23 studies found for:    "transthyretin amyloidosis"
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Rank Status Study
1 Unknown  Safety, Efficacy and Pharmacokinetics of Doxycycline Plus Tauroursodeoxycholic Acid in Transthyretin Amyloidosis
Condition: Transthyretin Amyloidosis
Intervention: Drug: Doxycycline + Tauroursodeoxycholic acid
2 Recruiting Tolerability and Efficacy of a Combination of Doxycycline and TUDCA in Patients With Transthyretin Amyloid Cardiomyopathy
Conditions: Amyloidosis; Heart (Manifestation);   Senile Cardiac Amyloidosis
Intervention: Drug: Tauroursodeoxycholic Acid and Doxycycline
3 Recruiting Efficacy and Safety of ISIS-TTR Rx in Familial Amyloid Polyneuropathy
Conditions: FAP;   Familial Amyloid Polyneuropathy;   TTR;   Transthyretin;   Amyloidosis
Interventions: Drug: ISIS-TTR Rx;   Drug: Placebo
4 Enrolling by invitation Open-Label Extension Assessing Long Term Safety and Efficacy of ISIS-TTR Rx in Familial Amyloid Polyneuropathy (FAP)
Condition: Familial Amyloid Polyneuropathy
Intervention: Drug: ISIS-TTR Rx
5 Active, not recruiting Prevalence of Transthyretin Amyloidosis in Hypertrophic Cardiomyopathy
Conditions: Cardiac Amyloidosis;   Amyloidosis in Transthyretin (TTR);   Hypertrophic Cardiomyopathy (HCM)
Intervention:
6 Completed
Has Results
An Extension of Study Fx-005 Evaluating Long-Term Safety And Clinical Outcomes Of Fx-1006A In Patients With Transthyretin Amyloid Polyneuropathy
Conditions: Familial Amyloid Polyneuropathy;   ATTR-PN
Intervention: Drug: Fx-1006A
7 Recruiting Imaging Cardiac Amyloidosis: A Pilot Study Using F-18 Florbetapir Positron Emission Tomography
Condition: Cardiac Amyloidosis
Intervention: Drug: F-18 florbetapir PET
8 Recruiting Study of SOM0226 in Familial Amyloid Polyneuropathy
Condition: Familial Amyloid Polyneuropathy (FAP)
Intervention: Drug: SOM0226
9 Completed The Effect Of Tafamidis For The Transthyretin Amyloid Polyneuropathy Patients With V30M Or Non-V30M Transthyretin
Condition: Transthyretin Familial Amyloid Polyneuropathy
Intervention: Drug: tafamidis
10 Enrolling by invitation Transthyretin-Associated Amyloidoses Outcome Survey (THAOS)
Conditions: Transthyretin Mutations;   Transthyretin Amyloidosis
Intervention: Other: None. Observational Study.
11 Recruiting Safety and Efficacy Study of Doxycycline/UrsoDeoxyCholicAcid on Disease Progression in ATTR Amyloidosis
Conditions: Transthyretin Amyloidosis;   Cardiomyopathy
Interventions: Drug: Doxycycline;   Drug: Ursodeoxycholic acid
12 Completed
Has Results
Safety and Efficacy Study of Fx-1006A in Patients With Familial Amyloidosis
Condition: Familial Amyloid Polyneuropathy
Interventions: Drug: Fx-1006A;   Drug: Placebo
13 Completed The Effect of Diflunisal on Familial Amyloidosis
Conditions: Familial Amyloid Polyneuropathy;   Familial Amyloidosis
Interventions: Drug: diflunisal;   Other: placebo
14 Enrolling by invitation Burden of Disease Study In Patients With Transthyretin Familial Amyloidosis Polyneuropathy (TTR-FAP) orTransthyretin Cardiomyopathy (TTR-CM) And Caregivers
Conditions: Transthyretin Familial Amyloidosis Polyneuropathy (TTR-FAP);   Transthyretin Cardiomyopathy (TTR-CM);   Familial Amyloid Cardiomyopathy;   Senile Systemic Amyloidosis (SSA)
Intervention: Other: No drug
15 Completed
Has Results
The Effects Of Fx-1006A On Transthyretin Stabilization And Clinical Outcome Measures In Patients With V122I Or Wild-Type TTR Amyloid Cardiomyopathy
Condition: Cardiomyopathy
Intervention: Drug: Fx-1006A
16 Recruiting Safety And Efficacy Evaluation Of Fx-1006A In Subjects With Transthyretin Amyloidosis
Condition: ATTR-PN
Intervention: Drug: Tafamidis
17 Recruiting The Effect of Diflunisal on Familial Transthyretin Amyloidosis
Condition: Amyloidosis
Intervention: Drug: Diflunisal
18 Completed
Has Results
The Effects of Fx-1006A on Transthyretin Stabilization and Clinical Outcome Measures in Patients With Non-V30M Transthyretin Amyloidosis
Condition: Transthyretin-associated Amyloidosis With Polyneuropathy
Intervention: Drug: Fx-1006A
19 Not yet recruiting Prevalence and Post-surgical Outcomes of CARdiac Wild-type TransthyrEtin amyloidoSIs in Elderly Patients With Aortic steNosis Referred for Valvular Replacement.
Conditions: Heart Disease;   Aging;   Amyloidosis;   Aortic Valve Stenosis
Intervention: Other: a basal LV septum biopsy
20 Recruiting Safety and Efficacy of Tafamidis in Patients With Transthyretin Cardiomyopathy
Condition: Transthyretin (TTR) Amyloid Cardiomyopathy
Interventions: Drug: Tafamidis;   Drug: Placebo

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Indicates status has not been verified in more than two years