochloride;   Drug: vincristine sulfate;   Procedure: therapeutic conventional surgery;   Radiation: external beam radiation therapy
Study Type: Interventional
Phase: Phase 3
Funder Type: Other / NIH
Study Design: Masking: Open Label;   Primary Purpose: Treatment
Number Enrolled: 875
Gender: Both
Age Groups: Child / Adult
NCT Number: NCT00352534
47 Recruiting Comparison of Radiation Therapy Regimens in Combination With Chemotherapy in Treating Young Patients With Newly Diagnosed Standard-Risk Medulloblastoma
Condition: Brain and Central Nervous System Tumors
Interventions: Drug: cisplatin;   Drug: cyclophosphamide;   Drug: lomustine;   Drug: vincristine sulfate;   Radiation: radiation therapy
Study Type: Interventional
Phase: Phase 3
Funder Type: Other / NIH
Study Design: Allocation: Randomized;   Primary Purpose: Treatment
Number Enrolled: 510
Gender: Both
Age Groups: Child / Adult
NCT Number: NCT00085735
48 Recruiting Combination Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Rhabdomyosarcoma
Condition: Sarcoma
Interventions: Biological: dactinomycin;   Drug: cyclophosphamide;   Drug: irinotecan hydrochloride;   Drug: vincristine sulfate;   Radiation: radiation therapy
Study Type: Interventional
Phase: Phase 3
Funder Type: Other / NIH
Study Design: Allocation: Randomized;   Primary Purpose: Treatment
Number Enrolled: 486
Gender: Both
Age Groups: Child / Adult
NCT Number: NCT00354835
49 Recruiting Biomarkers in Tumor Tissue Samples From Patients With Newly Diagnosed Neuroblastoma or Ganglioneuroblastoma
Condition: Neuroblastoma
Interventions: Genetic: fluorescence in situ hybridization;   Genetic: gene expression analysis;   Genetic: nucleic acid amplification;   Genetic: polymerase chain reaction;   Genetic: reverse transcriptase-polymerase chain reaction;   Other: cytology specimen collection procedure;   Other: flow cytometry;   Procedure: biopsy
Study Type: Observational
Phase:
Funder Type: Other / NIH
Study Design:
Number Enrolled: 10000
Gender: Both
Age Groups: Child / Adult
NCT Number: NCT00904241
50 Unknown † Study of Late-Occurring Complications in Childhood Cancer Survivors
Condition: Cancer
Interventions: Genetic: cytogenetic analysis;   Genetic: mutation analysis;   Genetic: polymorphism analysis;   Other: questionnaire administration
Study Type: Observational
Phase:
Funder Type: Other / NIH
Study Design:
Number Enrolled: 6900
Gender: Both
Age Groups: Child / Adult / Senior
NCT Number: NCT00082745
51 Recruiting Collecting and Storing Biological Samples From Young Patients With Hodgkin's Lymphoma
Condition: Lymphoma
Intervention: Other: biologic sample preservation procedure
Study Type: Observational
Phase:
Funder Type: Other / NIH
Study Design:
Number Enrolled: 1272
Gender: Both
Age Groups: Child / Adult / Senior
NCT Number: NCT00900250
52 Recruiting Collecting and Storing Blood and Brain Tumor Tissue Samples From Children With Brain Tumors
Condition: Brain and Central Nervous System Tumors
Intervention: Other: biologic sample preservation procedure
Study Type: Observational
Phase:
Funder Type: Other / NIH
Study Design:
Number Enrolled:
Gender: Both
Age Groups: Child / Adult
NCT Number: NCT00919750
53 Recruiting Collecting and Storing Tissue Samples From Patients With Rare or Cutaneous Non-Hodgkin Lymphoma
Conditions: Lymphoma;   Lymphoproliferative Disorder
Interventions: Other: biologic sample preservation procedure;   Other: informational intervention
Study Type: Observational
Phase:
Funder Type: Other / NIH
Study Design:
Number Enrolled:
Gender: Both
Age Groups: Child / Adult
NCT Number: NCT01000753
54 Recruiting Combination Chemotherapy in Treating Young Patients With Newly Diagnosed High-Risk Acute Lymphoblastic Leukemia
Conditions: Cognitive/Functional Effects;   Leukemia;   Neurotoxicity;   Pain;   Therapy-related Toxicity
Interventions: Drug: clofarabine;   Drug: cyclophosphamide;   Drug: cytarabine;   Drug: doxorubicin hydrochloride;   Drug: etoposide;   Drug: hydrocortisone sodium succinate;   Drug: leucovorin calcium;   Drug: mercaptopurine;   Drug: methotrexate;   Drug: pegaspargase;   Drug: prednisone;   Drug: thioguanine;   Drug: vincristine sulfate;   Radiation: selective external radiation therapy
