20 studies found for:    "potassium-aggravated myotonia" OR "Myotonic Disorders" OR "Myotonia Fluctuans"
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Rank Status Study
1 Recruiting Lamotrigine as Treatment of Myotonia
Conditions: Dystrophia Myotonica Type 1;   Myotonia Congenita;   Paramyotonia Congenita;   Hyperkalemic Periodic Paralysis;   Potassium-Aggravated Myotonia
Interventions: Drug: Lamotrigine;   Drug: Placebo
2 Completed Characteristics of Nondystrophic Myotonias
Conditions: Nondystrophic Myotonias;   Myotonia Congenita;   Myotonic Disorders
Intervention:
3 Completed Phase III Randomized, Double-Blind, Placebo-Controlled Study of Dichlorphenamide for Periodic Paralyses and Associated Sodium Channel Disorders
Conditions: Paralysis, Hyperkalemic Periodic;   Hypokalemic Periodic Paralysis;   Paramyotonia Congenita
Intervention: Drug: dichlorphenamide
4 Completed Postural Spirometry Changes in Ambulatory Myotonic Dystrophy Patients
Condition: Myotonic Dystrophy
Intervention: Other: Supine spirometry
5 Recruiting Myotonic Dystrophy and Facioscapulohumeral Muscular Dystrophy Registry
Conditions: Myotonic Dystrophy;   Muscular Dystrophy, Facioscapulohumeral;   Muscular Dystrophy
Intervention:
6 Completed Efficacy and Safety of DHEA for Myotonic Dystrophy
Condition: Myotonic Dystrophy
Intervention: Drug: dehydroepiandrosterone 100 and 400 mg
7 Active, not recruiting Efficacy and Tolerance of Early Launching of Nocturnal Non Invasive
Conditions: Myopathy;   Muscular Weakness;   Respiratory Insufficiency
Intervention: Device: Bilevel pressure ventilator
8 Completed
Has Results
Effects of SomatoKine (Iplex)Recombinant Human Insulin-like Growth Factor-1/Recombinant Human Insulin-like Growth Factor-binding Protein-3 (rhIGF-I/rhIGFBP-3) in Myotonic Dystrophy Type 1 (DM1)
Condition: Myotonic Dystrophy
Intervention: Drug: SomatoKine/IPLEX
9 Completed DM1 Heart Registry - DM1 Respiratory Registry
Condition: Myotonic Dystrophy
Intervention:
10 Recruiting Relations Between Myotonia and Fitness
Condition: Congenital Myotonia
Intervention: Other: Training
11 Unknown  Cardiovascular Consequences of NIV Withdrawal in Patients With Myotonic Dystrophy
Condition: Myotonia
Intervention: Other: withdrawal of non-invasive ventilation
12 Recruiting Efficacy and Tolerance of AVAPS Mode in Myotonic Dystrophy
Condition: Myopathy
Intervention: Device: Nocturnal ventilation
13 Completed Study of Muscle Wasting and Altered Metabolism in Patients With Myotonic Dystrophy
Condition: Myotonic Muscular Dystrophy
Intervention:
14 Recruiting Clinical Efficacy Trial of Mexiletine for Myotonic Dystrophy Type 1
Condition: Myotonic Dystrophy
Interventions: Drug: Mexiletine;   Drug: Placebo
15 Unknown  Safety and Efficacy Study of Recombinant Human Insulin-Like Growth Factor-I/Recombinant Human Insulin-Like Growth Factor Binding Protein-3 (rhIGF-I/rhIGFBP-3) In Myotonic Dystrophy Type 1
Condition: Myotonic Dystrophy Type 1
Interventions: Drug: rhIGF-I/rhIGFBP-3;   Drug: placebo
16 Recruiting Observational Prolonged Trial in Myotonic Dystrophy Type 1
Condition: Myotonic Dystrophy Type 1
Intervention: Behavioral: Behavioural change intervention
17 Unknown  RAMYD Study - Evaluation of Arrhythmic Risk in Myotonic Dystrophy
Conditions: Myotonic Dystrophy;   Sudden Cardiac Death
Interventions: Procedure: Electrophysiological study;   Device: pacemaker (PM) implant, internal cardiac defibrillator (ICD) implant, loop-recorder implant
18 Completed Methylphenidate in Myotonic Dystrophy Type 1
Condition: Dystrophia Myotonica 1
Interventions: Drug: Methylphenidate;   Drug: Placebo
19 Recruiting Variability of Molecular Biomarkers and Clinical Measures in People With Myotonic Dystrophy Type 1
Conditions: Muscle Myopathies;   Muscular Dystrophy;   Inherited Neuromuscular Conditions
Intervention:
20 Not yet recruiting Combined N-of-1 Trials Mexiletine vs Placebo in Patients With Non-Dystrophic Myotonia (NDM)
Condition: Non Dystrophic Myotonia
Interventions: Drug: Mexiletine;   Drug: Placebo

Indicates status has not been verified in more than two years