167 studies found for:    "thrombotic thrombocytopenic purpura" OR "Purpura, Thrombocytopenic"
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Rank Status Study
1 Recruiting Genotype and Phenotype Correlation in Hereditary Thrombotic Thrombocytopenic Purpura (Upshaw-Schulman Syndrome)
Conditions: Thrombotic Thrombocytopenic Purpura;   Congenital Thrombotic Thrombocytopenic Purpura;   Familial Thrombotic Thrombocytopenic Purpura;   Thrombotic Thrombocytopenic Purpura, Congenital;   Upshaw-Schulman Syndrome
Intervention: Other: Observation
2 Completed ADAMTS13 in Thrombotic Thrombocytopenic Purpura
Condition: Thrombotic Thrombocytopenic Purpura
Intervention:
3 Withdrawn Use of Rituximab Treatment in Addition to Standard Care for Newly Presenting Thrombotic Thrombocytopenic Purpura
Condition: Thrombotic Thrombocytopenic Purpura
Intervention: Drug: Rituximab
4 Recruiting Safety Study of Danazol With Plasma Exchange and Steroids for the Treatment of Thrombotic Thrombocytopenic Purpura
Condition: Thrombotic Thrombocytopenic Purpura
Intervention: Drug: Danazol
5 Completed Rituximab in Adult Acquired Idiopathic Thrombotic Thrombocytopenic Purpura
Condition: Thrombotic Thrombocytopenic Purpura
Intervention: Drug: rituximab
6 Unknown  The Use of Rituximab in Acute Thrombotic Thrombocytopenic Purpura (TTP)
Condition: Thrombotic Thrombocytopenic Purpura (TTP)
Intervention: Drug: Rituximab
7 Recruiting Study of Cyclosporine or Corticosteroids as an Adjunct to Plasma Exchange in Thrombotic Thrombocytopenic Purpura (TTP)
Condition: Thrombotic Thrombocytopenic Purpura
Interventions: Drug: Cyclosporine;   Drug: Prednisone
8 Terminated Safety and Efficacy Study To Compare Uniplas With Cryosupernatant Plasma In Thrombotic Thrombocytopenic Purpura (TTP)
Condition: Thrombotic Thrombocytopenic Purpura (TTP)
Intervention: Drug: Uniplas
9 Completed Study to Assess Efficacy and Safety of Anti-von Willebrand Factor Nanobody in Patients With Acquired Thrombotic Thrombocytopenic Purpura (TTP)
Condition: Thrombotic Thrombocytopenic Purpura
Interventions: Biological: anti-vWF Nanobody;   Biological: Placebo
10 Recruiting Phase 1 Dose Escalation, Single Dose Study to Assess Safety and Pharmacokinetics of BAX930 in Hereditary Thrombotic Thrombocytopenic Purpura (TTP)
Condition: Hereditary Thrombotic Thrombocytopenic Purpura (TTP)
Intervention: Drug: Recombinant ADAMTS13
11 Recruiting Low Dose Rituximab in Thrombotic Thrombocytopenic Purpura
Condition: Thrombotic Thrombocytopenic Purpura
Intervention: Biological: rituximab
12 Unknown  Rituximab in Patients With Relapsed or Refractory TTP-HUS
Conditions: Thrombotic Thrombocytopenic Purpura;   Hemolytic Uremic Syndrome
Intervention: Drug: Rituximab
13 Not yet recruiting Octaplas Adult TTP Trial
Condition: Thrombotic Thrombocytopenic Purpura
Intervention: Biological: Octaplas
14 Terminated
Has Results
Evaluating the Effectiveness of Adding Rituximab to Standard Treatment for Thrombotic Thrombocytopenic Purpura (TTP)
Condition: Thrombotic Thrombocytopenic Purpura
Interventions: Drug: Rituximab;   Procedure: Plasma exchange;   Drug: Corticosteroids
15 Completed Study of AKR-501 Tablets Taken Orally Once Daily for 28 Days in Patients With Chronic Idiopathic Thrombocytopenic Purpura (ITP)
Conditions: Chronic Idiopathic Thrombocytopenic Purpura;   Purpura, Thrombocytopenic, Idiopathic
Interventions: Drug: Placebo;   Drug: AKR-501 Tablets
16 Completed
Has Results
Retrospective & Prospective Observational Study of Patients With Immune (Idiopathic) Thrombocytopenic Purpura (ITP)
Conditions: Idiopathic Thrombocytopenic Purpura;   Thrombocytopenia;   Thrombocytopenia in Subjects With Immune (Idiopathic) Thrombocytopenic Purpura (ITP);   Thrombocytopenic Purpura
Interventions: Other: Retrospective Chart Review;   Other: Patient-reported Outcome Questionnaires;   Other: Physician Survey
17 Completed
Has Results
Romiplostim (AMG 531) Versus Medical Standard of Care for Immune (Idiopathic) Thrombocytopenic Purpura
Conditions: Idiopathic Thrombocytopenic Purpura;   Thrombocytopenia;   Thrombocytopenia in Subjects With Immune (Idiopathic) Thrombocytopenic Purpura (ITP);   Thrombocytopenic Purpura
Interventions: Drug: Medical Standard of Care for ITP;   Biological: Romiplostim
18 Completed
Has Results
Clinical Evaluation of SB-497115-GR in Chronic Idiopathic Thrombocytopenic Purpura (ITP)
Conditions: Chronic Idiopathic Thrombocytopenic Purpura;   Purpura, Thrombocytopenic, Idiopathic
Interventions: Drug: SB-497115-GR 12.5mg;   Drug: SB-497115-GR 25mg;   Drug: SB-497115-GR 12.5mg matching placebo;   Drug: SB-497115-GR 50 mg
19 Completed An Epidemiological Study of Subjects With Immune Thrombocytopenic Purpura to Evaluate the Relationship Between Platelet Counts, Endogenous Thrombopoietin Levels, Endogenous Anti-Thrombopoietin Antibodies, and Selected Autoimmune Markers
Conditions: Purpura, Thrombocytopenic, Idiopathic;   Immune Thrombocytopenic Purpura
Intervention:
20 Terminated International Registry and Biorepository for TMA(Thrombotic Microangiopathy)
Conditions: Thrombotic Microangiopathy;   Hemolytic Uremic Syndrome;   Thrombotic Thrombocytopenic Purpura
Intervention:

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Indicates status has not been verified in more than two years