Study Type: Interventional
Phase: Phase 3
Funder Type: Other / NIH
Study Design: Allocation: Randomized;   Masking: Open Label;   Primary Purpose: Treatment
Number Enrolled: 4450
Gender: Both
Age Groups: Child / Adult
NCT Number: NCT01406756
55 Recruiting Study of Kidney Tumors in Young Patients
Conditions: Kidney Cancer;   Nonneoplastic Condition
Interventions: Genetic: loss of heterozygosity analysis;   Genetic: polymerase chain reaction;   Genetic: polymorphism analysis;   Other: immunohistochemistry staining method;   Procedure: computed tomography;   Procedure: magnetic resonance imaging
Study Type: Observational
Phase:
Funder Type: Other / NIH
Study Design:
Number Enrolled:
Gender: Both
Age Groups: Child / Adult
NCT Number: NCT00898365
56 Recruiting Maintenance Chemotherapy or Observation Following Induction Chemotherapy and Radiation Therapy in Treating Younger Patients With Newly Diagnosed Ependymoma
Condition: Brain and Central Nervous System Tumors
Interventions: Drug: cisplatin;   Drug: cyclophosphamide;   Drug: etoposide;   Drug: vincristine sulfate;   Other: clinical observation;   Radiation: 3-dimensional conformal radiation therapy
Study Type: Interventional
Phase: Phase 3
Funder Type: Other / NIH
Study Design: Allocation: Randomized;   Masking: Open Label;   Primary Purpose: Treatment
Number Enrolled: 400
Gender: Both
Age Groups: Child / Adult
NCT Number: NCT01096368
57 Recruiting Collecting and Storing Tissue, Blood, and Bone Marrow Samples From Patients With Rhabdomyosarcoma or Other Soft Tissue Sarcoma
Conditions: Chordoma;   Desmoid Tumor;   Sarcoma
Interventions: Genetic: reverse transcriptase-polymerase chain reaction;   Other: biologic sample preservation procedure;   Other: laboratory biomarker analysis
Study Type: Observational
Phase:
Funder Type: Other / NIH
Study Design:
Number Enrolled:
Gender: Both
Age Groups: Child / Adult
NCT Number: NCT00919269
58 Recruiting Collecting and Storing Malignant, Borderline Malignant Neoplasms, and Related Samples From Young Patients With Cancer
Conditions: Leukemia;   Neoplasm of Uncertain Malignant Potential;   Unspecified Childhood Solid Tumor, Protocol Specific
Intervention: Other: cytology specimen collection procedure
Study Type: Observational
Phase:
Funder Type: Other / NIH
Study Design:
Number Enrolled:
Gender: Both
Age Groups: Child / Adult
NCT Number: NCT00898079
59 Recruiting Caspofungin Acetate or Fluconazole in Preventing Invasive Fungal Infections in Patients With Acute Myeloid Leukemia Who Are Undergoing Chemotherapy
Conditions: Fungal Infection;   Leukemia;   Neutropenia
Interventions: Drug: caspofungin acetate;   Drug: fluconazole
Study Type: Interventional
Phase: Phase 3
Funder Type: Other / NIH
Study Design: Allocation: Randomized;   Masking: Open Label;   Primary Purpose: Supportive Care
Number Enrolled: 550
Gender: Both
Age Groups: Child / Adult
NCT Number: NCT01307579
60 Recruiting Low-Dose or High-Dose Vincristine and Combination Chemotherapy in Treating Young Patients With Relapsed B-Cell Acute Lymphoblastic Leukemia
Condition: Leukemia
Interventions: Biological: filgrastim;   Drug: asparaginase;   Drug: cyclophosphamide;   Drug: cytarabine;   Drug: dexamethasone;   Drug: doxorubicin hydrochloride;   Drug: etoposide phosphate;   Drug: leucovorin calcium;   Drug: mercaptopurine;   Drug: methotrexate;   Drug: pegaspargase;   Drug: prednisone;   Drug: therapeutic hydrocortisone;   Drug: vincristine sulfate;   Radiation: radiation therapy
Study Type: Interventional
Phase: Phase 3
Funder Type: Other / NIH
Study Design: Allocation: Randomized;   Endpoint Classification: Efficacy Study;   Intervention Model: Parallel Assignment;   Masking: Open Label;   Primary Purpose: Treatment
Number Enrolled: 418
Gender: Both
Age Groups: Child / Adult
NCT Number: NCT00381680
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† Indicates status has not been verified in more than two years