42 studies found for:    "narcolepsy"
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Rank Status Study
21 Not yet recruiting A Multicenter Study of the Efficacy and Safety of Xyrem With an Open- Label Pharmacokinetic Evaluation and Safety Extension in Pediatric Subjects With Narcolepsy With Cataplexy
Condition: Narcolepsy With Cataplexy
Intervention: Drug: Xyrem
22 Completed Efficacy and Safety Study of BF2.649 and BF2.649 Add on Modafinil on Cataplexy in Patients With Narcolespy
Conditions: Narcolepsy;   Cataplexy;   Excessive Daytime Sleepiness
Interventions: Drug: BF2.649;   Drug: BF2.649 add on Modafinil
23 Completed Assess the Safety and Effectiveness of PROVIGIL Treatment in Children and Adolescents With Excessive Sleepiness
Condition: Narcolepsy
Intervention: Drug: Modafinil
24 Completed
Has Results
Extension Study of the Safety and Efficacy of Armodafinil in the Treatment of Patients With Excessive Sleepiness
Conditions: Excessive Daytime Sleepiness;   Narcolepsy;   Obstructive Sleep Apnea/Hypopnea Syndrome;   Chronic Shift Work Sleep Disorder
Intervention: Drug: Armodafinil 100 to 250 mg/day
25 Completed Exploratory Clinical Study to Evaluate Sodium Oxybate (Xyrem) on Potential Endocrine Changes
Condition: Narcolepsy With Cataplexy
Intervention: Drug: Sodium Oxybate (Xyrem)
26 Completed
Has Results
Clarithromycin for the Treatment of Hypersomnia
Conditions: Hypersomnia;   Idiopathic Hypersomnia;   Narcolepsy
Interventions: Drug: Clarithromycin followed by placebo;   Drug: Placebo then Clarithromycin
27 Completed Sleep Disorders of Patients With Diseases of the Nervous System
Conditions: Hypersomnia;   Narcolepsy;   Nervous System Disease;   Sleep Disorder
Intervention:
28 Unknown  Effect of Intranasal Administration of Orexine A on IL-6-System, Sleep-Wake-Regulation and Neurocognition
Condition: Narcolepsy
Intervention: Drug: Orexine A
29 Enrolling by invitation Observational Study to Evaluate Risks of Side Effects, Drug Abuse and Dependence in Patients Who Received Xyrem ® on Prescription
Condition: Narcolepsy
Intervention:
30 Recruiting Pitolisant to Assess Weekly Frequency of Cataplexy Attacks and EDS in Narcoleptic Patients (HARMONY CTP)
Conditions: Narcolepsy With Cataplexy;   Excessive Daytime Sleepiness
Interventions: Drug: Pitolisant;   Drug: Placebo
31 Completed
Has Results
Flumazenil for the Treatment of Primary Hypersomnia
Conditions: Hypersomnia;   Primary Hypersomnia;   Idiopathic Hypersomnia;   Narcolepsy Without Cataplexy
Intervention: Drug: Flumazenil
32 Completed Method of Assessment of Driving Ability in Patients Suffering From Wakefulness Pathologies
Conditions: Narcolepsy;   Hypersomnia
Interventions: Drug: Modafinil;   Drug: Placebo
33 Recruiting The Nuvigil and Provigil Pregnancy Registry
Conditions: Narcolepsy;   Obstructive Sleep Apnea;   Shift Work Sleep Disorder
Intervention: Drug: Modafinil/armodafinil
34 Active, not recruiting Patient Narcoleptic Treated With BF2.649 (Pitolisant) in add-on to Sodium Oxybate (HARMONY IV)
Condition: Narcolepsy
Intervention: Drug: BF2.649
35 Recruiting Neurophysiologic Correlates of Hypersomnia
Conditions: Major Depressive Disorder;   Primary Hypersomnia;   Bipolar Disorder;   Narcolepsy;   Primary Insomnia
Intervention: Other: Acoustical slow wave induction
36 Completed A Study of the Safety and Effectiveness of ADX-N05 in the Treatment of Excessive Daytime Sleepiness
Condition: Narcolepsy
Interventions: Drug: ADX-N05;   Drug: Placebo
37 Recruiting Sustainable Methods, Algorithms, and Research Tools for Delivering Optimal Care Study
Conditions: Obstructive Sleep Apnea of Adult;   Insomnia;   Circadian Rhythm Sleep Disorder, Unspecified Type;   Restless Legs Syndrome;   Narcolepsy and Hypersomnia
Interventions: Other: CONV care for the diagnosis and treatment of sleep disorders;   Other: PCCM for the diagnosis and treatment of sleep disorders
38 Completed Single-dose Safety Study of APD916 in Healthy Volunteers
Condition: Narcolepsy With or Without Cataplexy
Intervention: Drug: APD916
39 Active, not recruiting A Phase 1, Single Dose Study of JZP-386 to Evaluate Safety, Pharmacokinetics and Pharmacodynamics
Condition: Narcolepsy, Excessive Daytime Sleepiness
Interventions: Drug: Placebo;   Drug: Sodium Oxybate;   Drug: JZP-386
40 Recruiting Amylase and Hypersomnia
Condition: Hypersomnia in Children
Intervention: Procedure: saliva collection

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Indicates status has not been verified in more than two years