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12 studies found for:    "osteopetrosis"

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Rank Status Study
1 Recruiting Hematopoietic Stem Cell Transplantation for Malignant Infantile Osteopetrosis
Condition: Osteopetrosis
Interventions: Drug: Busulfan, Cyclophosphamide, Thymoglobulin, Fludarabine (Conditioning regimen);   Procedure: Stem Cell Transplantation;   Drug: Cyclosporin, Methotrexate (GVHD prophylaxis)
2 Terminated
Has Results 		Reduced Intensity AlloTransplant For Osteopetrosis
Condition: Osteopetrosis
Interventions: Procedure: Stem Cell or Umbilical Cord Blood Transplantation;   Drug: Campath, Busulfan, Clofarabine;   Procedure: Total Lymphoid Irradiation
3 Completed Post Marketing Surveillance Study of Actimmune in Patients With Severe, Malignant Osteopetrosis
Condition: Osteopetrosis
Intervention: Drug: Actimmune Registry
4 Terminated
Has Results 		Stem Cell Transplantation for Children Affected With Osteopetrosis
Condition: Osteopetrosis
Interventions: Procedure: Stem Cell Transplantation;   Device: Miltenyi Biotec CliniMACS;   Drug: Systemic chemotherapy and antibodies
5 Recruiting Allogeneic Transplantation For Severe Osteopetrosis
Condition: Severe Osteopetrosis
Interventions: Procedure: Stem Cell Transplantation;   Drug: Conditioning for transplantation-donor graft;   Radiation: Total Lymphoid Irradiation;   Drug: Conditioning for cord blood transplant
6 Completed Phase III Randomized Study of Interferon Gamma in Children With Severe, Congenital Osteopetrosis
Condition: Osteopetrosis
Interventions: Drug: calcitriol;   Drug: interferon gamma
7 Recruiting Unrelated Hematopoietic Stem Cell Transplantation(HSCT) for Genetic Diseases of Blood Cells
Conditions: Sickle Cell Disease;   Thalassemia;   Anemia;   Granuloma;   Wiskott-Aldrich Syndrome;   Chediak Higashi Syndrome;   Osteopetrosis;   Neutropenia;   Thrombocytopenia;   Hurler Disease;   Niemann-Pick Disease;   Fucosidosis
Intervention: Procedure: Hematopoietic stem cell transplantation
8 Available Expanded Access Protocol (EAP) Using the CliniMACS® Device for Pediatric Haplocompatible Donor Stem Cell Transplant
Conditions: Acute Lymphoblastic Leukemia;   Acute Myeloid Leukemia;   Chronic Myeloid Leukemia;   Myelodysplastic Syndrome;   Lymphomas;   Bone Marrow Failure;   Hemoglobinopathy;   Immune Deficiency;   Osteopetrosis;   Cytopenias;   White Blood Cell Abnormalities;   Red Blood Cell Abnormalities
Intervention: Biological: CD34+ enriched, T Cell Depleted donor stem cell product
9 Active, not recruiting rhPTH Therapy for Low Turnover Bone Fragility
Condition: Osteopetrosis
Intervention: Drug: Forteo (teriparatide)
10 Completed Clinical Assessment of Patients With High Bone Mass Due to Mutation in Lrp5
Condition: Osteopetrosis
Intervention:
11 Recruiting T-cell Depleted Alternative Donor Transplantation
Conditions: Acute Lymphoblastic Leukemia;   Acute Myeloid Leukemia;   Chronic Myeloid Leukemia;   Myelodysplastic Syndrome;   Lymphomas;   Bone Marrow Failure;   Hemoglobinopathy;   Immune Deficiency;   Osteopetrosis
Intervention: Device: CliniMACS® (T cell depletion)
12 Recruiting Risk-Adapted Allogeneic Stem Cell Transplantation For Mixed Donor Chimerism In Patients With Non-Malignant Diseases
Conditions: Bone Marrow Failure;   Osteopetrosis;   Fanconi Anemia;   Severe Combined Immunodeficiency
Interventions: Drug: Fludarabine;   Drug: Cyclophosphamide;   Drug: Cyclophosphamide 40;   Drug: Cyclophosphamide 30
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† Indicates status has not been verified in more than two years