90 studies found for:    "neurofibromatosis type 1"
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Rank Status Study
21 Active, not recruiting A Phase II Study of the mTOR Inhibitor Sirolimus in Neurofibromatosis Type 1 Related Plexiform Neurofibromas
Condition: Neurofibromatosis Type 1
Intervention: Drug: Sirolimus, Rapamycin
22 Recruiting Natural History Study of Patients With Neurofibromatosis Type I
Conditions: Neurofibromatosis Type 1;   Malignant Peripheral Nerve Sheath Tumor;   Plexiform Neurofibroma;   Optic Glioma;   Neurofibroma
Intervention:
23 Active, not recruiting Effects of Physical Training on Bone and Muscle Quality, Muscle Strength, and Motor Coordination in Children With NF1
Condition: Neurofibromatosis Type 1
Intervention: Other: Plyometric training program
24 Unknown  Analysis of Peripheral Nerve Sheath Tumors (PNSTs) in Neurofibromatosis Type 1 (NF1) Patients
Condition: Neurofibromatosis Type 1
Intervention:
25 Active, not recruiting Sirolimus to Treat Plexiform Neurofibromas in Patients With Neurofibromatosis Type I
Conditions: Neurofibromatosis Type 1;   Plexiform Neurofibromas;   Paraspinal Plexiform Neurofibromas
Intervention: Drug: Sirolimus
26 Unknown  Microarray CGH Analysis of Circulating Tumoral Plasma DNA in NF1 Patients With MPNSTs
Condition: Neurofibromatosis Type 1
Intervention:
27 Recruiting MicroRNAs in Patients With Neurofibromatosis Type 1
Conditions: Glioma;   Neurofibromatosis Type 1
Intervention:
28 Active, not recruiting Study of Disease Severity in Adults With Neurofibromatosis Type 1 (NF1)
Condition: Neurofibromatosis Type I
Intervention:
29 Recruiting Trial to Evaluate the Safety of Lovastatin in Individuals With Neurofibromatosis Type I (NF1)
Condition: Neurofibromatosis 1
Interventions: Drug: Lovastatin;   Drug: placebo pill
30 Not yet recruiting Ophthalmological Screening and Follow-up of Optic Pathway Gliomas in Children With Neurofibromatosis Type 1.
Condition: Neurofibromatosis Type 1
Intervention:
31 Completed
Has Results
AZD2171 in Treating Patients With Neurofibromatosis Type 1 and Plexiform Neurofibroma and/or Neurofibroma Near the Spine
Conditions: Neurofibromatosis Type 1;   Plexiform Neurofibroma;   Spinal Cord Neurofibroma
Intervention: Drug: cediranib maleate
32 Active, not recruiting Ranibizumab for Neurofibromas Associated With Neurofibromatosis 1
Conditions: Neurofibromatosis Type 1;   Cutaneous Neurofibromas
Intervention: Drug: Ranibizumab
33 Active, not recruiting MEK Inhibitor PD-0325901 Trial in Adolescents and Adults With NF1
Condition: Neurofibromatosis Type 1 and Growing or Symptomatic, Inoperable PN
Intervention: Drug: PD-0325901
34 Completed Sorafenib to Treat Children and Young Adults With Neurofibromatosis Type 1 and Inoperable Plexiform Neurofibromas
Conditions: Neurofibromatosis Type I;   Plexiform Neurofibroma
Interventions: Drug: Nexavar (BAY 43-9006) (Sorafenib);   Drug: Toxicity, Pharmacokinetics;   Drug: Pharmacodynamics;   Drug: Radiographic Evaluation;   Drug: QOL assessment, Neuropsychological;   Drug: Bony Toxicity
35 Recruiting Pegintron to Treat Plexiform Neurofibromas in Children and Young Adults
Conditions: Neurofibromatosis Type 1;   Plexiform Neurofibroma
Intervention: Drug: PEG-interferon alfa-2b
36 Active, not recruiting Topical Imiquimod 5% Cream for Treatment of Cutaneous Neurofibromas in Adults With Neurofibromatosis 1
Conditions: Neurofibromatosis Type 1;   Cutaneous Neurofibromas
Intervention: Drug: Imiquimod 5% Cream
37 Completed Topical Rapamycin Therapy to Alleviate Cutaneous Manifestations of Tuberous Sclerosis Complex (TSC) and Neurofibromatosis I (NF1)
Conditions: Tuberous Sclerosis;   Neurofibromatoses;   Angiofibroma;   Neurofibroma
Interventions: Drug: Skincerity;   Drug: Skincerity plus sirolimus/rapamycin;   Drug: Skinercity plus sirolimus/rapamycin
38 Active, not recruiting Pilot Study of Gleevec/Imatinib Mesylate (STI-571, NSC 716051) in Neurofibromatosis (NF1) Patient With Plexiform Neurofibromas
Conditions: Neurofibromatosis;   Neurofibromas
Intervention: Drug: Gleevec
39 Completed Phase II Study of Gleevec/Imatinib Mesylate (STI-571, NCS 716051) in Neurofibromatosis (NF1) Patients With Plexiform Neurofibromas
Condition: Neurofibromatosis
Intervention: Drug: Gleevec
40 Completed
Has Results
R115777 to Treat Children With Neurofibromatosis Type 1 and Progressive Plexiform Neurofibromas
Conditions: Neurofibroma, Plexiform;   Neurofibromatosis Type I
Interventions: Drug: tipifarnib;   Other: placebo

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Indicates status has not been verified in more than two years